A0A8M9PVR1 · A0A8M9PVR1_DANRE
- Proteinprotein-tyrosine-phosphatase
- Geneptprsa
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1905 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | protein tyrosine phosphatase activity | |
Biological Process | olfactory bulb development | |
Biological Process | synaptic membrane adhesion |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameprotein-tyrosine-phosphatase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PVR1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1256-1279 | Helical | ||||
Sequence: LIWVVGPVLAVVFIICIVIAILLY |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MMPTGHLPILLSLSALLLSPLLTGSLA | ||||||
Chain | PRO_5035461372 | 28-1905 | protein-tyrosine-phosphatase | |||
Sequence: LSSPRFTKVPVDMIGVSGGVVSFVCQATGDPKPKVTWNKKGKRVNSQRIETIEFDEGAGAVLRIQPLRAPRDENVYECQAENSEGEINVQAKLSIIREDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPIDPNTSNGRIKQLRSGALQIENTEETDQGKYECVASNVEGVRYSSPANLYVRVRRVPPRFSILPTSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEMPVGRNVLELNSVRESANYTCVAMSSLGIIETVAQITVKSLPKPPGTPVVTETTATSITITWDSGNPEPVSHYIIQYRAKSPESKFETVDSITTTRYSIGGLSPNTDYEIRVSAFNTIGQGPPSEPVEARTGEQAPASPPRNIQARIISQNTVLVRWDEPDEPNGQIKGYRVYYTMDPTLPMSMWQIHNVQDSVLTTIQSLVTSETYTIRVLAFTSVGDGPFSDPIHVKVLQGVPGQPTNFQVGEVSDTGVELTWEPAFEKEGIISYELHYKEGKDGPLGKKKFAPTSSFVVDGLRPNTEYFFSLAAVSSKGIGAFTNDLAQTTSQAKPSAPPQDIKCSSSSSTVLMVSWRPPPAESQNGELAGYIVRYAVVGAGAEVSTEHVEAPTSDQILLQRLEKWTMYRVTVAASTSVGSGPESEPLLCRTDEDVPGAPPRRVEVEVLNSTAIKVMWRSLLPGKQHGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQEMVIGGLQPDTTYSITVAAYTTKGDGARSKPKLVLTKGAVPGPPFLSVNQNSESTAIIRWQPPDYVAPGLEVQGYRLQFGRKDVNPLATLEFGPQELEYSISNIHRGATYIFKVSAKSKSGFGEEATQELRVPEEVPRGYPQITEGSNITCCSVQFSWLPPVLAERNGAITEYTLSYQEAGTISGPKELRLPADENSYILNSLRPNAVYDVKIRAHTSVGPGPYSPPIQYRTVAYEADVPRNFTVKLVTKTTVLLSWKFYDSRFPYKCTIEYHRQKSDIDARMTKTLITNLRPNTTYEFRISCQDSSDGGPKHKLVARTAPHIQIRKPELDLKRESESTLTIVFPPLETKDLIKAIYVVVVPLKKGKGPMRHIKSPDELDLEELLGERRLGLHHSGTTRQLKQVDGKRPYIAASFKPSSMPPSFTLGNQMMYGSFENRALDRGQEYVLFILAELNTTGVKAFVSSPYTDPIMAPDLDPQPLESGGDGLIWVVGPVLAVVFIICIVIAILLYKNKPDSKRKESEPRTKCLLNNADITPHHPTDPVEMRRINFQTPGMMNHPPIPISELAEHTELLKANDNLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTRLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLFSYIQKLAQVEAGEHVSGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINSSFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 31-121 | Ig-like | ||||
Sequence: PRFTKVPVDMIGVSGGVVSFVCQATGDPKPKVTWNKKGKRVNSQRIETIEFDEGAGAVLRIQPLRAPRDENVYECQAENSEGEINVQAKLS | ||||||
Domain | 133-222 | Ig-like | ||||
Sequence: PNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPIDPNTSNGRIKQLRSGALQIENTEETDQGKYECVASNVEGVRYSSPANLY | ||||||
Domain | 230-312 | Ig-like | ||||
Sequence: PRFSILPTSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEMPVGRNVLELNSVRESANYTCVAMSSLGIIETVAQIT | ||||||
Domain | 319-409 | Fibronectin type-III | ||||
Sequence: PPGTPVVTETTATSITITWDSGNPEPVSHYIIQYRAKSPESKFETVDSITTTRYSIGGLSPNTDYEIRVSAFNTIGQGPPSEPVEARTGEQ | ||||||
Region | 394-415 | Disordered | ||||
Sequence: GQGPPSEPVEARTGEQAPASPP | ||||||
Domain | 414-508 | Fibronectin type-III | ||||
Sequence: PPRNIQARIISQNTVLVRWDEPDEPNGQIKGYRVYYTMDPTLPMSMWQIHNVQDSVLTTIQSLVTSETYTIRVLAFTSVGDGPFSDPIHVKVLQG | ||||||
Domain | 512-602 | Fibronectin type-III | ||||
Sequence: QPTNFQVGEVSDTGVELTWEPAFEKEGIISYELHYKEGKDGPLGKKKFAPTSSFVVDGLRPNTEYFFSLAAVSSKGIGAFTNDLAQTTSQA | ||||||
Domain | 607-703 | Fibronectin type-III | ||||
