A0A8M9PHR9 · A0A8M9PHR9_DANRE
- ProteinFilamin C, gamma b (actin-binding protein 280)
- Geneflncb
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2773 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | intracellular non-membrane-bounded organelle | |
Molecular Function | actin filament binding | |
Biological Process | cilium assembly | |
Biological Process | heart development | |
Biological Process | locomotory behavior | |
Biological Process | muscle cell cellular homeostasis | |
Biological Process | nervous system development | |
Biological Process | sarcomere organization |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PHR9
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-18 | Polar residues | ||||
Sequence: MMSNNTYYDQQLPPQYYQ | ||||||
Region | 1-39 | Disordered | ||||
Sequence: MMSNNTYYDQQLPPQYYQGTDNGEDGDEEMPATEKDLAE | ||||||
Domain | 45-151 | Calponin-homology (CH) | ||||
Sequence: KIQQNTFTRWCNEHLKCLNRKILDLQKDLTDGLKLIGLLEVLSQKKMYRKYHARPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYS | ||||||
Domain | 168-271 | Calponin-homology (CH) | ||||
Sequence: LTPKQRLLGWIQNKVPQLHINNFHRDWRDGKALGALVDNCAPGLCPDWETWDPSQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKL | ||||||
Repeat | 279-377 | Filamin | ||||
Sequence: PKTLHPKRAKAYGPGIEPRGNVVLKPAEFVVETVEAGLGEVLVYIEDPEGHTEEARVIPNNDRNRSYSVVYVPKVEGLHKVKVLFAGQDIDRSPFLVNV | ||||||
Repeat | 379-477 | Filamin | ||||
Sequence: KALGDPNKVQARGPGLEPVGNVANKPTYFDIYTAGAGAGDVGVIIVDSQGRRDTVEIILENKGDSVFRCTYGPILEGPHTIYVTFAGQQIPRSPFTVHI | ||||||
Region | 484-532 | Disordered | ||||
Sequence: GRQIGSPVHIIPQSLRTPPSEKAKKVPPPTPPKPRRPTSNPNACRAIGR | ||||||
Compositional bias | 505-521 | Pro residues | ||||
Sequence: KAKKVPPPTPPKPRRPT | ||||||
Repeat | 519-615 | Filamin | ||||
Sequence: RPTSNPNACRAIGRGLQPKGVRVKEVADFKVYTKGAGSGELRVHVKGPTGGDEPVKVEDLGDGVYECDYYPIFCGKYIITVTWGGHAIPRSPFEVII | ||||||
Repeat | 616-708 | Filamin | ||||
Sequence: SEDAGPQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVLYWPTEPGDYAVHVICDDEDIKDSPFMAHI | ||||||
Repeat | 712-808 | Filamin | ||||
Sequence: ASDVFPEKVKCYGPGLEPTGCIVNKPAEFTIDARGAGRGQLQIYAQDSEGFPINIQITDNGDSTYFCVYIPIKPIKHTIIITWGEVNVPNSPFRVTI | ||||||
Repeat | 809-911 | Filamin | ||||
Sequence: GEGSHPENVKVHGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFADQEIPISPFRIKV | ||||||
Repeat | 912-1010 | Filamin | ||||
Sequence: DPSHDANKVKAEGPGLNKTGVEVGKPTHFTIYTKGAGKATPEVHFTASGRGDAVSDFEIIDNHDYSFTVRYTALQQGNMTISVCHGGDPIPKSPFTISV | ||||||
Repeat | 1011-1106 | Filamin | ||||
Sequence: APPLDLNKVKVHGLNNKVDVGKDEEFTVNTRGAGGQGKVDVKITSPSRRPIPCKVESGASNEVHTVKYIPPEEGPYKVDISYDGNPVPGSPFTVEG | ||||||
Repeat | 1107-1199 | Filamin | ||||
Sequence: VMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYSINILFADAHIPGSPFKAMV | ||||||
Repeat | 1200-1294 | Filamin | ||||
Sequence: QSVFDPSKVTASGPGLERGKVNEAGSFTVDCSKAGEAELTIEIISDSGAQAEVHVQNNSDGTYSITYIPPFHGMYTITIKYGGHAVPKFPARVQV | ||||||
Repeat | 1295-1394 | Filamin | ||||
Sequence: DPALDTSGIKVYGPGVEPRGVLREVTTHFIVDTRVHNKMGGNHIKVRIVNPSGANTDAYVTDKADGTYRVEYTAYEDGVHLIEVLYDDVPVPKSPFRVAV | ||||||
Repeat | 1395-1487 | Filamin | ||||
Sequence: AEGCDPSRVRAYGPGLEEGLVNKPNRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGEYDVNITFGGLPIPGSPFRVPV | ||||||
Repeat | 1488-1583 | Filamin | ||||
Sequence: RELVDPSKVKCTGPGLGSGVRAHVPQTFTVDCSKAGLAPLEVLLYGPTGMTEPVNITDNGDGTHTVVYTPAKDGPYTVCVKYADQEVPRSPFKIKV | ||||||
