A0A8M9PSI1 · A0A8M9PSI1_DANRE

Function

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

114131002003004005006007008009001,0001,1001,2001,3001,400
Type
IDPosition(s)Description
Binding site107ATP (UniProtKB | ChEBI)
Active site200Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcentrosome
Cellular Componentcytoplasm
Cellular Componentcytoskeleton
Cellular Componentextracellular region
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionRho-dependent protein serine/threonine kinase activity
Molecular Functionsmall GTPase binding
Biological Processactomyosin structure organization
Biological Processcortical actin cytoskeleton organization
Biological Processembryonic morphogenesis
Biological Processepithelial cilium movement involved in determination of left/right asymmetry
Biological Processheart morphogenesis
Biological ProcessKupffer's vesicle development
Biological Processmitotic cytokinesis
Biological Processpositive regulation of centrosome duplication
Biological Processprotein phosphorylation
Biological Processregulation of actin cytoskeleton organization
Biological Processregulation of cell junction assembly
Biological ProcessRho protein signal transduction
Biological Processsmooth muscle contraction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      rock2b
    • Synonyms
      cb64
      , sb:cb64
      , si:dkey-65b13.10
      , si:dkey-65b13.7

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M9PSI1

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, coiled coil, region.

Type
IDPosition(s)Description
Domain78-340Protein kinase
Domain341-412AGC-kinase C-terminal
Coiled coil431-608
Coiled coil644-909
Coiled coil942-1007
Domain967-1035RhoBD
Coiled coil1045-1090
Domain1140-1413Protein kinase
Region1173-1209Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,413
  • Mass (Da)
    163,058
  • Last updated
    2022-08-03 v1
  • Checksum
    806FA3C71B36BF5D
MSTGAGKRIESRVRKLETLIKNQKSPLNLESLLDSVTALALDLNHPALRKNKNIDAFLSRYEKAVCNLKELQVKLDDFDRVKLIGRGAFGAVQLVRHKVSQQVYAMKQLSKFEMVKRSDSAFFWEERDIMAFSQSPWIVQLCCAFQDEKYLYLVMEFMPGGDLVTLTSNYDIPEEWAQFYTAEVVLALDAIHSLGFIHRDIKPDNMLLDRNGHLKLADFGTCMKMDSTGMVRCDTAVGTPDYISPEVLMSQGGTGYYGRECDWWSVGVFIYELLVGDTPFYSESLVGTYGKIMDHKNSLTFPDDIEMSKNAKDLICAFLSSREVRLGRTGVDEIKCHPFFKNDQWTFDTIRDTMAPVVPELSSDIDTSNFDDDIKDDPIGTETFPPPRAFAGNQLPFVGFTYFREDQLLTQQNKCSEEDIIEDHGLNHTESNDLEKRLKKLEEKFKHEMQAKEELENKCRIANQRLEKLSKDLEEEVNARQEAEDNLRSLEKEKVLLKHQRTQSVRKAGLETDRKRLLENEVSSLKEQLAELKKKNQISHLSAEKNIHLERQLEEVSAKLQAELEESERLKKAQIEAFRQSQQLELSLRELQERLAQLENSRLVLEQDKLSLQTSLELEKRERNAGSETITDLQGRIYGLEGELKHIKSSLSKAEVEKRQLQEDLTTLEKEKNKQEIDLSFKLKAVQQSLEQEEAEHKTTKARLADNNKINQSIEAKSETLKDMEHKLLEERSAKQQLENRLMQLEKENSVLDCDYKQAKHELQELRSLKENLTEQVEVLNVRVQQETQRKTLCQGDLKVQRQEINSLRSSEQQLKQELNHLLELKLTLEKQNQELSKEREESEKQLKEMKDQLEAEQYFTKLYKTQIRELKEESDEKVKLYKDAQQRIEDLQEERDSLASQLEVSLTKADSEQLARITVEEQYSDLEKEKIMKELEIKDMIARHRQDLAEKDGTINSLEESNRTLTVDVANLASEKEELNNKLKHIQQKLEKIKEEEKQMKSLTVSYEKQIQVEKTLKIQAINKLAEVMKKTDGRPHQINNTDIRRKEKEIRQLQLQLRTEKEKLNHSIIKYQREINDMQAMIAEESQVRLEMQMSLDSKDSDIERLRSQLTSLSIHSLDTTSISSIGNDLDSDEAYPVRITHSHTSESMSFTYQRSSKSVCIDTRPCRIAPRFSSDSDEEEDEEDEWRQTPALTYETPPDPEAAAAESGLEGWLSMPAKNTKRFGWDKKLCCAFQDEKYLYLVMEFMPGGDLVTLTSNYDIPEEWAQFYTAEVVLALDAIHSLGFIHRDIKPDNMLLDRNGHLKLADFGTCMKMDSTGLVSCDAAVGTPDYISPEVLMSQGGTGYYGRECDWWSVGVFIYELLVGDTPFYSESLVGTYGKIMDHKNSLTFPDDIEMSKDAKDLICAFLSSR

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9PP53A0A8M9PP53_DANRErock2b1493
A0A8M6YWK7A0A8M6YWK7_DANRErock2b1426
A0A8M9PP57A0A8M9PP57_DANRErock2b1346
A0A8M1NDD8A0A8M1NDD8_DANRErock2b1401
A0A8M3AT74A0A8M3AT74_DANRErock2b941
A0A8M9PBK6A0A8M9PBK6_DANRErock2b1478
A0A8M6YUR0A0A8M6YUR0_DANRErock2b1468
A0A8M9PH50A0A8M9PH50_DANRErock2b1471
A0A8M6Z372A0A8M6Z372_DANRErock2b1082

Keywords

Sequence databases

Similar Proteins

Disclaimer

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