Sequence: PPQDIKCSSSSSTVLMVSWRPPPAESQNGELAGYIVRYAVVGAGAEVSTEHVEAPTSDQILLQRLEKWTMYRVTVAASTSVGSGPESEPLLCRTDED | ||||||
Domain | 708-807 | Fibronectin type-III | ||||
Sequence: PPRRVEVEVLNSTAIKVMWRSLLPGKQHGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQEMVIGGLQPDTTYSITVAAYTTKGDGARSKPKLVLTKGA | ||||||
Domain | 808-907 | Fibronectin type-III | ||||
Sequence: VPGPPFLSVNQNSESTAIIRWQPPDYVAPGLEVQGYRLQFGRKDVNPLATLEFGPQELEYSISNIHRGATYIFKVSAKSKSGFGEEATQELRVPEEVPRG | ||||||
Domain | 908-1003 | Fibronectin type-III | ||||
Sequence: YPQITEGSNITCCSVQFSWLPPVLAERNGAITEYTLSYQEAGTISGPKELRLPADENSYILNSLRPNAVYDVKIRAHTSVGPGPYSPPIQYRTVAY | ||||||
Domain | 1007-1091 | Fibronectin type-III | ||||
Sequence: VPRNFTVKLVTKTTVLLSWKFYDSRFPYKCTIEYHRQKSDIDARMTKTLITNLRPNTTYEFRISCQDSSDGGPKHKLVARTAPHI | ||||||
Region | 1285-1311 | Disordered | ||||
Sequence: SKRKESEPRTKCLLNNADITPHHPTDP | ||||||
Domain | 1350-1605 | Tyrosine-protein phosphatase | ||||
Sequence: LSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTRLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEA | ||||||
Domain | 1525-1596 | Tyrosine specific protein phosphatases | ||||
Sequence: LAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYS | ||||||
Domain | 1637-1896 | Tyrosine-protein phosphatase | ||||
Sequence: MELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINSSFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEY | ||||||
Domain | 1814-1887 | Tyrosine specific protein phosphatases | ||||
Sequence: IDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ |
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,905
- Mass (Da)212,525
- Last updated2022-08-03 v1
- ChecksumB72D7E20A71BEDCD
Computationally mapped potential isoform sequences
There are 34 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9PJX4 | A0A8M9PJX4_DANRE | ptprsa | 1945 | ||
A0A8M9PK00 | A0A8M9PK00_DANRE | ptprsa | 1502 | ||
A0A8M9PK04 | A0A8M9PK04_DANRE | ptprsa | 1512 | ||
A0A8M9PJY3 | A0A8M9PJY3_DANRE | ptprsa | 1936 | ||
A0A8M9PJY7 | A0A8M9PJY7_DANRE | ptprsa | 1928 | ||
A0A8M9PJX8 | A0A8M9PJX8_DANRE | ptprsa | 1942 | ||
A0A8M9PJZ1 | A0A8M9PJZ1_DANRE | ptprsa | 1831 | ||
A0A8M9PJZ6 | A0A8M9PJZ6_DANRE | ptprsa | 1520 | ||
A0A8M9PS70 | A0A8M9PS70_DANRE | ptprsa | 1924 | ||
A0A8M9PS75 | A0A8M9PS75_DANRE | ptprsa | 1530 | ||
A0A8M9PS80 | A0A8M9PS80_DANRE | ptprsa | 1920 | ||
A0A8M9PS86 | A0A8M9PS86_DANRE | ptprsa | 1518 | ||
A0A8M9PS56 | A0A8M9PS56_DANRE | ptprsa | 1944 | ||
A0A8M9PS58 | A0A8M9PS58_DANRE | ptprsa | 1941 | ||
A0A8M9PS65 | A0A8M9PS65_DANRE | ptprsa | 1932 | ||
A0A8M9P4J6 | A0A8M9P4J6_DANRE | ptprsa | 1923 | ||
A0A8M9P4J8 | A0A8M9P4J8_DANRE | ptprsa | 1529 | ||
A0A8M9P4K2 | A0A8M9P4K2_DANRE | ptprsa | 1901 | ||
A0A8M9P4K6 | A0A8M9P4K6_DANRE | ptprsa | 1498 | ||
A0A8M9PVP4 | A0A8M9PVP4_DANRE | ptprsa | 1942 | ||
A0A8M9PVP8 | A0A8M9PVP8_DANRE | ptprsa | 1936 | ||
A0A8M9PVQ3 | A0A8M9PVQ3_DANRE | ptprsa | 1927 | ||
A0A8M9PVQ7 | A0A8M9PVQ7_DANRE | ptprsa | 1533 | ||
A0A8M9P4I5 | A0A8M9P4I5_DANRE | ptprsa | 1944 | ||
A0A8M9P4J0 | A0A8M9P4J0_DANRE | ptprsa | 1940 | ||
A0A8M9P4J3 | A0A8M9P4J3_DANRE | ptprsa | 1929 | ||
A0A8M9PVR5 | A0A8M9PVR5_DANRE | ptprsa | 1506 | ||
A0A8M9PE85 | A0A8M9PE85_DANRE | ptprsa | 1943 | ||
A0A8M9PE90 | A0A8M9PE90_DANRE | ptprsa | 1939 | ||
A0A8M9PE92 | A0A8M9PE92_DANRE | ptprsa | 1928 | ||
A0A8M9PE98 | A0A8M9PE98_DANRE | ptprsa | 1923 | ||
A0A8M9PEA2 | A0A8M9PEA2_DANRE | ptprsa | 1524 | ||
A0A8M9PEA7 | A0A8M9PEA7_DANRE | ptprsa | 1916 | ||
A0A8M9PEB3 | A0A8M9PEB3_DANRE | ptprsa | 1513 |
Keywords
- Technical term