A0A8M9PYZ8 · A0A8M9PYZ8_DANRE
- ProteinDual specificity protein phosphatase
- GeneLOC110440191
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids199 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.
Catalytic activity
- H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 144 | Phosphocysteine intermediate | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | protein tyrosine/serine/threonine phosphatase activity |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDual specificity protein phosphatase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PYZ8
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 35-199 | Tyrosine-protein phosphatase | ||||
Sequence: GPVSLIWPSLFIGDESTARDKALLAGLGITHVVNCADGAHRINTGAQFYSDMSISYCGVEAADHPQFDLSQYFSSTASFIKAALTPNGKSDFFDLLLTNFVSDCKVLVHCAMGVSRSGALVLAFLMMCENLTLTDAIIAVRLNRDICPNSGFLKQLRALDKHLRS | ||||||
Domain | 124-178 | Tyrosine specific protein phosphatases | ||||
Sequence: SDFFDLLLTNFVSDCKVLVHCAMGVSRSGALVLAFLMMCENLTLTDAIIAVRLNR |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusComplete
- Length199
- Mass (Da)21,747
- Last updated2022-08-03 v1
- Checksum268D219DFB678B7C
Keywords
- Technical term