A0A8M9PUF9 · A0A8M9PUF9_DANRE
- ProteinTroponin T2e, cardiac isoform X4
- Genetnnt2e
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids310 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | troponin complex | |
Molecular Function | tropomyosin binding | |
Molecular Function | troponin C binding | |
Molecular Function | troponin I binding | |
Biological Process | cardiac muscle contraction | |
Biological Process | regulation of muscle contraction | |
Biological Process | sarcomere organization |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PUF9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-40 | Acidic residues | |||
Region | 1-75 | Disordered | |||
Compositional bias | 109-161 | Basic and acidic residues | |||
Region | 109-198 | Disordered | |||
Compositional bias | 176-198 | Basic and acidic residues | |||
Sequence similarities
Belongs to the troponin T family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length310
- Mass (Da)37,098
- Last updated2022-08-03 v1
- Checksum1582059C8B0D5CDE
Computationally mapped potential isoform sequences
There are 10 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9QB78 | A0A8M9QB78_DANRE | tnnt2e | 326 | ||
A0A0R4IYQ0 | A0A0R4IYQ0_DANRE | tnnt2e | 278 | ||
A0A8M9Q0H5 | A0A8M9Q0H5_DANRE | tnnt2e | 301 | ||
A0A8M9Q5W5 | A0A8M9Q5W5_DANRE | tnnt2e | 317 | ||
A0A8M9Q5W9 | A0A8M9Q5W9_DANRE | tnnt2e | 280 | ||
A8WGB3 | A8WGB3_DANRE | tnnt2e | 249 | ||
Q5RIF4 | Q5RIF4_DANRE | tnnt2e | 239 | ||
Q5RIF5 | Q5RIF5_DANRE | tnnt2e | 285 | ||
A0A8M9QB81 | A0A8M9QB81_DANRE | tnnt2e | 286 | ||
A0A8M9PH92 | A0A8M9PH92_DANRE | tnnt2e | 312 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-40 | Acidic residues | |||
Compositional bias | 109-161 | Basic and acidic residues | |||
Compositional bias | 176-198 | Basic and acidic residues | |||
Keywords
- Technical term