A0A8M9PIB5 · A0A8M9PIB5_DANRE
- ProteinNeurexin 2a isoform X8
- Genenrxn2a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1638 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | synapse | |
Molecular Function | metal ion binding | |
Biological Process | axon extension involved in axon guidance | |
Biological Process | chemical synaptic transmission | |
Biological Process | motor neuron axon guidance | |
Biological Process | neuromuscular junction development |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PIB5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Presynaptic cell membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1563-1583 | Helical | ||||
Sequence: MVVGIVAAAALCILILLYAMY |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-28 | |||||
Sequence: MMTRKWRCVKLSPAFVWLGLVVLSVTTA | ||||||
Chain | PRO_5035439513 | 29-1638 | ||||
Sequence: LEFDGLPGQWVRYGPWEAGATGELSFTMKTNISKAIVLYLDDGGNCDFLELLINDGRLQLRFAIHCGEPASLHMETHISDERWHRVLLTRNYRETMLVMDGESKVAEVKSKRREMMVASDLYVGGIPPDVRLSALTSSTVKYEPPFRGLIANLKLGETAPALLDSQGVKNDLDYLCTKQNPCSNGGRCSIQGSEVLCDCSNTGYKGKYCTEVLQQVLGGLAHLTLKSQAPGAAPLMATPAAGDPKSGQVESVATFKGNEFFSYDLSQKPIQSSTDEITLSFRTLQRNGLLLHTGKSADYVNLSLKSGAVCLVINLGSGAFEALVEPSDGKFNDNAWHAVRVSRNLRQRAGVGLPTVNKLHYMQVTISVDGLLTTTGYTQEDYTMLGSDDFFYVGGSPNTADLPGSPVSNNFMGCLKDVVYTNNEFRLELSHLAELRDPKVTLHGDLTFRCEDVAALDPVSFDAPTAYVTLPRWNGKKAGSVSFDFRTTEPNGLLLFSHGRPQGSKDHRPRVDFFAMELLDGFLHLLMDMGSGSIKIKVGNKKVNDGEWCHVDFQREGRKGSISVNGRSLPFSTNEGSEILDLDGEMYLGGLPENSGDLSLPPEVWTARLRLGFVGCVRDLFVDGRSKDLRRLAELQSAPGVSSFCTRETHRRCSSEPCVHGGRCREGWNRHVCDCTGTGYMGPNCEMESAVLSYDGSMFLKVLMPHAAHSEAEDVSLRFMSQRAYGLLMATTSKESADTLRLELDGGRVKLTVNLDCIGIDCNLSKGPETLFAGHKLNDNEWHSVKVVRRGKSLQLSVDNVTVEGQMSGAHTQLEFHHIETGIMTERRFISVMPSNFIGHLQGLSFNGMPYLDQCKNGDISYCELNARFGMRRIVADPVSFRNRASYVALSTLQAYASMHLFFQFKTTSPDGLILFNSGDGSDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPLNDNQWHNVMVSRDDSNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGVGKSMYNSLPKLIASRDGYQGCLASVDLNGRLSDLIADALHRVGQVERGCEAGPGTTCTEDSCSNQGVCLQQWEGFTCDCTMTTYGGPLCSDPGTTYIFGRGGALITYTWAPNDRPSTRADRLAVGFSTQQSDAILVQVESSQGLGDYLQLHIEQGKVGVIFNVGTDDITIDEPAVTVNDGKYHVVRFTRSGGNATLQVDNQPVIERFPSGRQLTIFNSQAAIKVGGQDKGRPFQGQISGLYYNGLQVLKLAAEGDPNVQVAGNLRLVGDAPSVLSTETTSATPPAAADMSTTIMETTTTMATTTTRRQRSPSLKDSITQNSDDLLVASAECPSDDEDLEECEPGTGGELVLPIITVDTQDPISMATRYPAIPAPPTSLTPLQTTKESLILSDPRPPCPPDQEDCGDPMEVSAFGSGEMTESDDEDFNRNSPMVTDRTVLPPPPGVGKSGHGDHRPPVPAPTTHPNQLHIPAGKMNTRDQVLLPPVPSSRHTPGLTYPPDFPHVPTAHPTDLMEKGRPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNSGSESNGAVVKEKTPSTTAAVAKTTTKGKKNKDKEYYV |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 28-204 | Laminin G | ||||
Sequence: ALEFDGLPGQWVRYGPWEAGATGELSFTMKTNISKAIVLYLDDGGNCDFLELLINDGRLQLRFAIHCGEPASLHMETHISDERWHRVLLTRNYRETMLVMDGESKVAEVKSKRREMMVASDLYVGGIPPDVRLSALTSSTVKYEPPFRGLIANLKLGETAPALLDSQGVKNDLDYLC | ||||||
Domain | 200-238 | EGF-like | ||||
Sequence: LDYLCTKQNPCSNGGRCSIQGSEVLCDCSNTGYKGKYCT | ||||||
Domain | 280-478 | Laminin G | ||||
