A0A8M9PBF7 · A0A8M9PBF7_DANRE
- ProteinWASH complex subunit 2 isoform X2
- Genewashc2c
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1380 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | early endosome | |
Cellular Component | early endosome membrane | |
Cellular Component | plasma membrane | |
Cellular Component | WASH complex | |
Molecular Function | phosphatidylinositol phosphate binding | |
Molecular Function | retromer complex binding | |
Biological Process | protein localization to endosome | |
Biological Process | retrograde transport, endosome to Golgi |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M9PBF7
Proteomes
Organism-specific databases
Subcellular Location
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 103-129 | Disordered | ||||
Sequence: EEVEDPTPKSETTERQPEQEKTREQKE | ||||||
Region | 202-1002 | Disordered | ||||
Sequence: VGLGDLSSDEMSIGSDRDSVLESDVEDGDEHTDQDDYSDQDEEVQGNFKKKPSIASYNDADEENDDSDIFGGSDKDEDEDDLRKDTGVPSFADELAARIKGETQNKPEADRSSLSSGPSTTSKKSKTKKVPKPQVEDDQDEMFRPPTMEDEEYSPFGGKGGLFSGGKGLFDDDDEGDLFSEAPKNVPVEKEKTVAQPTEPHKTKKIPTGAVSIFPGNSLLGSANDSESPKSSDSRSPALPKASIGGGLFDDDEDDDDFFSGKTQSKSTPGQDKKTPKKTVDLFGEADEEDEDEDDDTAMFSGKAISALPQQDISANGEEETRPPEKKPPAGAVSMFGPGTKNILEGLKKRRPSTSEESTKSEESGHAPEPVKSSPALGSAEKMQSKSLFSDDEDSQIFSSENTSKSKPTTQNKPSKAPLSIFDDEEEEDLFSSTPKPVPVKKTSLPPKNALSSSLFSDDEDQWMSSKSSKENPEVKPSGMKPSISAPSRLPSVKTTHKDGLFDDKDDEDLFAATNQSSKTSSQRVSLLFEDEDDEDKEPLFGFKTPAIKTPPESKTSGVSSLFESTEEDTGPSVVKEKITEEKKKPVESVPSSEDSFEVKKKPAGAVSLFGGIDILGDKQDTIKKPPKTQEEIPDDELQKEGPPPMESKGTKTKKTALSLFDEDDDDDDDDFSTDEIIPAPTASRSTEKNALKEHGPRMKSTGVFQDEELLFSQTQQRDNDPDVDLFATSPKPAVPPQSSAKSVAPTLFGDDDDDDLFSSAKPKAPPKVPEKPSKPKTNEIDKSISTSSKEPTNPLKSKKT | ||||||
Compositional bias | 223-242 | Acidic residues | ||||
Sequence: ESDVEDGDEHTDQDDYSDQD | ||||||
Compositional bias | 260-276 | Acidic residues | ||||
Sequence: DADEENDDSDIFGGSDK | ||||||
Compositional bias | 309-325 | Polar residues | ||||
Sequence: EADRSSLSSGPSTTSKK | ||||||
Compositional bias | 330-349 | Basic and acidic residues | ||||
Sequence: KVPKPQVEDDQDEMFRPPTM | ||||||
Compositional bias | 385-400 | Basic and acidic residues | ||||
Sequence: KNVPVEKEKTVAQPTE | ||||||
Compositional bias | 416-439 | Polar residues | ||||
Sequence: PGNSLLGSANDSESPKSSDSRSPA | ||||||
Compositional bias | 545-568 | Basic and acidic residues | ||||
Sequence: LEGLKKRRPSTSEESTKSEESGHA | ||||||
Compositional bias | 579-618 | Polar residues | ||||
Sequence: GSAEKMQSKSLFSDDEDSQIFSSENTSKSKPTTQNKPSKA | ||||||
Compositional bias | 647-674 | Polar residues | ||||
Sequence: PPKNALSSSLFSDDEDQWMSSKSSKENP | ||||||
Compositional bias | 697-713 | Basic and acidic residues | ||||
Sequence: THKDGLFDDKDDEDLFA | ||||||
Compositional bias | 751-769 | Polar residues | ||||
Sequence: TPPESKTSGVSSLFESTEE | ||||||
Compositional bias | 771-802 | Basic and acidic residues | ||||
Sequence: TGPSVVKEKITEEKKKPVESVPSSEDSFEVKK | ||||||
Compositional bias | 819-844 | Basic and acidic residues | ||||
Sequence: DKQDTIKKPPKTQEEIPDDELQKEGP | ||||||
Compositional bias | 889-903 | Basic and acidic residues | ||||
Sequence: EKNALKEHGPRMKST | ||||||
Compositional bias | 908-924 | Polar residues | ||||
Sequence: DEELLFSQTQQRDNDPD | ||||||
Compositional bias | 981-1002 | Polar residues | ||||
Sequence: EIDKSISTSSKEPTNPLKSKKT | ||||||
Domain | 995-1115 | FAM21/CAPZIP | ||||
Sequence: NPLKSKKTSRIGELQAVLALNPAGLLPGAVPRAPGAVSVIPGLAHTGLPAAARTMPDHQGSSEGGVSFDSPALISTLLNANKGRAKGAGKRRPQTRAARHLAAQQSDEASGENVSVQKNEP | ||||||
Region | 1074-1293 | Disordered | ||||
Sequence: ANKGRAKGAGKRRPQTRAARHLAAQQSDEASGENVSVQKNEPAMAASLPPFNPVSVRPSALTIPVSAPAPAKSPDEAVRPKRFLEPTDDLFDSDDLFATKPVSSSKHKIQTTEEGQKKVSNTEDVTPSKKDQAPSIFDSHDEDLFATVKPKSVQKAKHMPFLDEGGEDSDEDIFGAGKSKSLESKNSKKEASAVKSDIFQDEVKEPPKAQKNPKEASLDA | ||||||
