A0A8M9PNA9 · A0A8M9PNA9_DANRE
- ProteinDNA helicase
- Genechd6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2951 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- ATP + H2O = ADP + H+ + phosphate
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromatin | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent chromatin remodeler activity | |
Molecular Function | chromatin binding | |
Molecular Function | DNA binding | |
Molecular Function | histone binding | |
Biological Process | chromatin remodeling | |
Biological Process | regulation of gene expression |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA helicase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PNA9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-23 | Basic and acidic residues | ||||
Sequence: MSGAGVSRRRHKEQEKMKIQKKD | ||||||
Region | 1-257 | Disordered | ||||
Sequence: MSGAGVSRRRHKEQEKMKIQKKDKQMSASYVLKHTPSAAASNASDQNAQTTFPIGHLGKEQLRIIGGPPNHCMAHPKHSGPAVSSHSLRPSMINNEEDDGGGGTKVKKKRRKKDKKESEWHEDGQSNAKPKRREQKEGKEILPRKTKTAKEQKDHKKRDAKAQKEVKKVKKGQDVKVKTLAKNQCATHTPSKRGRKPKEQGAMPPEKKKKGKRKSDAVLEMVESDDTASLSTLATGGEESTDPMDNTKRRSGRQVKR | ||||||
Compositional bias | 30-54 | Polar residues | ||||
Sequence: YVLKHTPSAAASNASDQNAQTTFPI | ||||||
Compositional bias | 115-177 | Basic and acidic residues | ||||
Sequence: KKESEWHEDGQSNAKPKRREQKEGKEILPRKTKTAKEQKDHKKRDAKAQKEVKKVKKGQDVKV | ||||||
Compositional bias | 192-221 | Basic and acidic residues | ||||
Sequence: KRGRKPKEQGAMPPEKKKKGKRKSDAVLEM | ||||||
Compositional bias | 225-241 | Polar residues | ||||
Sequence: DDTASLSTLATGGEEST | ||||||
Compositional bias | 242-257 | Basic and acidic residues | ||||
Sequence: DPMDNTKRRSGRQVKR | ||||||
Domain | 305-369 | Chromo | ||||
Sequence: NIIEKILSVRTVNKEMAPDEPPEEMEEFYVKYRNFSYLHCKWATLEELEKDPRIHQKIKRFRNKQ | ||||||
Domain | 389-455 | Chromo | ||||
Sequence: IEVDRVLEIAITTDTETGEEVTHYLVKWCSLSYEESTWELQEDVDPVKIKEFEELKKVPEMKHVERP | ||||||
Domain | 487-661 | Helicase ATP-binding | ||||
Sequence: LFNWYNRKNCILADEMGLGKTIQSITFLYEIFLMGLRGPFLIIAPLSTITNWEREFRTWTEMNVIVYHGSQISRQMILQYEMYHRDEQGNIMSGEFKFQGVITTFEMIMADCPELKKINWRCVVIDEAHRLKNRNCKLLEGLKLMNLEHKVLLTGTPLQNSVEELFSLLNFLEPS | ||||||
Domain | 801-970 | Helicase C-terminal | ||||
Sequence: LIDKLLPKLLAGGHKVLVFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFSKVDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSLNGVQQLSKMEVEDLL | ||||||
Region | 1184-1203 | Disordered | ||||
Sequence: LQNHSGLSAPVPRGRKGKKL | ||||||
Region | 1337-1368 | Disordered | ||||
Sequence: EQSGAETPSDAPDGISKSDEIKEENHVKSEEL | ||||||
Compositional bias | 1349-1368 | Basic and acidic residues | ||||
Sequence: DGISKSDEIKEENHVKSEEL | ||||||
Region | 1674-1727 | Disordered | ||||
Sequence: PQPPEYHPTPAHHTPTQLVHTHGHHQSSEASEPGSSLGIGSGNREGFLDCPPLD | ||||||
Compositional bias | 1687-1711 | Polar residues | ||||
Sequence: TPTQLVHTHGHHQSSEASEPGSSLG | ||||||
Region | 1851-1886 | Disordered | ||||
Sequence: SFLDAPQPDDGQEGDETLTDCLSMPSSDSQSNPVEP | ||||||
Compositional bias | 1869-1886 | Polar residues | ||||
Sequence: TDCLSMPSSDSQSNPVEP | ||||||
Region | 1905-2039 | Disordered | ||||
Sequence: DQTDLSASLPEYVPPPPLGLPDVSLDQADPLNEEQEDKLSDSNITPCVPSPEEEAESMGFNFEKEDLSPDSQKTKDTQDDMPSIESPSENCLDESQKEDCKVPFDDSIERDLKDPCEMALEEPYEKPLREPEKVP | ||||||
Compositional bias | 1961-1986 | Basic and acidic residues | ||||
Sequence: SMGFNFEKEDLSPDSQKTKDTQDDMP | ||||||
Compositional bias | 1995-2039 | Basic and acidic residues | ||||
