A0A8T0PGL9 · A0A8T0PGL9_PANVG

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site111substrate 1; for methylthioribulose-1-phosphate dehydratase activity
Binding site129Zn2+ (UniProtKB | ChEBI)
Binding site131Zn2+ (UniProtKB | ChEBI)
Active site154Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity
Binding site204Zn2+ (UniProtKB | ChEBI)
Binding site278Mg2+ (UniProtKB | ChEBI)
Binding site280Mg2+ (UniProtKB | ChEBI)
Binding site413-414substrate 2; for enolase-phosphatase activity
Binding site447substrate 2; for enolase-phosphatase activity
Binding site473Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
Molecular Function2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
Molecular Functionacireductone synthase activity
Molecular Functionmagnesium ion binding
Molecular Functionmethylthioribulose 1-phosphate dehydratase activity
Molecular Functionzinc ion binding
Biological ProcessL-methionine salvage from methylthioadenosine
Biological ProcessL-methionine salvage from S-adenosylmethionine

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1

Including 2 domains:

  • Recommended name
    Methylthioribulose-1-phosphate dehydratase
  • EC number
  • Short names
    MTRu-1-P dehydratase
  • Recommended name
    Enolase-phosphatase E1
  • EC number
  • Alternative names
    • 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Gene names

    • ORF names
      PVAP13_8NG239500

Organism names

  • Taxonomic identifier
  • Strain
    • AP13
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Panicodae > Paniceae > Panicinae > Panicum > Panicum sect. Hiantes

Accessions

  • Primary accession
    A0A8T0PGL9

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-239Methylthioribulose-1-phosphate dehydratase
Domain28-231Class II aldolase/adducin N-terminal
Region275-517Enolase-phosphatase E1

Sequence similarities

In the C-terminal section; belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
In the N-terminal section; belongs to the aldolase class II family. MtnB subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    517
  • Mass (Da)
    57,336
  • Last updated
    2022-10-12 v1
  • Checksum
    D4DCB03F015F9107
MASCCETEAAAVTTEAYLAGAAVREARELVAELCRHFYAPGWVTGTGGSITVKVNDPAVPLADRLIVMSPSGVQKERMVAADMYVFSADGKVLSEPAAKPWPNKPPKCTDCAPLFMKAYQMRGAGAVIHSHGIETCIASMLDPGAKEFRMTHMEMLKAIKGHGYRDELVIPIIENTPYEYELTDSLSEAIAAYPKATAVLVRNHGIFVWGDSWISAKTQAESYHYLLDAAIKLYQLGIDWTTPEHGPVNRAKRSRSILNPGIPNECHAAEPLKCVVLDIEGTTTPISFVTDVMFPYARDNVRKHLTSTFYSEETKEDIKLLRVQIEDDLRNGIPGAVPVPPDEAGKEEVINSLVANVESMIEADWKVTSLKQLQGHIWRTGFEREEIHGVIFEDVPEALKNWNSRNIKVYIYSSGSREAQRLLFGNTEHGDLRPFLCGYFDTTIGNKKETRSYFEIAQTLRVDSPSQILFITDVFQEAIAAKNAGFEVVISIRPGNAPVPENHGFRTIKSLSEVCER

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8T0PEB1A0A8T0PEB1_PANVGPVAP13_8NG239500530
A0A8T0P9N4A0A8T0P9N4_PANVGPVAP13_8NG239500417
A0A8T0P5Z3A0A8T0P5Z3_PANVGPVAP13_8NG239500523
A0A8T0P729A0A8T0P729_PANVGPVAP13_8NG239500487

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM029052
EMBL· GenBank· DDBJ
KAG2557564.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp