A0A8M6YUR0 · A0A8M6YUR0_DANRE
- Proteinnon-specific serine/threonine protein kinase
- Generock2b
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1468 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 107 | ATP (UniProtKB | ChEBI) | |||
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M6YUR0
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 78-340 | Protein kinase | |||
Domain | 341-412 | AGC-kinase C-terminal | |||
Coiled coil | 431-608 | ||||
Coiled coil | 644-909 | ||||
Coiled coil | 942-1007 | ||||
Domain | 967-1035 | RhoBD | |||
Coiled coil | 1045-1090 | ||||
Region | 1173-1209 | Disordered | |||
Domain | 1209-1408 | PH | |||
Domain | 1319-1374 | Phorbol-ester/DAG-type | |||
Compositional bias | 1415-1445 | Polar residues | |||
Region | 1415-1468 | Disordered | |||
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,468
- Mass (Da)169,798
- Last updated2022-08-03 v1
- MD5 Checksum2F64A079CE195274BDF21021F2FB0387
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9PP53 | A0A8M9PP53_DANRE | rock2b | 1493 | ||
A0A8M6YWK7 | A0A8M6YWK7_DANRE | rock2b | 1426 | ||
A0A8M9PP57 | A0A8M9PP57_DANRE | rock2b | 1346 | ||
A0A8M9PSI1 | A0A8M9PSI1_DANRE | rock2b | 1413 | ||
A0A8M1NDD8 | A0A8M1NDD8_DANRE | rock2b | 1401 | ||
A0A8M3AT74 | A0A8M3AT74_DANRE | rock2b | 941 | ||
A0A8M9PBK6 | A0A8M9PBK6_DANRE | rock2b | 1478 | ||
A0A8M9PH50 | A0A8M9PH50_DANRE | rock2b | 1471 | ||
A0A8M6Z372 | A0A8M6Z372_DANRE | rock2b | 1082 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1415-1445 | Polar residues | |||
Keywords
- Technical term