Sequence: CLDESQKEDCKVPFDDSIERDLKDPCEMALEEPYEKPLREPEKVP | ||||||
Region | 2446-2498 | Disordered | ||||
Sequence: PEQQSGAESISHPVVSSTSSQSECPPATPTTLSSHSATPSPAAAAATETLSAS | ||||||
Region | 2621-2651 | Disordered | ||||
Sequence: ILSGPVSRDPGPRRRGRRPRTEMPKAPELPA | ||||||
Compositional bias | 2630-2644 | Basic and acidic residues | ||||
Sequence: PGPRRRGRRPRTEMP | ||||||
Compositional bias | 2763-2786 | Polar residues | ||||
Sequence: TSTSVDSSDTAPPQDNASSPVSSE | ||||||
Region | 2763-2823 | Disordered | ||||
Sequence: TSTSVDSSDTAPPQDNASSPVSSEKGNKEDAKQGGEDKKTSASVSTAAATSSSNSSSITST | ||||||
Compositional bias | 2800-2823 | Polar residues | ||||
Sequence: KKTSASVSTAAATSSSNSSSITST | ||||||
Region | 2859-2951 | Disordered | ||||
Sequence: MPAADSTGSPKRKRKKVREEGLVEGSGILGTQIDGEESKGVKDEQTPELKSQEARVEENGPDVDLAPTNLIKAPSEDKRTEENEKTEQDAQGD | ||||||
Compositional bias | 2866-2880 | Basic and acidic residues | ||||
Sequence: GSPKRKRKKVREEGL | ||||||
Compositional bias | 2894-2918 | Basic and acidic residues | ||||
Sequence: EESKGVKDEQTPELKSQEARVEENG | ||||||
Compositional bias | 2932-2951 | Basic and acidic residues | ||||
Sequence: PSEDKRTEENEKTEQDAQGD |
Sequence similarities
Belongs to the SNF2/RAD54 helicase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,951
- Mass (Da)331,116
- Last updated2022-08-03 v1
- Checksum38396C69B5933888
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8N7T870 | A0A8N7T870_DANRE | chd6 | 2953 | ||
X1WCW5 | X1WCW5_DANRE | chd6 | 2935 | ||
A0A8M3ATN8 | A0A8M3ATN8_DANRE | chd6 | 2949 | ||
A0A8M3BAM2 | A0A8M3BAM2_DANRE | chd6 | 2952 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-23 | Basic and acidic residues | ||||
Sequence: MSGAGVSRRRHKEQEKMKIQKKD | ||||||
Compositional bias | 30-54 | Polar residues | ||||
Sequence: YVLKHTPSAAASNASDQNAQTTFPI | ||||||
Compositional bias | 115-177 | Basic and acidic residues | ||||
Sequence: KKESEWHEDGQSNAKPKRREQKEGKEILPRKTKTAKEQKDHKKRDAKAQKEVKKVKKGQDVKV | ||||||
Compositional bias | 192-221 | Basic and acidic residues | ||||
Sequence: KRGRKPKEQGAMPPEKKKKGKRKSDAVLEM | ||||||
Compositional bias | 225-241 | Polar residues | ||||
Sequence: DDTASLSTLATGGEEST | ||||||
Compositional bias | 242-257 | Basic and acidic residues | ||||
Sequence: DPMDNTKRRSGRQVKR | ||||||
Compositional bias | 1349-1368 | Basic and acidic residues | ||||
Sequence: DGISKSDEIKEENHVKSEEL | ||||||
Compositional bias | 1687-1711 | Polar residues | ||||
Sequence: TPTQLVHTHGHHQSSEASEPGSSLG | ||||||
Compositional bias | 1869-1886 | Polar residues | ||||
Sequence: TDCLSMPSSDSQSNPVEP | ||||||
Compositional bias | 1961-1986 | Basic and acidic residues | ||||
Sequence: SMGFNFEKEDLSPDSQKTKDTQDDMP | ||||||
Compositional bias | 1995-2039 | Basic and acidic residues | ||||
Sequence: CLDESQKEDCKVPFDDSIERDLKDPCEMALEEPYEKPLREPEKVP | ||||||
Compositional bias | 2630-2644 | Basic and acidic residues | ||||
Sequence: PGPRRRGRRPRTEMP | ||||||
Compositional bias | 2763-2786 | Polar residues | ||||
Sequence: TSTSVDSSDTAPPQDNASSPVSSE | ||||||
Compositional bias | 2800-2823 | Polar residues | ||||
Sequence: KKTSASVSTAAATSSSNSSSITST | ||||||
Compositional bias | 2866-2880 | Basic and acidic residues | ||||
Sequence: GSPKRKRKKVREEGL | ||||||
Compositional bias | 2894-2918 | Basic and acidic residues | ||||
Sequence: EESKGVKDEQTPELKSQEARVEENG | ||||||
Compositional bias | 2932-2951 | Basic and acidic residues | ||||
Sequence: PSEDKRTEENEKTEQDAQGD |
Keywords
- Technical term