Compositional bias | 1100-1114 | Polar residues | ||||
Sequence: SDEASGENVSVQKNE | ||||||
Compositional bias | 1148-1168 | Basic and acidic residues | ||||
Sequence: DEAVRPKRFLEPTDDLFDSDD | ||||||
Compositional bias | 1183-1198 | Basic and acidic residues | ||||
Sequence: QTTEEGQKKVSNTEDV | ||||||
Compositional bias | 1207-1221 | Basic and acidic residues | ||||
Sequence: PSIFDSHDEDLFATV | ||||||
Compositional bias | 1244-1285 | Basic and acidic residues | ||||
Sequence: EDIFGAGKSKSLESKNSKKEASAVKSDIFQDEVKEPPKAQKN | ||||||
Region | 1330-1380 | Disordered | ||||
Sequence: DMDDIFSTGTTKPTVKPSSKSKKSQPIQEPASTAETAHNIFDDPLNAFGGN | ||||||
Compositional bias | 1336-1364 | Polar residues | ||||
Sequence: STGTTKPTVKPSSKSKKSQPIQEPASTAE |
Sequence similarities
Belongs to the FAM21 family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,380
- Mass (Da)150,000
- Last updated2022-08-03 v1
- ChecksumA6B6E96868A15810
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M2B2V0 | A0A8M2B2V0_DANRE | washc2c | 1381 | ||
A0A8M6Z9C4 | A0A8M6Z9C4_DANRE | washc2c | 1363 | ||
A0A8M9PMY0 | A0A8M9PMY0_DANRE | washc2c | 1363 | ||
A0A8M1RJ04 | A0A8M1RJ04_DANRE | washc2c | 1380 | ||
A0A8M2B314 | A0A8M2B314_DANRE | washc2c | 1363 | ||
A0A8M9PU38 | A0A8M9PU38_DANRE | washc2c | 1381 | ||
A0A8M9PU42 | A0A8M9PU42_DANRE | washc2c | 1359 | ||
A0A8M9Q511 | A0A8M9Q511_DANRE | washc2c | 1349 | ||
A0A8M9QA68 | A0A8M9QA68_DANRE | washc2c | 1359 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 223-242 | Acidic residues | ||||
Sequence: ESDVEDGDEHTDQDDYSDQD | ||||||
Compositional bias | 260-276 | Acidic residues | ||||
Sequence: DADEENDDSDIFGGSDK | ||||||
Compositional bias | 309-325 | Polar residues | ||||
Sequence: EADRSSLSSGPSTTSKK | ||||||
Compositional bias | 330-349 | Basic and acidic residues | ||||
Sequence: KVPKPQVEDDQDEMFRPPTM | ||||||
Compositional bias | 385-400 | Basic and acidic residues | ||||
Sequence: KNVPVEKEKTVAQPTE | ||||||
Compositional bias | 416-439 | Polar residues | ||||
Sequence: PGNSLLGSANDSESPKSSDSRSPA | ||||||
Compositional bias | 545-568 | Basic and acidic residues | ||||
Sequence: LEGLKKRRPSTSEESTKSEESGHA | ||||||
Compositional bias | 579-618 | Polar residues | ||||
Sequence: GSAEKMQSKSLFSDDEDSQIFSSENTSKSKPTTQNKPSKA | ||||||
Compositional bias | 647-674 | Polar residues | ||||
Sequence: PPKNALSSSLFSDDEDQWMSSKSSKENP | ||||||
Compositional bias | 697-713 | Basic and acidic residues | ||||
Sequence: THKDGLFDDKDDEDLFA | ||||||
Compositional bias | 751-769 | Polar residues | ||||
Sequence: TPPESKTSGVSSLFESTEE | ||||||
Compositional bias | 771-802 | Basic and acidic residues | ||||
Sequence: TGPSVVKEKITEEKKKPVESVPSSEDSFEVKK | ||||||
Compositional bias | 819-844 | Basic and acidic residues | ||||
Sequence: DKQDTIKKPPKTQEEIPDDELQKEGP | ||||||
Compositional bias | 889-903 | Basic and acidic residues | ||||
Sequence: EKNALKEHGPRMKST | ||||||
Compositional bias | 908-924 | Polar residues | ||||
Sequence: DEELLFSQTQQRDNDPD | ||||||
Compositional bias | 981-1002 | Polar residues | ||||
Sequence: EIDKSISTSSKEPTNPLKSKKT | ||||||
Compositional bias | 1100-1114 | Polar residues | ||||
Sequence: SDEASGENVSVQKNE | ||||||
Compositional bias | 1148-1168 | Basic and acidic residues | ||||
Sequence: DEAVRPKRFLEPTDDLFDSDD | ||||||
Compositional bias | 1183-1198 | Basic and acidic residues | ||||
Sequence: QTTEEGQKKVSNTEDV | ||||||
Compositional bias | 1207-1221 | Basic and acidic residues | ||||
Sequence: PSIFDSHDEDLFATV | ||||||
Compositional bias | 1244-1285 | Basic and acidic residues | ||||
Sequence: EDIFGAGKSKSLESKNSKKEASAVKSDIFQDEVKEPPKAQKN | ||||||
Compositional bias | 1336-1364 | Polar residues | ||||
Sequence: STGTTKPTVKPSSKSKKSQPIQEPASTAE |
Keywords
- Technical term