A0A8M6Z1D0 · A0A8M6Z1D0_DANRE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

111161002003004005006007008009001,0001,100
Type
IDPosition(s)Description
Binding site252Ca2+ 1 (UniProtKB | ChEBI)
Binding site252Ca2+ 2 (UniProtKB | ChEBI)
Binding site350Ca2+ 1 (UniProtKB | ChEBI)
Binding site402Zn2+ (UniProtKB | ChEBI); catalytic
Active site403
Binding site406Zn2+ (UniProtKB | ChEBI); catalytic
Binding site412Zn2+ (UniProtKB | ChEBI); catalytic
Binding site462Ca2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextracellular matrix
Cellular Componentextracellular region
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processextracellular matrix organization
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1
    • ADAM metallopeptidase with thrombospondin type 1 motif, 6

Gene names

    • Name
      adamts6

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M6Z1D0
  • Secondary accessions
    • E7FCQ4
    • E9QE55

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_504277479422-1116
Disulfide bond325↔386
Disulfide bond361↔368
Disulfide bond380↔462
Disulfide bond419↔446
Disulfide bond489↔511
Disulfide bond500↔518
Disulfide bond506↔541
Disulfide bond531↔546
Disulfide bond569↔606
Disulfide bond573↔611
Disulfide bond584↔596

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain249-467Peptidase M12B
Domain1078-1116PLAC

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,116
  • Mass (Da)
    124,651
  • Last updated
    2022-08-03 v1
  • Checksum
    8B77FE367957E91F
MEIFWKTLTWIFSLVLAAAEAQILSYNSQAEFLSTLEHYQLTVPVRVNEKGQFMSYTVKHYRPGRRRRGLDQTELDHTETRLFYKLSAYGKHFHLNLTLNPNLVSKHFTVEYWGKDGLDWQHSVVDNCHYVGYLLDQYSTTKVALSNCKGLHGVITTEDEQYLIEPLKNISRNFSDVNHEGQPHVIYKKTSIPSPQEPSKEFSCGVSDLTVNRTQFYNTNPKLNPDFPVLGVDSLMGAHRQRRSVSSERFVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDASLGNVVNIIVTRLIVLTEDQPNLEINHHADKSLDSFCKWQKSILSHQGDGNSIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDGIGNSCGTKGHETAKLMAAHITANTNPFSWSACSKDYITSFLDSGRGTCLDNEPLKRDFLYPTVAPGQVYDADEQCRFQYGASSRQCKYGEVCRELWCLSKSNRCVTNSIPAAEGTLCQTNTIEKGWCYQGECVAFGTWPQSVDGSWGPWTVWGECSRTCGGGVSSSMRHCDSPAPSGGGKYCLGERKRYRSCNTDACPEGSRDFREKQCADFDSLPFRGKYYNWKPYTGGGVKPCALNCLAEGYNFYTERSPAVIDGTRCQGDSLDICINGECKHVGCDNILGSDAKEDRCRVCGGDGSTCELTEGLFNDSLPRGGYMEVVQIPKGSVHIEIREVAVSKNYIALKSEGDDYYINGAWTIDWPRKFDIAGTAFHYKRPTDEPESLEALGATMENLVVMVLLQEQNLGIQYKFNVPIQRTGSGDNEVGFSWHHLPWSECSATCAGGSQKQEVVCKRLDDNSVVQNSYCDQDSKPPGNQRRCNTEPCPPEWFIGDWSECGKTCDGGIRTRTVLCIRKINPAEEETLEDSHCLTHRPIEQESCNNQSCPPQWVTLDWSECTPKCGPGFKHRIVLCKSSDLTKTFPAALCSDHSKPPVRIRCSLGRCPPPRWIPGEWGQCSAQCGLGQQMRTVQCLSYTGQPSSECLDSLRPNTMQQCESKCDSTPISGGDECKDVNKVAYCPLVLKFKFCSRAYFRQMCCKTCQGH

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9Q6C5A0A8M9Q6C5_DANREadamts6588
A0A8M3B350A0A8M3B350_DANREadamts6627
A0A8M9QGU5A0A8M9QGU5_DANREadamts6588
A0A8M9QKW4A0A8M9QKW4_DANREadamts6644

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR450775
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CR925713
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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