A0A8M9PMM8 · A0A8M9PMM8_DANRE
- ProteinAcyl-coenzyme A thioesterase THEM4
- Genethem4
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids250 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H+This reaction proceeds in the forward direction.
- (9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H+This reaction proceeds in the forward direction.
- H2O + octanoyl-CoA = CoA + H+ + octanoateThis reaction proceeds in the forward direction.
- H2O + tetradecanoyl-CoA = CoA + H+ + tetradecanoateThis reaction proceeds in the forward direction.
- decanoyl-CoA + H2O = CoA + decanoate + H+This reaction proceeds in the forward direction.
- dodecanoyl-CoA + H2O = CoA + dodecanoate + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrial intermembrane space | |
Cellular Component | ruffle membrane | |
Molecular Function | hydrolase activity | |
Biological Process | apoptotic process | |
Biological Process | lipid metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcyl-coenzyme A thioesterase THEM4
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PMM8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Peripheral membrane protein
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 145-217 | Thioesterase | ||||
Sequence: GHVHGGAIATMIDTVTGTLAGYLSGPSVTANLNINYRSPVPLGSVVIIHCALDRIEGRKTFITCKVTSTDESK |
Sequence similarities
Belongs to the THEM4/THEM5 thioesterase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length250
- Mass (Da)27,888
- Last updated2022-08-03 v1
- ChecksumF49EF5B8E118BFD3
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9NZE6 | A0A8M9NZE6_DANRE | them4 | 260 | ||
A1L2E6 | A1L2E6_DANRE | them4 | 222 | ||
F8W5N5 | F8W5N5_DANRE | them4 | 236 | ||
A0A8M9NZE8 | A0A8M9NZE8_DANRE | them4 | 200 |
Keywords
- Technical term