A0A8T0P6L2 · A0A8T0P6L2_PANVG
- ProteinPHD finger protein ALFIN-LIKE
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids186 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | histone binding | |
Molecular Function | metal ion binding | |
Molecular Function | transcription cis-regulatory region binding | |
Molecular Function | transcription coregulator activity | |
Biological Process | chromatin organization | |
Biological Process | regulation of DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended namePHD finger protein ALFIN-LIKE
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Panicodae > Paniceae > Panicinae > Panicum > Panicum sect. Hiantes
Accessions
- Primary accessionA0A8T0P6L2
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-22 | ||||
Chain | PRO_5035852328 | 23-186 | PHD finger protein ALFIN-LIKE | ||
Interaction
Subunit
Interacts with H3K4me3 and to a lesser extent with H3K4me2.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 70-129 | Disordered | |||
Compositional bias | 84-98 | Polar residues | |||
Compositional bias | 113-127 | Acidic residues | |||
Domain | 128-180 | PHD-type | |||
Domain
The PHD-type zinc finger mediates the binding to H3K4me3.
Sequence similarities
Belongs to the Alfin family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length186
- Mass (Da)20,734
- Last updated2022-10-12 v1
- MD5 Checksum1E09CAB3471C8EAA3BF083B93D39D8FA
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8T0P761 | A0A8T0P761_PANVG | PVAP13_8NG196400 | 255 | ||
A0A8T0PDT7 | A0A8T0PDT7_PANVG | PVAP13_8NG196400 | 254 | ||
A0A8T0P3J4 | A0A8T0P3J4_PANVG | PVAP13_8NG196400 | 225 | ||
A0A8T0PBJ9 | A0A8T0PBJ9_PANVG | PVAP13_8NG196400 | 243 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 84-98 | Polar residues | |||
Compositional bias | 113-127 | Acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM029052 EMBL· GenBank· DDBJ | KAG2556638.1 EMBL· GenBank· DDBJ | Genomic DNA |