A0A8R2JQA5 · A0A8R2JQA5_ACYPI

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

118792004006008001,0001,2001,4001,6001,800
Type
IDPosition(s)Description
Binding site282Zn2+ (UniProtKB | ChEBI); catalytic; in inhibited form
Binding site351Ca2+ 2 (UniProtKB | ChEBI)
Binding site351Ca2+ 1 (UniProtKB | ChEBI)
Binding site438Ca2+ 1 (UniProtKB | ChEBI)
Binding site438Ca2+ 2 (UniProtKB | ChEBI)
Binding site445Ca2+ 1 (UniProtKB | ChEBI)
Binding site498Zn2+ (UniProtKB | ChEBI); catalytic
Active site499
Binding site502Zn2+ (UniProtKB | ChEBI); catalytic
Binding site508Zn2+ (UniProtKB | ChEBI); catalytic
Binding site559Ca2+ 1 (UniProtKB | ChEBI)
Binding site562Ca2+ 1 (UniProtKB | ChEBI)
Binding site562Ca2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextracellular region
Cellular Componentmembrane
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processextracellular matrix organization
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    A disintegrin and metalloproteinase with thrombospondin motifs 9

Organism names

  • Taxonomic identifier
  • Strain
    • LSR1
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Sternorrhyncha > Aphidomorpha > Aphidoidea > Aphididae > Macrosiphini > Acyrthosiphon

Accessions

  • Primary accession
    A0A8R2JQA5

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-34Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond427↔482
Disulfide bond456↔464
Disulfide bond477↔559
Disulfide bond514↔543
Disulfide bond591↔613
Disulfide bond602↔623
Disulfide bond608↔643
Disulfide bond636↔648
Disulfide bond672↔709
Disulfide bond676↔714
Disulfide bond687↔699

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region61-98Disordered
Region263-299Disordered
Compositional bias266-291Polar residues
Domain348-564Peptidase M12B
Region1543-1585Disordered
Compositional bias1553-1572Basic and acidic residues
Domain1672-1879GON

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,879
  • Mass (Da)
    207,866
  • Last updated
    2022-10-12 v1
  • Checksum
    C3455105DBCD1654
MSSKTSVRAPTAKWPLIVALSVMSASILVATIAWTATGHLQATSTERFDGTVTELVKSANDTVVKESEDDDSQSDETQTMSMVPESLRKKSSMVDTSDTSRFEREYVKPIKSIPESLHTHDILYGGDQNRLDREKLVKHHSGQYRHKTAFIWDPHPQYKFTAFGHLFHLVLIQDSKFVSPDIKITRVKHNETWREPPNVKVNGCFYSGNVSGEPDSVVSVSLCDGITGYIRTTTGNYFIEPAETTDDHVTPALHTIYRAGQLAEGDKSPGQTQQSHQPEKNCGVQDNEGTGDSDTIADDDSATAEVGPFIVGGAGGPNRLTENDIFSSSTGLPYTKKTRNKRSLTSEYVVELMVVADKKMAEYHGKELHNYVLTLMSIVSKIYKDKSIGNPMHIAVVKLVVLRDVHFVENRSRMGGIAAADMLHRFCEWQTHHNDENDSSANHHDSALLLTREHVCRNHNQKKCDNTLGLAQLGTMCNVNSCAIVQDNGLSAAFTIAHELGHVLNMPHDDDNKCKDFEQQDGMHNVMSRMLDHNSHPWTWSACSRHFLTEYLEAGNGRCLQDDPSKDYLEIENQTEEKHFPGENYTGDKQCELIYGSGSKICSYMPVCQRLWCTTGSGEKDGCRTQHMPWADGTQCWSSKNWCQQGKCVPKDRNALKPVDGGWGSWQPYGECTRTCGGGVKKSYRDCTDPPPSNGGKYCTGKRVRVRSCATSDCPPGTPDFRGEQCAMFNNKTFNIADLEPDVQWLPKFGGYDEERCRLFCRVAASTAYYQLKEKVVDGTPCAPDKYDICVNGMCEKAGCDHALGSDSQLDMCGVCGGNNSSCQQVAGTHNSSSPNGYSKVLRIPAGSSNLDIRQHGHNGSSKDDNYLALVDSVTGEYVLNGNYVLSTFNKVIVYGGTTIEYSGSDAPVERINSSKPLNKDVTVELLSIGNSYAPDIEYQYTVMRDKRDIYVWALTDEWGQCDKMCSGEQTKIYVCVRKETGEEARGYCNEHDAPRTKKQPCNLHCTIKWKTVSQSECSAQCGPGTRTQSVACVQEYDKRTPSQISDTMCSHLPKPANTIPCDGKCLESRWSFTEWTPCSKTCGSGVQHREARCVNDNGEPRDETSCNESEKIITRVCGTDKCPQWSVGEWSSCSVTCGEGQIERSVWCRMDNGRVLAAEYCGSNMPATKETCSMKPCPAWTTGLWSQCSVTCGVGIVRRMVRCNVPDESACALIAKPLEEEKCTLHPCPAGVDNEIHENEILSNGHDTNFIHSNKFYAWRTDHWSSCSASCGNGYRRRTIDCINTISAKPVSWNLCKSKNQPKRVEVCTAPMCVTWRADEWKECSAECGKGFEEREVTCVSSASGKLVDETHCVVHREKPEARRLCESHKSCKPVSTWRTGSWGECSELCGGGIKERKVVCQPFDGTRELFDEEMCVEPKPSTSIPCNEQPCKGQPSYVTIAWNFGEWSKCNVTCGKGHQHRQVQCQNNDGVILAAVQCDGLVKPAAEQPCRTFVPCARPTTVATTTTTTTAATTTTTTMTMTATTEYRWKTSQWSACSATCGPGTQNRRVSCRRHGTDPGGRDTAADDQRCDAAAGRPPAAQRPCPQQRPCVFATSVAATAAAATAAADDYGWLPDVWRECSHSCGKKGRQTRRVFCFHRAAAKKVRRKHCDWAARPPRKRKCNQRRCAGHASCADILHKQSPQSAAALVDKDYVINVLGRNVSVYCHGMRSGNPVEYLTLSKDTENYSEIYEQRLKDPSTCPFNGERRQNCPCDNVPVPSSGLTVFLKIRLNITSLRVDSKDYTFSKQIKGKPVPFGEAGDCYSNSKRGCPQGRFSIDLSGTGMRISHDTTWVGKGSNTSFWVNKIEENMKIAGRCGGYCGTCVPMQGIILDVVTP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias266-291Polar residues
Compositional bias1553-1572Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

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