Sequence: VATFKGNEFFSYDLSQKPIQSSTDEITLSFRTLQRNGLLLHTGKSADYVNLSLKSGAVCLVINLGSGAFEALVEPSDGKFNDNAWHAVRVSRNLRQRAGVGLPTVNKLHYMQVTISVDGLLTTTGYTQEDYTMLGSDDFFYVGGSPNTADLPGSPVSNNFMGCLKDVVYTNNEFRLELSHLAELRDPKVTLHGDLTFRC | ||||||
Domain | 485-673 | Laminin G | ||||
Sequence: DPVSFDAPTAYVTLPRWNGKKAGSVSFDFRTTEPNGLLLFSHGRPQGSKDHRPRVDFFAMELLDGFLHLLMDMGSGSIKIKVGNKKVNDGEWCHVDFQREGRKGSISVNGRSLPFSTNEGSEILDLDGEMYLGGLPENSGDLSLPPEVWTARLRLGFVGCVRDLFVDGRSKDLRRLAELQSAPGVSSFC | ||||||
Domain | 677-714 | EGF-like | ||||
Sequence: THRRCSSEPCVHGGRCREGWNRHVCDCTGTGYMGPNCE | ||||||
Domain | 717-891 | Laminin G | ||||
Sequence: SAVLSYDGSMFLKVLMPHAAHSEAEDVSLRFMSQRAYGLLMATTSKESADTLRLELDGGRVKLTVNLDCIGIDCNLSKGPETLFAGHKLNDNEWHSVKVVRRGKSLQLSVDNVTVEGQMSGAHTQLEFHHIETGIMTERRFISVMPSNFIGHLQGLSFNGMPYLDQCKNGDISYC | ||||||
Domain | 905-1080 | Laminin G | ||||
Sequence: DPVSFRNRASYVALSTLQAYASMHLFFQFKTTSPDGLILFNSGDGSDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPLNDNQWHNVMVSRDDSNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGVGKSMYNSLPKLIASRDGYQGCLASVDLNGRLSDLIADALHRVGQVERGC | ||||||
Domain | 1084-1121 | EGF-like | ||||
Sequence: PGTTCTEDSCSNQGVCLQQWEGFTCDCTMTTYGGPLCS | ||||||
Domain | 1125-1295 | Laminin G | ||||
Sequence: TTYIFGRGGALITYTWAPNDRPSTRADRLAVGFSTQQSDAILVQVESSQGLGDYLQLHIEQGKVGVIFNVGTDDITIDEPAVTVNDGKYHVVRFTRSGGNATLQVDNQPVIERFPSGRQLTIFNSQAAIKVGGQDKGRPFQGQISGLYYNGLQVLKLAAEGDPNVQVAGNL | ||||||
Region | 1445-1504 | Disordered | ||||
Sequence: GSGEMTESDDEDFNRNSPMVTDRTVLPPPPGVGKSGHGDHRPPVPAPTTHPNQLHIPAGK | ||||||
Region | 1593-1638 | Disordered | ||||
Sequence: YQVDQSRNSGSESNGAVVKEKTPSTTAAVAKTTTKGKKNKDKEYYV | ||||||
Compositional bias | 1594-1625 | Polar residues | ||||
Sequence: QVDQSRNSGSESNGAVVKEKTPSTTAAVAKTT |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,638
- Mass (Da)178,320
- Last updated2022-08-03 v1
- Checksum4664791C7BC81A0A
Computationally mapped potential isoform sequences
There are 17 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A1XQX4 | A1XQX4_DANRE | nrxn2a | 1670 | ||
A0A8M9PQH6 | A0A8M9PQH6_DANRE | nrxn2a | 1659 | ||
A0A8M9PQI0 | A0A8M9PQI0_DANRE | nrxn2a | 1478 | ||
A0A8M9P3C3 | A0A8M9P3C3_DANRE | nrxn2a | 1658 | ||
A0A8M9P3C5 | A0A8M9P3C5_DANRE | nrxn2a | 1468 | ||
A0A8M3ALL4 | A0A8M3ALL4_DANRE | nrxn2a | 1492 | ||
A0A8M3AMB4 | A0A8M3AMB4_DANRE | nrxn2a | 618 | ||
B7ZCV1 | B7ZCV1_DANRE | nrxn2a | 648 | ||
A0A8M9PTW7 | A0A8M9PTW7_DANRE | nrxn2a | 1667 | ||
A0A8M9PTX2 | A0A8M9PTX2_DANRE | nrxn2a | 1508 | ||
A0A8M2B8E6 | A0A8M2B8E6_DANRE | nrxn2a | 488 | ||
A0A8M3AU05 | A0A8M3AU05_DANRE | nrxn2a | 1652 | ||
A0A8M3AWZ3 | A0A8M3AWZ3_DANRE | nrxn2a | 1660 | ||
A0A8M9PCQ0 | A0A8M9PCQ0_DANRE | nrxn2a | 1645 | ||
A0A8M9PCQ2 | A0A8M9PCQ2_DANRE | nrxn2a | 1453 | ||
A0A8M9PIB2 | A0A8M9PIB2_DANRE | nrxn2a | 1668 | ||
A0A8M9PIB8 | A0A8M9PIB8_DANRE | nrxn2a | 458 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1594-1625 | Polar residues | ||||
Sequence: QVDQSRNSGSESNGAVVKEKTPSTTAAVAKTT |
Keywords
- Technical term