A0A8R2JQA5 · A0A8R2JQA5_ACYPI
- ProteinA disintegrin and metalloproteinase with thrombospondin motifs 9
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1879 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 282 | Zn2+ (UniProtKB | ChEBI); catalytic; in inhibited form | |||
Binding site | 351 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 351 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 438 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 438 | Ca2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 445 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 498 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 499 | ||||
Binding site | 502 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 508 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 559 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 562 | Ca2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 562 | Ca2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | membrane | |
Molecular Function | metalloendopeptidase activity | |
Molecular Function | zinc ion binding | |
Biological Process | extracellular matrix organization | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameA disintegrin and metalloproteinase with thrombospondin motifs 9
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Sternorrhyncha > Aphidomorpha > Aphidoidea > Aphididae > Macrosiphini > Acyrthosiphon
Accessions
- Primary accessionA0A8R2JQA5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 12-34 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 427↔482 | ||||
Disulfide bond | 456↔464 | ||||
Disulfide bond | 477↔559 | ||||
Disulfide bond | 514↔543 | ||||
Disulfide bond | 591↔613 | ||||
Disulfide bond | 602↔623 | ||||
Disulfide bond | 608↔643 | ||||
Disulfide bond | 636↔648 | ||||
Disulfide bond | 672↔709 | ||||
Disulfide bond | 676↔714 | ||||
Disulfide bond | 687↔699 | ||||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 61-98 | Disordered | |||
Region | 263-299 | Disordered | |||
Compositional bias | 266-291 | Polar residues | |||
Domain | 348-564 | Peptidase M12B | |||
Region | 1543-1585 | Disordered | |||
Compositional bias | 1553-1572 | Basic and acidic residues | |||
Domain | 1672-1879 | GON | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,879
- Mass (Da)207,866
- Last updated2022-10-12 v1
- ChecksumC3455105DBCD1654
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 266-291 | Polar residues | |||
Compositional bias | 1553-1572 | Basic and acidic residues | |||
Keywords
- Technical term