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A0A8M6YUX4 · A0A8M6YUX4_DANRE

Function

Catalytic activity

Features

Showing features for active site.

115052004006008001,0001,2001,400
TypeIDPosition(s)Description
Active site1115

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular Functionchromatin binding
Molecular FunctionDNA (cytosine-5-)-methyltransferase activity
Molecular FunctionDNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
Molecular FunctionDNA binding
Molecular Functionzinc ion binding
Biological ProcessB cell differentiation
Biological Processcartilage development
Biological Processdefinitive hemopoiesis
Biological Processdetermination of left/right symmetry
Biological Processdigestive tract development
Biological ProcessDNA methylation-dependent heterochromatin formation
Biological Processepigenetic regulation of gene expression
Biological Processexocrine pancreas development
Biological Processgranulocyte differentiation
Biological Processintrahepatic bile duct development
Biological ProcessKupffer's vesicle development
Biological Processlens development in camera-type eye
Biological Processliver development
Biological Processmethylation
Biological Processnegative regulation of gene expression via chromosomal CpG island methylation
Biological Processpancreas development
Biological Processretina layer formation
Biological Processretina morphogenesis in camera-type eye
Biological ProcessT cell differentiation in thymus

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA (cytosine-5)-methyltransferase
  • EC number

Gene names

    • Name
      dnmt1
    • Synonyms
      cb1075
      , cb983
      , ddn
      , dmnt1
      , fb05h01
      , mta
      , wu:fb05h01

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M6YUX4

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain5-102DMAP1-binding
Region86-232Disordered
Compositional bias134-148Basic and acidic residues
Compositional bias149-168Polar residues
Compositional bias170-216Basic and acidic residues
Domain530-576CXXC-type
Domain640-763BAH
Domain858-986BAH
Region981-1024Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,505
  • Mass (Da)
    169,758
  • Last updated
    2022-08-03 v1
  • MD5 Checksum
    B9CA8E4C37A3884FAB35E64B9FEFC3BD
MPTKTSLSLPEDVKERLQVLDEGGDSLSDEECVKEKLRLLQEFLLADTQDQLKNLEDKLKSSELSTEVYMSEVKAVLKKALGVVKEGDGVEQNGHSNGFSENGSHKDNGEQEGAMDTQEEGDAIKSPSAPKGRGGRRSKADSEPKKSPASSRVTRNTGKQQTIVSMFSRVPKRKSDELNGEPANGDTEIKTEETITEEVREEKRLKTEDEKPEAENAANLKPVSTAKTPPPKCPDCRQYLDDSDLKFFQGDPDDALDEPEMLTDERLSLFDSNEDGFESYEDLPQHKITNFSVYDKRGHLCPFDSGLIEKNVELYFSCAVKPIYDDNPCMDGGVPAKKLGPINAWWITGFDGGEKALIGFTTAFADYILMDPSEEYSAIFALMQEKIYMSKIVVEFLQKNQDATYEDLLNKIETTVPPAGLNFNRFTEDTLLRHAQFVVEQVESYDEAGDSDEQPIIITPCMRDLIKLAGVTLGKSRQLYWRAARRQAVRHPTKIEKDNKGPTKATTTKLVYLIFDTFFSDQIDQNNKDGGVKRQRCGVCEVCQAPDCGKCSACKDMIKFGGSGRSKQACQKRRCPNLAVKEAEDDENMDEEDVLPVKDTKKMSQTKKKKQTKNKISWVGEPLKTEGKKEYYMKVRVENEVLEVGDCVSVSPDDPSHPLYLARITALWDDGEKMFHAHWFCRGTDTVLGESSDPLELFLVDECEDMQLSFIHGKVNVFYKAPSENWYMEGGMDEDIKVIDDDGESFFYQLHYEGECARFETPPKVTPSEDCKYKFCASCTRNKEREAESVPHAYEPLEDEESDSKVFYGLVNYKGEQYKVGDSVYLPPEAFNFVVKAASPVKRSHRKDDVDEDLYPEYYRKSSDYIKGSNLDAPQPFRIGRIKEIFCNKRSNGKPDTSEIKLRLYKFYRPENTHKGPKGAYHSDINQLYWSDEEATVSMTEVLTRCRVEYAEDLVESVQDYSNKGPDRFYFLEAYNAKTKSFEDPPNHARSAVNKGKGKGKGKGKGKGKAAPQEPQDQEPQEPVVPKLRTLDVFSGCGGLSEGFHQAGISETHWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKLVMSGEKTNSLGQKLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSYLSYCDYYRPKFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPRYPEPLHVFAPRACSLSVAVDEKKYVSNVTRGNGGIYRTITVRDTMSDLPEIRNGAAALEISYNGEPQSWFQRQIRGSQYQPILRDHICKDMSALVAARMRNIPLAPGSDWRDLPNFEVRLRDGTTTKKLRYTHPDKKNGRSGTGALRGVCSCSEGKPCDPADRQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRFFGNVLDKHRQVGNAVPPPLSKAIGLEVKKCVLEKMRENATEPVKQEKMELSD

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F1RCN0F1RCN0_DANREdnmt11500

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias134-148Basic and acidic residues
Compositional bias149-168Polar residues
Compositional bias170-216Basic and acidic residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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