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A0A8T3VY16 · A0A8T3VY16_METOL

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site9-10ATP (UniProtKB | ChEBI)
Binding site43UMP (UniProtKB | ChEBI)
Binding site44ATP (UniProtKB | ChEBI)
Binding site48ATP (UniProtKB | ChEBI)
Binding site65UMP (UniProtKB | ChEBI)
Binding site113-119UMP (UniProtKB | ChEBI)
Binding site139ATP (UniProtKB | ChEBI)
Binding site145ATP (UniProtKB | ChEBI)
Binding site148ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      E7Z75_07130

Organism names

  • Taxonomic identifier
  • Strain
    • SIG14
  • Taxonomic lineage
    Archaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > Methanobrevibacter

Accessions

  • Primary accession
    A0A8T3VY16

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-202Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    225
  • Mass (Da)
    24,416
  • Last updated
    2022-10-12 v1
  • MD5 Checksum
    C443C6E133713BC029F6C3354EFE8557
MRIVAAIGGSILLQDYNAERFKEYARLLKEQSEEHEIFVVVGGGKPAREYIGVVRDLGAGEAKCDDIGIEVTRVNAKLLLLALGDAAYQRVPHNFQEALEFSASGKIIVMGGTEPAHSTDAVSAILAEYVQADLLVNLTAVDGLYTKDPKKYDDAELIEEITASDMMGIISGNDVKAGTYEFIDTTAIQMIKRSNLETVIANGNEPQNLIRAIKGEKIGTRVISE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SUTG01000035
EMBL· GenBank· DDBJ
MBE6512895.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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