A0A8M9PCW2 · A0A8M9PCW2_DANRE

Function

Catalytic activity

Features

Showing features for binding site.

111401002003004005006007008009001,0001,100
TypeIDPosition(s)Description
Binding site508ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell projection
Cellular Componentcytoskeleton
Cellular Componentfocal adhesion
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionprotein tyrosine kinase activity
Biological Processlens fiber cell morphogenesis
Biological Processmidbrain-hindbrain boundary morphogenesis
Biological Processpositive regulation of cell population proliferation
Biological Processregulation of cellular component organization
Biological Processregulation of protein localization
Biological Processsignal complex assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific protein-tyrosine kinase
  • EC number

Gene names

    • Name
      ptk2ab
    • Synonyms
      fak
      , fak1a
      , ptk2
      , ptk2.1
      , ptk2a
      , wu:fa18c04
      , zgc:66114

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M9PCW2

Proteomes

Organism-specific databases

Subcellular Location

Cell junction, focal adhesion
Cell membrane
; Peripheral membrane protein
Membrane
; Peripheral membrane protein

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain71-388FERM
Domain476-734Protein kinase
Region738-780Disordered
Region799-828Disordered
Compositional bias917-931Basic and acidic residues
Region917-985Disordered

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,140
  • Mass (Da)
    129,078
  • Last updated
    2022-08-03 v1
  • Checksum
    AA7728C3A1D50380
MFLEGCLSPELRFALACTCWPFFRKEYDGQLAPTKAMAAAYLDPNPTHALNQGVKPRFSSGMERTAAALERVLKIFHYFESSSEPCSWASNIRHGDSTDVRGIIQKILDIHKVRCVSCFGLRLSHLRTGEIHWLHPDMGVSHVRERYEHSHPQDDWRYELRIRYLPKGFLNQFTEDQPTLNYFYHQVKSDYMMEIADQVDQDIALKLGCLEIRRFFRDMPGNALDKKSNYELLEKDVGLRRFFPKSLLDSVKAKSLRKLIQQTFKQFANLNNEQCMLKFFEILSPIYRFDKECFKCALGSSWVISVELAIGPEEGISYLTDKGSNPTHLANFTQVQTIQFEERERKGMLLLDVAGAPEPLTVTTTTLNTAENMADLIDGYCRLVSGTSSSFIVRVQKEGERALPSIPKAPKSANHEKRLQGVRAKAISISDDIGGDETDDYAEIIDEEDTYTMPSSTTEYYGLDEARDYEIQRDRIELGRCIGEGQFGDVHQGIYICPDTPALSVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQIRKYNLDLASLILFSYQLSTALAYLESKRFVHRDIAARNVLVSSVDCVKLGDFGLSRYMEDSSYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIENGERLAMPPNCPPTLYSLMTKCWAYDPSKRPRFTELKGQLSTILAEEKAQQEERSRMEMRRQVPVSWDSGGSDEAPPKGPRTRPSVPPGIFFDPYYPSMQQLSLSHAPYRFTQPSRPGYPSPRSSEGFYPSPQHMGQHNHYQMAGHSGPHGLLSVPGGLYPPQATVTGLDPHDSWNHRRVAQDHMWNPSMEDGVALRGGLSQLMEEQLILQQQQMEDDQRWLEHEERLLKPDGRSSRGSTERDDGSLQGPTGNQHIYQPIGKAEHAAPPKKPPRPGAPSHAAGVSGLNPTESYNEGVKPWRIQPQEINPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPAHTHREIEMAQKLLNSDLAELINKMKLAQQYVMTSLQQDYKKQMLTAAHALAVDAKNLLDVIDQARLKLLGQARPH

Computationally mapped potential isoform sequences

There are 17 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9P7Q1A0A8M9P7Q1_DANREptk2ab1142
A0A8M9PM54A0A8M9PM54_DANREptk2ab1139
A0A8M9PM62A0A8M9PM62_DANREptk2ab1132
A0A8M9PJ68A0A8M9PJ68_DANREptk2ab1139
A0A8M9PJ73A0A8M9PJ73_DANREptk2ab1126
A0A2R8RR02A0A2R8RR02_DANREptk2ab1101
A0A8M2B4H7A0A8M2B4H7_DANREptk2ab1104
A0A8M2B4I9A0A8M2B4I9_DANREptk2ab1088
A0A8M9P7Q4A0A8M9P7Q4_DANREptk2ab1136
A0A8M9P7Q9A0A8M9P7Q9_DANREptk2ab1104
A0A8M2B500A0A8M2B500_DANREptk2ab1091
A0A8M2B527A0A8M2B527_DANREptk2ab1097
A0A8M9NZ24A0A8M9NZ24_DANREptk2ab1107
A0A8M9NZ18A0A8M9NZ18_DANREptk2ab1136
A0A8M9PCW5A0A8M9PCW5_DANREptk2ab1133
A0A8M9PCX0A0A8M9PCX0_DANREptk2ab1104
Q98SN4Q98SN4_DANREptk2ab1050

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias917-931Basic and acidic residues

Keywords

Sequence databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp