A0A8M9PJM4 · A0A8M9PJM4_DANRE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

111921002003004005006007008009001,0001,100
TypeIDPosition(s)Description
Binding site251Ca2+ 2 (UniProtKB | ChEBI)
Binding site251Ca2+ 1 (UniProtKB | ChEBI)
Binding site343Ca2+ 1 (UniProtKB | ChEBI)
Binding site390Zn2+ (UniProtKB | ChEBI); catalytic
Active site391
Binding site394Zn2+ (UniProtKB | ChEBI); catalytic
Binding site400Zn2+ (UniProtKB | ChEBI); catalytic
Binding site447Ca2+ 1 (UniProtKB | ChEBI)
Binding site450Ca2+ 2 (UniProtKB | ChEBI)
Binding site450Ca2+ 1 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular matrix
Cellular Componentextracellular region
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processextracellular matrix organization
Biological Processlymphangiogenesis
Biological Processprotein processing

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform X1

Gene names

    • Name
      adamts3

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M9PJM4

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_503544236421-1192
Disulfide bond325↔374
Disulfide bond368↔447
Disulfide bond407↔433
Disulfide bond474↔499
Disulfide bond485↔508
Disulfide bond494↔527
Disulfide bond521↔532
Disulfide bond555↔592
Disulfide bond559↔597
Disulfide bond570↔582

Keywords

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain248-452Peptidase M12B
Domain1028-1071PLAC
Compositional bias1107-1137Polar residues
Region1107-1192Disordered
Compositional bias1175-1192Polar residues

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,192
  • Mass (Da)
    134,921
  • Last updated
    2022-08-03 v1
  • Checksum
    1385783A6E35B50B
MVVLSLRLLIVGVVVSLTSAHLAGEIIDKEDLLKNRLKEYGLITPISTDAEGHFLSHFLSANHKQRVKRDVLEGSAPAPDRLFFNITVFGKEFHLRLHPNQRLVAPGAMVEWHDDIEIAGNATDNRTHFERILKRELLKTDCTFIGDITDVPGASVAINNCDGLAGMIRTDSDEYFIEPLEQGTQEHEERGRVHVVYRRSAVLQTPSDISLDYQPIEPELDTPRMLDNIAKQVNKTVRRRRHAGDEDYNIEILLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLEVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAFVQQKEDPEHSEHHDHAIFLTRQGFGPTGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSMCSGQELKRYIHSYDCLLDDPFKHDWPQLPELPGINYSMDEQCRFDFGVGYKICTSFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKNANQVKQDGAWGAWSKYGSCSRSCGMGVRFRTRQCNNPVPSNGGQDCPGVNYEYQLCNTDDCPKHFEDFRAQQCQLRNSHFEYQNAKHHWLPYEHPDANKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDREIGSNKVEDKCGVCGGDNSHCRTVKGTFTRVPKKAGKTRGAFLLPKGARNVYLNETADSRNVMGYLKMFLIPPGARHVIIQEHEASPQILAIKNQATGHYVLNGKGEDARSRRFIEMGVEWDYLVEEDVETLHTDGPLNDAIVVLIIPKDNETRSTLMYKYIIHEDSVPLNNNNVIQEDTYEWALKSWSQCSRPCAGGFQYTKYGCRKKGDNKMVHRGYCDVNKKPKPIRRMCNLQDCTQPQWITEEWEHCTKTCGSLGYQIRTVRCVQFLHEGTNRSIHSKYCNGEKPEMRRACNRVACPAQWRTGAWSECSVSCGEGVSRRLVTCRIGDQCTGEKPESQKPCRPRPCHDEPCGGDKSIFCQMEVLARYCSIPGYNKLCCESCSRRSGTFAPLLHEAAETEEELRFGSASQLLETLSAAANGSLKVPQQHQRGSTSQGQFSKQAATPPPRKHNTENSKTQKRLKPSTRNLPALSIHSSWSEDGVKDAPMQLESFQESQWPTTSSEVER

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
S5RVW8S5RVW8_DANREadamts31164
A0A8M6Z0H1A0A8M6Z0H1_DANREadamts3802

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1107-1137Polar residues
Compositional bias1175-1192Polar residues

Keywords

Sequence databases

Similar Proteins

Disclaimer

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