A0A8M9PJA4 · A0A8M9PJA4_DANRE

Function

Features

Showing features for active site.

127932004006008001,0001,2001,4001,6001,8002,0002,2002,4002,600
TypeIDPosition(s)Description
Active site2762Glycyl thioester intermediate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionRNA binding
Molecular Functionubiquitin binding
Molecular Functionubiquitin-ubiquitin ligase activity
Molecular Functionzinc ion binding
Biological Processpositive regulation of canonical Wnt signaling pathway
Biological Processprotein polyubiquitination

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • E3 ubiquitin-protein ligase UBR5 isoform X7

Gene names

    • Name
      ubr5
    • Synonyms
      edd1
      , wu:fa16c12

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M9PJA4

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain, zinc finger.

Type
IDPosition(s)Description
Region79-164Disordered
Compositional bias316-331Basic and acidic residues
Region316-336Disordered
Region567-636Disordered
Compositional bias571-590Basic and acidic residues
Compositional bias599-620Polar residues
Region987-1067Disordered
Compositional bias1005-1023Pro residues
Compositional bias1036-1060Polar residues
Domain1167-1235UBR-type
Zinc finger1167-1235UBR-type
Region1505-1730Disordered
Compositional bias1516-1541Polar residues
Compositional bias1553-1567Acidic residues
Compositional bias1612-1641Polar residues
Compositional bias1650-1675Polar residues
Compositional bias1689-1730Polar residues
Region1847-1876Disordered
Region1975-2012Disordered
Compositional bias1987-2006Basic and acidic residues
Region2106-2130Disordered
Region2320-2339Disordered
Region2364-2385Disordered
Domain2371-2448PABC
Region2465-2494Disordered
Compositional bias2466-2485Basic and acidic residues
Domain2509-2793HECT

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,793
  • Mass (Da)
    307,490
  • Last updated
    2022-08-03 v1
  • Checksum
    62A815750786CAAD
MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNCNSHPHLIPLEQAKLKQCVVGPNHAGFLLEDGRICRISFAVQPDRLELGKPDGNDGTRWSSGVNGGGSGGGGSSGGGAGGGSGSGGGAGGGTGGGGSSGRSSTAARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSELLRERESVLRLRERRWLDGASFDAERGSTSREGEPSLDKKSVPLQSPVTLGEELQWWPDKDYVTKFVSIGALYSELVAVSTKGELYQWKWNEPEPYRNAQNPSIHHPRVPFLGLTNEKITHLSANSIRATVATENNKVATWVDETLSTVAAKLEHGAQTFPELQGERIVSLHCCALYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSIPNITVGTQVCLRNNPLYHAGAVAFSVNAGIPKVGVLLESVWNMNDSCRFQLRSPESLKNMEKNTKTQETKTESKPELVKTEMGPPPSPASTCSDTSSIASSASLPYKRRRSTPAPKEEEKVNEEQWPLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGTSSSVSSQSAAPTDSDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIPEKAEILAVNVDSKGVHAVLKTGSWVRYCVFDLATGKAEQENHFPTSNLAFLGQSERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPIASLGMGVHSLANLPSNSTIKKKAAIIIMAVEKQTLMQHVLRCDYEACRQYLISLEQAMLLEQNPHALDTLLGHRCDGNRNVLHACVSVCFPVSNKETKEEEEAERSERNTFAERLSAVEAIANAISVVSSNSSGNRTGSSSSRGLRLREMMRRSLRAAGLGRHESGPSSSDHQDPVSPPIAPPSWVPDPPPMDPDGDIDFILAPAVGSLTTASTGTSQGPSTSTIPGPSSEPSVVESKDRKANAHLILKLMCDSIVLRPHLRELLSAKDARGMTPFMLAVSGRAYPAAITVLEAAQKIAKGEPGLGEKEDTASVFMEMICPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKAARLDLLYRLLTTTNLVTTPNSRGEHILLFLVQTVARQSVEHCQYRPPRIREDRNRKAASAEDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIAHLLPEEQMYLNQQSGTIRLDCFTHCLIVKCAPDITFIDTLLGTLVKELQNKYTPGRREEAINVTRRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCRRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAVQGSEELFSVEPLPPRPSPDQSSSSSQSASSYIIRNPQPRRSSQSQTARGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDDQEEQGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQSDDVDQETFLLDEPLERTTGSAHANSAAQAPRSMQWAVRTTPSQRSGGGAPSSSSAPAASSTGLIYIDPSNLRRSSAISTSAAAAAAALEASNSSSYLTSASSLARAYSIVIRQISDLMSLIPKYNHLVYSQYPAAVKLTYQDAVNLQNFVEDKLIPTWNWMVSIMDSTEAQLRYGSALSSAGDPGHPSHPLHASQHAGRRERMTAREEASLRTLEGRRRAATLLTARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNLQTTLDTTQIDRKRNRELLELGLDNEDSEHENDEDTNQSSTLQDKDEEPVPAETGQHHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSYMASKGLTDLTVDMNCLQILPTKMSYSANMKNVMSMESRQRGGEEQPVAEQEMDVSKPGPSPHDLAAQLKSSLLAEIGLTESDGPPLPTFIPHCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNLQSRDLALEVDRDREQLIQQTMRQLNAHFGRRCTTTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNDKLPNLDCVQSVSKGMQASNLMQRLRNRDRERERRSGGLRAASRRDRDSLKRLFAVFDCRDSRRQLSIDTRPFRPASEGNPSDEPEPLPAHRQALGERLYPRVHAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVEEAMELLITHGRENGADSILDLGLLDTPEKAQQENRKRHGSTRSVVDMELDDPDDGDDNAPLFYQPGKRGFYSPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLIRHSQTEEAEAVFAAMDLAFAIDLCKEEGAGQVELLSGGVNMPVTPLNVYEYVRRYAEHRMLVVAEQPLHAMRKGLLDVLPKNALEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9PJ96A0A8M9PJ96_DANREubr52833
A0A8M9PM86A0A8M9PM86_DANREubr52822
A0A8M1NV16A0A8M1NV16_DANREubr52794
A0A8M9P7S4A0A8M9P7S4_DANREubr52828
A0A8M2B4T2A0A8M2B4T2_DANREubr52816
A0A8M2B598A0A8M2B598_DANREubr52822
A0A8M9NZ45A0A8M9NZ45_DANREubr52832
A0A8M9PCY7A0A8M9PCY7_DANREubr52827

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias316-331Basic and acidic residues
Compositional bias571-590Basic and acidic residues
Compositional bias599-620Polar residues
Compositional bias1005-1023Pro residues
Compositional bias1036-1060Polar residues
Compositional bias1516-1541Polar residues
Compositional bias1553-1567Acidic residues
Compositional bias1612-1641Polar residues
Compositional bias1650-1675Polar residues
Compositional bias1689-1730Polar residues
Compositional bias1987-2006Basic and acidic residues
Compositional bias2466-2485Basic and acidic residues

Keywords

Sequence databases

Similar Proteins

Disclaimer

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