A0A8M9PH62 · A0A8M9PH62_DANRE
- ProteinCytosolic purine 5'-nucleotidase
- Genent5c2b
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids564 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Catalytic activity
- AMP + inosine = adenosine + IMP
- CMP + inosine = cytidine + IMP
- GMP + H2O = guanosine + phosphateThis reaction proceeds in the forward direction.
- GMP + inosine = guanosine + IMP
- H2O + XMP = phosphate + xanthosineThis reaction proceeds in the forward direction.
- dGMP + H2O = 2'-deoxyguanosine + phosphateThis reaction proceeds in the forward direction.
- dGMP + inosine = 2'-deoxyguanosine + IMP
- dIMP + H2O = 2'-deoxyinosine + phosphateThis reaction proceeds in the forward direction.
- dIMP + inosine = 2'-deoxyinosine + IMP
- inosine + UMP = IMP + uridine
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 5'-nucleotidase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | transferase activity | |
Biological Process | GMP metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytosolic purine 5'-nucleotidase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PH62
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 538-564 | Disordered | ||||
Sequence: LFAQPPQEITHCHDEDDDEEEEEEEEE | ||||||
Compositional bias | 550-564 | Acidic residues | ||||
Sequence: HDEDDDEEEEEEEEE |
Sequence similarities
Belongs to the 5'(3')-deoxyribonucleotidase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length564
- Mass (Da)65,249
- Last updated2022-08-03 v1
- ChecksumFDAB07B6C3645D6A
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9PUC7 | A0A8M9PUC7_DANRE | nt5c2b | 370 | ||
F1QAK5 | F1QAK5_DANRE | nt5c2b | 562 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 550-564 | Acidic residues | ||||
Sequence: HDEDDDEEEEEEEEE |
Keywords
- Technical term