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A0A8M9Q859 · A0A8M9Q859_DANRE

Function

Catalytic activity

  • ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.
    EC:7.6.2.1 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATPase-coupled intramembrane lipid transporter activity
Molecular Functionmagnesium ion binding
Biological Processneuron development
Biological Processphospholipid translocation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospholipid-transporting ATPase
  • EC number

Gene names

    • Name
      atp8a2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M9Q859

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane340-361Helical
Transmembrane383-406Helical
Transmembrane911-931Helical
Transmembrane937-955Helical
Transmembrane984-1002Helical
Transmembrane1022-1041Helical
Transmembrane1053-1073Helical
Transmembrane1093-1112Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain87-144P-type ATPase N-terminal
Domain872-1122P-type ATPase C-terminal

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,152
  • Mass (Da)
    129,439
  • Last updated
    2022-08-03 v1
  • MD5 Checksum
    D2A6BFC2F6B8E7F8F12895FC3A314D9B
MYFNRRSKKIHSEGEQLVLTPLSQDSPLRQDQPLGPNMCSRLADRFEKRPACSAAGYRKAEDEMSGTTSQADPVDATARTVLLNRAQTTKYCDNHVSTAKYGILTFLPRFLYEQIRRAANAFFLFIALMQQIPDVSPTGRYTTLVPLIFILTVAGIKEIIEDYKRHKADNTVNKKKTTVLRNGAWQTIIWKQVAVGDIVKVTNGQHLPADMVIVSSSEPQAMCYTETSNLDGETNLKIRQGLSLTASFQSLEDLIALSGRLECEGPNRHLYDFTGTLRLDNHNPAPLGPDQVLLRGAQLRNTQWVVGIVVYTGHDSKLMQNSTKAPLKRSNVERVTNMQILVLFGILLVMALVSSIGAAIWNKQHTDEACWYLSRAGDISLNFAYNLLTFIILYNNLIPISLLVTLEVVKFTQALFINWDVEMYYAETDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNVMHFKKCTIAGITYGHFPDLDCDRSMEDFSHLPSTSHNSTEFDDPALIQNIEKNHPTSPQICEFLTMMAVCHTVVPEREDNQIIYQASSPDEGALVKGAKSLGFVFTARTPHSVIIEARGKEQTYELLNVLEFSSNRKRMSVIVRTPTGNLRLYCKGADNVIFERLNVTSQYKELTVAHLEQFATEGLRTLCFAYVDLEEGAYLEWLKEYNRISTVLKDRAQKLEECYELIEKNLLLLGATAIEDRLQAGVPETIATLMRADIKIWVLTGDKQETAINIGYSCRLVSHGMSLIIVNEDSLDATRATLTAHCSSLGDSLRKENELALIIDGQTLKYALSFEVRQAFLDLALSCKAVICCRVSPLQKSEIVDMVKKHVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNSSDYSIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFDRPCSQQNMIRFPQLYRITQNAEGFNTKVFWGHCINALIHSIILFWFPLKALEHDTPFDNGNSVDYLFVGNIVYTYVVVTVCLKAGMETTAWTRFSHLAVWGSMVLWMLFFAVYSAIWPTIPIAPDMLGQAGRVMQCWSFWLGLILVPTACLLKDVVWNAGRRTVRKTLLEEVQELEARAVDPGAAVLRDASGRRRP

Computationally mapped potential isoform sequences

There are 14 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9PQZ5A0A8M9PQZ5_DANREatp8a21211
A0A8M6YVQ8A0A8M6YVQ8_DANREatp8a21179
X1WCP3X1WCP3_DANREatp8a21211
A0A8M9PR00A0A8M9PR00_DANREatp8a21156
A0A8M9Q410A0A8M9Q410_DANREatp8a21177
A0A8M1RFW8A0A8M1RFW8_DANREatp8a21189
A0A8M3AP86A0A8M3AP86_DANREatp8a21152
A0A8M9P645A0A8M9P645_DANREatp8a21156
A0A8M9PX52A0A8M9PX52_DANREatp8a21189
A0A8M9Q856A0A8M9Q856_DANREatp8a21177
A0A8M3B6P3A0A8M3B6P3_DANREatp8a21177
A0A8M2B9Q6A0A8M2B9Q6_DANREatp8a21167
A0A8M2B9T5A0A8M2B9T5_DANREatp8a21177
A0A8M9PE87A0A8M9PE87_DANREatp8a21167

Keywords

Sequence databases

Similar Proteins

Disclaimer

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