A0A8S4QD60 · A0A8S4QD60_CAEEL
- ProteinMevalonate kinase
- Genemvk-1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids707 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Pathway
Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | mevalonate kinase activity | |
Biological Process | cholesterol biosynthetic process | |
Biological Process | isopentenyl diphosphate biosynthetic process, mevalonate pathway | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionA0A8S4QD60
Proteomes
Organism-specific databases
Subcellular Location
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 88-140 | Disordered | ||||
Sequence: VESTELSVTSKESTEQLPSKDSLDSPSGSTSRAGSSVSATASPMHRNTTSQHG | ||||||
Region | 313-341 | Disordered | ||||
Sequence: LTPLPSPGAQSTAPPVFPTSTPTPTSTPT | ||||||
Domain | 365-447 | GHMP kinase N-terminal | ||||
Sequence: TVRFKLPSCVGLGSSGAYCVCIATSLLQTAGLIPPPSIVADEQGNLTWEEDHLDIIRKWATAAESLIHGRASGLDAAVCTFGG | ||||||
Region | 522-585 | Disordered | ||||
Sequence: ENGGGDTGSTVQENGLGPFGGNMVEQDHHSLQPTRTASVRSSSLSSYVGGGKRNSSASVISATS | ||||||
Compositional bias | 548-585 | Polar residues | ||||
Sequence: DHHSLQPTRTASVRSSSLSSYVGGGKRNSSASVISATS | ||||||
Domain | 595-655 | GHMP kinase C-terminal | ||||
Sequence: SKLNDLCRINNQLLIALGVGHPKVDLICTTLARYGIHPKMTGAGGGGSVFAFLKPNTPQTL |
Family and domain databases
Sequence
- Sequence statusComplete
- Length707
- Mass (Da)75,381
- Last updated2022-10-12 v1
- ChecksumAFAAF7CFFE0D0787
Computationally mapped potential isoform sequences
There are 17 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8S4QB65 | A0A8S4QB65_CAEEL | mvk-1 | 737 | ||
A0A8S4Q9F9 | A0A8S4Q9F9_CAEEL | mvk-1 | 623 | ||
Q9N4Z7 | Q9N4Z7_CAEEL | mvk-1 | 607 | ||
A0A8S4QFB7 | A0A8S4QFB7_CAEEL | mvk-1 | 635 | ||
A0A8S4QGK9 | A0A8S4QGK9_CAEEL | mvk-1 | 716 | ||
A0A8S4QAY9 | A0A8S4QAY9_CAEEL | mvk-1 | 728 | ||
A0A8S4QB79 | A0A8S4QB79_CAEEL | mvk-1 | 505 | ||
Q65XX8 | Q65XX8_CAEEL | mvk-1 | 484 | ||
Q65XX9 | Q65XX9_CAEEL | mvk-1 | 614 | ||
Q65XY0 | Q65XY0_CAEEL | mvk-1 | 514 | ||
A0A8S4QD98 | A0A8S4QD98_CAEEL | mvk-1 | 577 | ||
A0A8S4QCH2 | A0A8S4QCH2_CAEEL | mvk-1 | 535 | ||
A0A8S4QCI1 | A0A8S4QCI1_CAEEL | mvk-1 | 74 | ||
A0A8S4QD84 | A0A8S4QD84_CAEEL | mvk-1 | 628 | ||
A0A8S4QBV1 | A0A8S4QBV1_CAEEL | mvk-1 | 644 | ||
A0A8S4QBV5 | A0A8S4QBV5_CAEEL | mvk-1 | 598 | ||
A0A8S4QBX2 | A0A8S4QBX2_CAEEL | mvk-1 | 164 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 548-585 | Polar residues | ||||
Sequence: DHHSLQPTRTASVRSSSLSSYVGGGKRNSSASVISATS |
Keywords
- Technical term