A0A8M9Q4N8 · A0A8M9Q4N8_DANRE
- ProteinRNA helicase
- Geneddx3xa
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids812 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Cellular Component | P granule | |
Molecular Function | ATP binding | |
Molecular Function | hydrolase activity | |
Molecular Function | mRNA binding | |
Molecular Function | RNA helicase activity | |
Biological Process | cell differentiation | |
Biological Process | gamete generation | |
Biological Process | negative regulation of gene expression | |
Biological Process | neutrophil chemotaxis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRNA helicase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9Q4N8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 34-62 | Disordered | ||||
Sequence: RYIPPHLRNKDASKNAGNAYSSGRQSGYS | ||||||
Compositional bias | 47-62 | Polar residues | ||||
Sequence: KNAGNAYSSGRQSGYS | ||||||
Region | 242-289 | Disordered | ||||
Sequence: KSAFFNDRGASSRGRYERGGFGGGTGGNSRWVEESRDEEDWSKPMPPN | ||||||
Compositional bias | 272-289 | Basic and acidic residues | ||||
Sequence: WVEESRDEEDWSKPMPPN | ||||||
Domain | 326-354 | DEAD-box RNA helicase Q | ||||
Sequence: ESFHDVDMGEIIMGNITLSRYTRPTPVQK | ||||||
Motif | 326-354 | Q motif | ||||
Sequence: ESFHDVDMGEIIMGNITLSRYTRPTPVQK | ||||||
Domain | 357-554 | Helicase ATP-binding | ||||
Sequence: IPIIKTKRDLMACAQTGSGKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARKFAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDYCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFL | ||||||
Domain | 565-726 | Helicase C-terminal | ||||
Sequence: NITQKVVWVEENDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYREGYACTSIHGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLA | ||||||
Region | 732-777 | Disordered | ||||
Sequence: KSTNRGRPKRFSGGFGARDYRQMPGGGNTFGNRGARNTGGHGGNRG |
Sequence similarities
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length812
- Mass (Da)89,800
- Last updated2022-08-03 v1
- Checksum89449F1762F706A0
Computationally mapped potential isoform sequences
There are 15 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9QFI7 | A0A8M9QFI7_DANRE | ddx3xa | 841 | ||
A0A8M6Z8G4 | A0A8M6Z8G4_DANRE | ddx3xa | 728 | ||
B0S6P6 | B0S6P6_DANRE | ddx3xa | 709 | ||
A0A8M9Q4N5 | A0A8M9Q4N5_DANRE | ddx3xa | 840 | ||
A0A8M9PS93 | A0A8M9PS93_DANRE | ddx3xa | 840 | ||
A0A8M3B2Q5 | A0A8M3B2Q5_DANRE | ddx3xa | 708 | ||
A0A8M9QAW0 | A0A8M9QAW0_DANRE | ddx3xa | 825 | ||
A0A8M9QAW2 | A0A8M9QAW2_DANRE | ddx3xa | 792 | ||
A0A8M9QFJ5 | A0A8M9QFJ5_DANRE | ddx3xa | 713 | ||
A0A8M9QFJ0 | A0A8M9QFJ0_DANRE | ddx3xa | 813 | ||
A0A8M6Z099 | A0A8M6Z099_DANRE | ddx3xa | 728 | ||
A0A8M9QJS4 | A0A8M9QJS4_DANRE | ddx3xa | 784 | ||
A0A8M9QJR9 | A0A8M9QJR9_DANRE | ddx3xa | 821 | ||
A0A8M2BF54 | A0A8M2BF54_DANRE | ddx3xa | 693 | ||
A0A8M2BF62 | A0A8M2BF62_DANRE | ddx3xa | 729 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 47-62 | Polar residues | ||||
Sequence: KNAGNAYSSGRQSGYS | ||||||
Compositional bias | 272-289 | Basic and acidic residues | ||||
Sequence: WVEESRDEEDWSKPMPPN |
Keywords
- Technical term