A0A8M9PV04 · A0A8M9PV04_DANRE

Function

Catalytic activity

Features

Showing features for binding site.

123322004006008001,0001,2001,4001,6001,8002,0002,200
TypeIDPosition(s)Description
Binding site307Ca2+ (UniProtKB | ChEBI)
Binding site646Ca2+ (UniProtKB | ChEBI)
Binding site1316Ca2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentneuronal cell body
Cellular Componentsynapse
Cellular Componentvoltage-gated calcium channel complex
Molecular Functionhigh voltage-gated calcium channel activity
Molecular Functionmetal ion binding
Molecular Functionvoltage-gated calcium channel activity
Biological Processcalcium ion import across plasma membrane
Biological Processchemical synaptic transmission
Biological Processneuromuscular synaptic transmission
Biological Processswimming behavior
Biological Processthigmotaxis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Voltage-dependent P/Q-type calcium channel subunit alpha-1A
  • Alternative names
    • Voltage-gated calcium channel subunit alpha Cav2.1

Gene names

    • Name
      cacna1ab

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M9PV04

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane220-239Helical
Transmembrane326-348Helical
Transmembrane466-485Helical
Transmembrane497-517Helical
Transmembrane592-614Helical
Transmembrane667-692Helical
Transmembrane1098-1117Helical
Transmembrane1137-1158Helical
Transmembrane1170-1189Helical
Transmembrane1232-1254Helical
Transmembrane1345-1370Helical
Transmembrane1426-1445Helical
Transmembrane1457-1479Helical
Transmembrane1491-1515Helical
Transmembrane1536-1565Helical
Transmembrane1633-1657Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for glycosylation.

TypeIDPosition(s)Description
Glycosylation272N-linked (GlcNAc...) asparagine

Keywords

Family & Domains

Features

Showing features for region, coiled coil, compositional bias, domain.

TypeIDPosition(s)Description
Region11-40Disordered
Coiled coil688-715
Region793-856Disordered
Compositional bias803-817Polar residues
Compositional bias832-852Basic residues
Region872-966Disordered
Compositional bias885-948Basic and acidic residues
Region1046-1071Disordered
Domain1795-1829Voltage-dependent calcium channel alpha-1 subunit IQ
Region1837-1861Disordered
Region1889-1984Disordered
Compositional bias1896-1912Basic and acidic residues
Compositional bias1961-1981Polar residues
Compositional bias1997-2030Basic and acidic residues
Region1997-2332Disordered
Compositional bias2064-2080Basic residues
Compositional bias2081-2108Basic and acidic residues
Compositional bias2109-2151Polar residues
Compositional bias2179-2198Pro residues
Compositional bias2233-2251Basic and acidic residues
Compositional bias2266-2280Basic residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,332
  • Mass (Da)
    266,561
  • Last updated
    2022-08-03 v1
  • Checksum
    0733A240CEF205EC
MARFGDEVPARYGGGGGGGSGQGGPGRGGSRQGGPPGAQRMYKQSMAQRARTMAIYNPIPVRQNCLTVNRSLFLFSEDNIVRKYAKKITEWPPFEWMILTTIIANCIVLALEQHLPVGDKTPLSERLEETEPYFIAIFCFESGIKILALGFAFHKGSYLRNGWNVMDFVVVLTGILSSVGSELDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGVLLFVAILMFAIIGLEFYMGKFHTTCFNTITGEMYDERPCGARTCDANNTQCQGYWLGPNYGITQFDNVLFAVLTVFQCITMEGWTDMLYYSNDALGSAWNWMYYVPLIIIGSFFMLNLVLGVLSGEFAKERERVENRSEFLKLKRQQQIERELNGYLEWICKAEEVILAEDDNDTGSRRRPTLKKNKADLLNPQEGVDHMGDSVGSPFARGSMSGKGDETPFSKKERRLRFLIRKMVKTQAFYWTVISLVALNTLCVAVVHYDQPELLSDFLYYAEFIFLGLFMSEMLIKMYGLGTRPYFHSSFNCFDCAVIVGSIFEVVWAMVKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFELGTPPTNFDTFPAAIMTVFQILTGEDWNVVMYDGIKSQGGVDKGMIFSVFFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEATTQKMALQKAKEVAEVSPLSAANLSIAAKEQQKNSKGSKSVWEQRTSEIRRQNLMTSREALYNELDAEDHWKMNYRNRPDVKTHLDRPLVVNPQENRNNNTNKPRPDDPNPQERSEEHPSRSHHHHSHHHHHHHHHTHHSSRQSLHLPELAETGFECDVEGAGEHRRPRHHQHRRRDEDGGERGRKHRDHHSRGETAGGDAEDGQEKRQRRHRHANHGDGDGRRERSRLHRNKKEGSLSTARPIQPGLPHTESQYSEDLDNLRNSSKMAIHDPDPDLYDPYYDPEQANNLLNLRGPDLHDSSLILTDSSKLEHTAIDMPPIYPSLNAKLQVNKNANTEPAKEGEKKEEEEDDGGDEEGHKRIPPFSSCFILSTTNPFRRCCHYILTLRYFEMCILSVIAMSSIALAAEDPVSQDSERNKVLRYFDYVFTGVFTFEMLIKMVVLGLILHEGSYFRDLWNFLDFVVVSGALVAFAFTGSGKGKDISIIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVVAVQLFKGRFFYCTDESKEFARDCRGEYLVYERDNEVKSQKREWKKYDFHYDNVLWALLTLFTVSTGEGWPDVLKHSVDSTYENRGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEDYSLEKNERACIDFAINAKPLTRHMPQNKQSFQYRMWQFVVSPPFEYSIMSLIALNTIILMMKYNGASDAYDKVLKNLNIVFTTFFFMESILKIIAFGVRNFFRDAWNIFDFVSVIGSITDILVTELVNNFINLSFLRLFRAARLIKLLRQGETIRILLWTFVQSFKALPYVCLLIAILFFIYAIIGMQLFGNLALDDEGAINEHNNFRTFFMALMLLFRSATGEAWHDIMLSCLGGMPCEPEEVGSECGSNVAYAYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRIWAEYDPAACGRIHYKDMYSLLRVIDPPLGLGKKCPHRVACKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKHQMDAELRKEMMAIWPNLSQKNLDLLVTPHKSATDLTVGKIYAAMMIMEYYRQSKAKKLQALREEQNRTPLMFQRMEPSPNQEGGPGLNGLPELPQEPVNSLPPEVGMNESQSWVTSRAQEMCQKSVPENWNPDRPYPDDHHDSRHNPQTVEMREFGPVGDGYSDTEPYHPMEGHGRTISMPRLSADNQRRRHRPRGSNLSTITDTSPMRRSTSSLVHGRSGRGVRLDDYSLERVVSEEGHRHAPRRRDRDRDRDRDRSHRTSERSLARYTDADTGLGTDLSTTTQSGDLPPKERERERGRAKDRRHHHHHHHHHGSVDKDRYSHERDYHRHPQDRSDRQWSRSPSEGRGHRQGSSSVSGSPVPSTSGTSTPRRGRRQLPQTPSTPRPHVTYSPAVRKPPYGSPGQGRLRSPSPRNFSPPGHEPPYHRPPSRHASPHPGSPRHASPRSPRHTSPRSPRHGRWGPPDSLEGDGTFYERDYEYERHHEPPAYEQSLSQGNPHPHSHPHPRSPRTARHGPQPHPRRMPNGYRSSSPSPHRRGPHPGPHRPPHGRGPRKGLHEQYSETDEDDWC