Repeat | 1584-1680 | Filamin | ||||
Sequence: LPAHDASKVRASGPGLNASGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNRDGTYTVSYVPDMTGRYTITIKYGGDEIPYSPYRIHA | ||||||
Repeat | 1693-1784 | Filamin | ||||
Sequence: VSIGGHGLGSGLGPTIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENADGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVA | ||||||
Repeat | 1833-1902 | Filamin | ||||
Sequence: FNLVIPFTVQKGEITGEVHMPSGKTASPHITDNKDGTVTVKYAPTEKGLHEMDIKYDGNHIPGSPLQFYV | ||||||
Repeat | 1902-1994 | Filamin | ||||
Sequence: VDAINSGHVNAYGPGLSHGMVNKSATFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIAGSPFTAKI | ||||||
Repeat | 1992-2081 | Filamin | ||||
Sequence: AKITGDDSMRTSQLNVGTATDVSLKITETDLSSLSATIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVKKNGKHVTNSPFKIMV | ||||||
Repeat | 2084-2176 | Filamin | ||||
Sequence: SEIGDASKVKVSGKGLIEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCSDVDDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKV | ||||||
Region | 2230-2315 | Disordered | ||||
Sequence: SHTYTRTERTEISKTRAGETKREVRVEESTQVGGDPFRDVFGGFMGRESLGPFNSPQGRQSEGESGTQEMTAQVTSPSGNTEDAEI | ||||||
Compositional bias | 2231-2258 | Basic and acidic residues | ||||
Sequence: HTYTRTERTEISKTRAGETKREVRVEES | ||||||
Repeat | 2251-2355 | Filamin | ||||
Sequence: REVRVEESTQVGGDPFRDVFGGFMGRESLGPFNSPQGRQSEGESGTQEMTAQVTSPSGNTEDAEIIEGEDSTYSVRFVPHEMGPHTVNVKYRGQHVPGSPFQFTV | ||||||
Compositional bias | 2282-2311 | Polar residues | ||||
Sequence: FNSPQGRQSEGESGTQEMTAQVTSPSGNTE | ||||||
Repeat | 2358-2450 | Filamin | ||||
Sequence: LGEGGAHKVRAGGTGLDRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVAYIVQEPGDYEVSIKFNDEHIPDSPFIVPI | ||||||
Repeat | 2452-2545 | Filamin | ||||
Sequence: SLSDDARLLTVTSLQEMGLKVNQEASFAVQLNGARGAIDAKVHTPSGAVEECYITELDNDKHAIRFIPRENGVHSIDVRFNGSHIPGSPFKIRV | ||||||
Repeat | 2549-2641 | Filamin | ||||
Sequence: GQAGDPGMVTAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKV | ||||||
Repeat | 2678-2772 | Filamin | ||||
Sequence: KFSSDASKVVSRGAGLSKAFIGQKNTFTVDCSKAGTNMLMVGVHGPKTPCEEVYVKHMGNRMYNVTYTVKEKGDYILIVKWGEEMVPGSPFHVTV |
Sequence similarities
Belongs to the filamin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,773
- Mass (Da)297,889
- Last updated2022-08-03 v1
- Checksum32865ABF7CEA3D46
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9Q104 | A0A8M9Q104_DANRE | flncb | 2742 | ||
A0A8M9Q107 | A0A8M9Q107_DANRE | flncb | 2660 | ||
A0A8M9Q6A0 | A0A8M9Q6A0_DANRE | flncb | 2649 | ||
A0A8M9PV09 | A0A8M9PV09_DANRE | flncb | 2772 | ||
A0A8M9PV14 | A0A8M9PV14_DANRE | flncb | 2691 | ||
A0A8M9Q696 | A0A8M9Q696_DANRE | flncb | 2731 | ||
A0A8M9QBS4 | A0A8M9QBS4_DANRE | flncb | 2732 | ||
A0A8M9QBT0 | A0A8M9QBT0_DANRE | flncb | 2619 | ||
A0A8M9PHS4 | A0A8M9PHS4_DANRE | flncb | 2701 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-18 | Polar residues | ||||
Sequence: MMSNNTYYDQQLPPQYYQ | ||||||
Compositional bias | 505-521 | Pro residues | ||||
Sequence: KAKKVPPPTPPKPRRPT | ||||||
Compositional bias | 2231-2258 | Basic and acidic residues | ||||
Sequence: HTYTRTERTEISKTRAGETKREVRVEES | ||||||
Compositional bias | 2282-2311 | Polar residues | ||||
Sequence: FNSPQGRQSEGESGTQEMTAQVTSPSGNTE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX470230 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |