A0A8T2D4S4 · A0A8T2D4S4_9BRAS
- Proteinglutamate synthase (NADH)
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2208 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 2 L-glutamate + NAD+ = 2-oxoglutarate + H+ + L-glutamine + NADH
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 [3Fe-4S] cluster.
Pathway
Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3 iron, 4 sulfur cluster binding | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | FMN binding | |
Molecular Function | glutamate synthase (NADH) activity | |
Molecular Function | iron ion binding | |
Biological Process | glutamate biosynthetic process | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameglutamate synthase (NADH)
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionA0A8T2D4S4
Proteomes
Structure
Family & Domains
Features
Showing features for domain, region, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 117-521 | Glutamine amidotransferase type-2 | ||||
Sequence: CGVGFVAELSGETTRKTVTDSLEMLIRMTHRGACGCESNTGDGAGILVGLPHDFYAEAATELGFVLPSAGNYAVGMFFLPTVESRREESKNVFTKVAESLGHSVLGWRLVPTDNSGLGNSALQTEPIIAQVFLTPTTKSKADFEQQMYILRRVSMVAIRAALNLQHGAMKDFYICSLSSRTIVYKGQLKPDQLKDYYFADLGSERFTSYMALVHSRFSTNTFPSWDRAQPMRVLGHNGEINTLRGNVNWMRAREGLLKCNELGLSKKELKKLLPIVDVSSSDSGAFDGVLELLVRAGRSLPEAVMMMIPEAWQNDKNIDPSRKEFYEYLSALMEPWDGPALISFTDGRYLGATLDRNGLRPGRFYITHSGRVIMASEVGVVDVPPEDVMRKGRLNPGMMLLVDFE | ||||||
Region | 1040-1066 | Disordered | ||||
Sequence: GKSNTGEGGELPSRMEPLTDGSRNPKR | ||||||
Coiled coil | 1639-1666 | |||||
Sequence: EEVTKQAIERASEEADETEEKELEEKDA |
Sequence similarities
Belongs to the glutamate synthase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,208
- Mass (Da)241,959
- Last updated2022-10-12 v1
- Checksum957BB2430B9C3179