Computationally mapped potential isoform sequences

There are 16 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9PUZ6A0A8M9PUZ6_DANREcacna1ab2336
A0A8M9QLP2A0A8M9QLP2_DANREcacna1ab2335
A0A8M9QLP7A0A8M9QLP7_DANREcacna1ab2330
A0A8M9QLQ1A0A8M9QLQ1_DANREcacna1ab2119
A0A8M9PV10A0A8M9PV10_DANREcacna1ab2324
A0A8M9Q7A3A0A8M9Q7A3_DANREcacna1ab2336
A0A8M9Q7B0A0A8M9Q7B0_DANREcacna1ab2332
A0A8M9Q7B5A0A8M9Q7B5_DANREcacna1ab2296
F8W3Z0F8W3Z0_DANREcacna1ab2280
A0A8M9QD65A0A8M9QD65_DANREcacna1ab2331
A0A8M9QD71A0A8M9QD71_DANREcacna1ab2284
A0A8M9QD59A0A8M9QD59_DANREcacna1ab2335
A0A8M9QHR9A0A8M9QHR9_DANREcacna1ab1693
A0A8M9QHQ9A0A8M9QHQ9_DANREcacna1ab2335
A0A8M9QHR4A0A8M9QHR4_DANREcacna1ab2328
A0A8M6Z3D5A0A8M6Z3D5_DANREcacna1ab2331

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias803-817Polar residues
Compositional bias832-852Basic residues
Compositional bias885-948Basic and acidic residues
Compositional bias1896-1912Basic and acidic residues
Compositional bias1961-1981Polar residues
Compositional bias1997-2030Basic and acidic residues
Compositional bias2064-2080Basic residues
Compositional bias2081-2108Basic and acidic residues
Compositional bias2109-2151Polar residues
Compositional bias2179-2198Pro residues
Compositional bias2233-2251Basic and acidic residues
Compositional bias2266-2280Basic residues

Keywords

Sequence databases

Similar Proteins

Disclaimer

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