A0A8M9PZI9 · A0A8M9PZI9_DANRE
- ProteinPhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- Genepck1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids630 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- GTP + L-seryl-[protein] = GDP + H+ + O-phospho-L-seryl-[protein]This reaction proceeds in the forward direction.
Cofactor
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | GTP binding | |
Molecular Function | kinase activity | |
Molecular Function | manganese ion binding | |
Molecular Function | phosphoenolpyruvate carboxykinase (GTP) activity | |
Biological Process | cellular response to dexamethasone stimulus | |
Biological Process | cellular response to glucose stimulus | |
Biological Process | cellular response to insulin stimulus | |
Biological Process | gluconeogenesis | |
Biological Process | glycerol biosynthetic process from pyruvate | |
Biological Process | hepatocyte differentiation | |
Biological Process | monoatomic ion homeostasis | |
Biological Process | oxaloacetate metabolic process | |
Biological Process | propionate catabolic process | |
Biological Process | response to glucose | |
Biological Process | response to starvation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PZI9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Monomer.
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 29-257 | Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal | ||||
Sequence: EFIDSSVSLCQPDALHICDGSEQENSTILSLLEEQGAIKRLRKYSNCWLARTDPRDVARVESKTVIVTAEQRDTVPTPTGGGVSQLGRWMCPEEWDKAMNLRFPGCMKGRVMYVIPFSMGPVGSPLSKIGVELTDSPYVVASMRIMTRMGKTVLSALGNGEFVRCLHSVGCPLPLRKPLVNNWPCNPELTLVAHIPDQRKIVSFGSGYGGNSLLGKKCFALRIASRIAK | ||||||
Domain | 261-619 | Phosphoenolpyruvate carboxykinase C-terminal P-loop | ||||
Sequence: WLAEHMLILGITNPAGQKKYFAAAFPSACGKTNLAMLKPSLPGWKVECVGDDIAWMKFDKEGNLRAINPENGFFGVAPGTSSKTNPNAMSTISCNTLFTNVAESSDGGVFWEGMDEDLPEGVTLTSWKNQPWTPEDGEPCAHPNSRFCTPAAQCPIIDPQWESPEGVPIEAIIFGGRRPQGVPLVYEAFDWAHGVFVGASMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGQYLSHWLSMEQRPGAKLPKIFHVNWFGRSSSGRFLWPGFGENIRVLEWMFGRLSGGAEARTTAVGLVPADGALNLHGLPDVEPLELFRVSQEFWMQELQEIREYFSRELNRDLPQEMQRQLELLEHR |
Sequence similarities
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length630
- Mass (Da)69,721
- Last updated2022-08-03 v1
- Checksum88E31B9C3012D8AA
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q7T3G9 | Q7T3G9_DANRE | pck1 | 630 |
Keywords
- Technical term