A0A8S4QD60 · A0A8S4QD60_CAEEL

  • Protein
    Mevalonate kinase
  • Gene
    mvk-1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmevalonate kinase activity
Biological Processcholesterol biosynthetic process
Biological Processisopentenyl diphosphate biosynthetic process, mevalonate pathway
Biological Processphosphorylation

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Mevalonate kinase

Gene names

    • Name
      mvk-1
    • ORF names
      CELE_Y42G9A.4
      , Y42G9A.4

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    A0A8S4QD60

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Structure

3D structure databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region88-140Disordered
Region313-341Disordered
Domain365-447GHMP kinase N-terminal
Region522-585Disordered
Compositional bias548-585Polar residues
Domain595-655GHMP kinase C-terminal

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    707
  • Mass (Da)
    75,381
  • Last updated
    2022-10-12 v1
  • Checksum
    AFAAF7CFFE0D0787
MPVAAPEEHEKVVTVCGELVRSLDANGKEMVIRREVSVTETRESRDTSLKVEIPSEQEIELPVIVHDKPKLIKQEVSVVEPLELQESVESTELSVTSKESTEQLPSKDSLDSPSGSTSRAGSSVSATASPMHRNTTSQHGGLFVSAPGKIILFGEHAVVYGRTAIAGSIDLRTYVSLYTSADGRIYLSLPDLGVEKTWMLKDLLKAADRLAAEYPIEEDQPPSLEILVPIARKLSGSCEDQCGVQHLAILAFWYLLLGVAHRKSGLSRLARGLPAPPLPEGLHRTNLSVIGATSAQPEKSEAEIALSLPVPPLTPLPSPGAQSTAPPVFPTSTPTPTSTPTPLLPGNLRADSPAVQQDLLAVKATVRFKLPSCVGLGSSGAYCVCIATSLLQTAGLIPPPSIVADEQGNLTWEEDHLDIIRKWATAAESLIHGRASGLDAAVCTFGGVASFKPGHRIEHLKNLPDLRVILVNSKVERNTARMVQTVKERLKKFPEVVDAMFGSIDAISLDAAKILHRPLLEENGGGDTGSTVQENGLGPFGGNMVEQDHHSLQPTRTASVRSSSLSSYVGGGKRNSSASVISATSEKGENVDTFSKLNDLCRINNQLLIALGVGHPKVDLICTTLARYGIHPKMTGAGGGGSVFAFLKPNTPQTLLDMIDGELRSHGFEVWQPPLGGPGVVEHQTRPELFQTPVSSTQCSTPASKHK

Computationally mapped potential isoform sequences

There are 17 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8S4QB65A0A8S4QB65_CAEELmvk-1737
A0A8S4Q9F9A0A8S4Q9F9_CAEELmvk-1623
Q9N4Z7Q9N4Z7_CAEELmvk-1607
A0A8S4QFB7A0A8S4QFB7_CAEELmvk-1635
A0A8S4QGK9A0A8S4QGK9_CAEELmvk-1716
A0A8S4QAY9A0A8S4QAY9_CAEELmvk-1728
A0A8S4QB79A0A8S4QB79_CAEELmvk-1505
Q65XX8Q65XX8_CAEELmvk-1484
Q65XX9Q65XX9_CAEELmvk-1614
Q65XY0Q65XY0_CAEELmvk-1514
A0A8S4QD98A0A8S4QD98_CAEELmvk-1577
A0A8S4QCH2A0A8S4QCH2_CAEELmvk-1535
A0A8S4QCI1A0A8S4QCI1_CAEELmvk-174
A0A8S4QD84A0A8S4QD84_CAEELmvk-1628
A0A8S4QBV1A0A8S4QBV1_CAEELmvk-1644
A0A8S4QBV5A0A8S4QBV5_CAEELmvk-1598
A0A8S4QBX2A0A8S4QBX2_CAEELmvk-1164

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias548-585Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284603
EMBL· GenBank· DDBJ
CAH2176181.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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