A0A8M9PJA4 · A0A8M9PJA4_DANRE
- ProteinE3 ubiquitin-protein ligase UBR5 isoform X7
- Geneubr5
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2793 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 2762 | Glycyl thioester intermediate | |||
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | RNA binding | |
Molecular Function | ubiquitin binding | |
Molecular Function | ubiquitin-ubiquitin ligase activity | |
Molecular Function | zinc ion binding | |
Biological Process | positive regulation of canonical Wnt signaling pathway | |
Biological Process | protein polyubiquitination |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PJA4
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, zinc finger.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 79-164 | Disordered | |||
Compositional bias | 316-331 | Basic and acidic residues | |||
Region | 316-336 | Disordered | |||
Region | 567-636 | Disordered | |||
Compositional bias | 571-590 | Basic and acidic residues | |||
Compositional bias | 599-620 | Polar residues | |||
Region | 987-1067 | Disordered | |||
Compositional bias | 1005-1023 | Pro residues | |||
Compositional bias | 1036-1060 | Polar residues | |||
Domain | 1167-1235 | UBR-type | |||
Zinc finger | 1167-1235 | UBR-type | |||
Region | 1505-1730 | Disordered | |||
Compositional bias | 1516-1541 | Polar residues | |||
Compositional bias | 1553-1567 | Acidic residues | |||
Compositional bias | 1612-1641 | Polar residues | |||
Compositional bias | 1650-1675 | Polar residues | |||
Compositional bias | 1689-1730 | Polar residues | |||
Region | 1847-1876 | Disordered | |||
Region | 1975-2012 | Disordered | |||
Compositional bias | 1987-2006 | Basic and acidic residues | |||
Region | 2106-2130 | Disordered | |||
Region | 2320-2339 | Disordered | |||
Region | 2364-2385 | Disordered | |||
Domain | 2371-2448 | PABC | |||
Region | 2465-2494 | Disordered | |||
Compositional bias | 2466-2485 | Basic and acidic residues | |||
Domain | 2509-2793 | HECT | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,793
- Mass (Da)307,490
- Last updated2022-08-03 v1
- Checksum62A815750786CAAD
Computationally mapped potential isoform sequences
There are 8 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9PJ96 | A0A8M9PJ96_DANRE | ubr5 | 2833 | ||
A0A8M9PM86 | A0A8M9PM86_DANRE | ubr5 | 2822 | ||
A0A8M1NV16 | A0A8M1NV16_DANRE | ubr5 | 2794 | ||
A0A8M9P7S4 | A0A8M9P7S4_DANRE | ubr5 | 2828 | ||
A0A8M2B4T2 | A0A8M2B4T2_DANRE | ubr5 | 2816 | ||
A0A8M2B598 | A0A8M2B598_DANRE | ubr5 | 2822 | ||
A0A8M9NZ45 | A0A8M9NZ45_DANRE | ubr5 | 2832 | ||
A0A8M9PCY7 | A0A8M9PCY7_DANRE | ubr5 | 2827 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 316-331 | Basic and acidic residues | |||
Compositional bias | 571-590 | Basic and acidic residues | |||
Compositional bias | 599-620 | Polar residues | |||
Compositional bias | 1005-1023 | Pro residues | |||
Compositional bias | 1036-1060 | Polar residues | |||
Compositional bias | 1516-1541 | Polar residues | |||
Compositional bias | 1553-1567 | Acidic residues | |||
Compositional bias | 1612-1641 | Polar residues | |||
Compositional bias | 1650-1675 | Polar residues | |||
Compositional bias | 1689-1730 | Polar residues | |||
Compositional bias | 1987-2006 | Basic and acidic residues | |||
Compositional bias | 2466-2485 | Basic and acidic residues | |||
Keywords
- Technical term