A0A8M3BCH5 · A0A8M3BCH5_DANRE
- Protein1-phosphatidylinositol-3-phosphate 5-kinase
- Genepikfyve
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2117 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasmic vesicle | |
Cellular Component | membrane | |
Cellular Component | perinuclear region of cytoplasm | |
Cellular Component | vesicle membrane | |
Molecular Function | 1-phosphatidylinositol-3-phosphate 5-kinase activity | |
Molecular Function | 1-phosphatidylinositol-5-kinase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Biological Process | intracellular signal transduction | |
Biological Process | lens fiber cell morphogenesis | |
Biological Process | lysosomal transport | |
Biological Process | melanosome organization | |
Biological Process | neutrophil chemotaxis | |
Biological Process | phagosome-lysosome fusion | |
Biological Process | phosphatidylinositol metabolic process | |
Biological Process | phosphorylation | |
Biological Process | regulation of reactive oxygen species biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name1-phosphatidylinositol-3-phosphate 5-kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M3BCH5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-19 | Polar residues | ||||
Sequence: MAADDKASSSSSVMDWSSE | ||||||
Region | 1-45 | Disordered | ||||
Sequence: MAADDKASSSSSVMDWSSEPPPSPTSPSHLTHFKPLTPEQDEPPL | ||||||
Region | 60-147 | Disordered | ||||
Sequence: KEKTGANIAPAKKLAKLEEGRPPSVTEKSQSASSSPQGPRRNWSSPSHSIHGSETHRKHPELLRRTSAASEGRRKSEAPLGSHDPRTA | ||||||
Compositional bias | 83-109 | Polar residues | ||||
Sequence: SVTEKSQSASSSPQGPRRNWSSPSHSI | ||||||
Compositional bias | 110-140 | Basic and acidic residues | ||||
Sequence: HGSETHRKHPELLRRTSAASEGRRKSEAPLG | ||||||
Domain | 177-237 | FYVE-type | ||||
Sequence: DSQCKECYDCNEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIAL | ||||||
Region | 320-369 | Disordered | ||||
Sequence: EDIGKSPARKRSASVTNLSLDRSGSSMVPAYESSVSPQNSRALPKTDHSE | ||||||
Compositional bias | 329-362 | Polar residues | ||||
Sequence: KRSASVTNLSLDRSGSSMVPAYESSVSPQNSRAL | ||||||
Domain | 391-466 | DEP | ||||
Sequence: NTTGMEFQDHRYWLRTYPNCIVGKELVNWLLRNGTISTRAQAIAIGQALVDGRWLDCVTHHDQIFRDEYALYRPLQ | ||||||
Compositional bias | 468-487 | Polar residues | ||||
Sequence: TEFSETPSPDSDSVNSLEGH | ||||||
Region | 468-495 | Disordered | ||||
Sequence: TEFSETPSPDSDSVNSLEGHSEPSWFKD | ||||||
Region | 509-528 | Disordered | ||||
Sequence: ENDYVTPSSSSPSKRTSVSS | ||||||
Compositional bias | 940-959 | Basic and acidic residues | ||||
Sequence: TTLREEDETSGERESQDNDE | ||||||
Region | 940-1035 | Disordered | ||||
Sequence: TTLREEDETSGERESQDNDESTLGDDNLTLVPGDDFETGFTGTIKAHSREPSTSESSHKDGESPRINKNASITSFSGGEEENIKTSTPLSSFSSTF | ||||||
Compositional bias | 990-1004 | Basic and acidic residues | ||||
Sequence: PSTSESSHKDGESPR | ||||||
Compositional bias | 1005-1035 | Polar residues | ||||
Sequence: INKNASITSFSGGEEENIKTSTPLSSFSSTF | ||||||
Region | 1241-1263 | Disordered | ||||
Sequence: RQREGTQFREAPPPKAPIKADSE | ||||||
Region | 1587-1677 | Disordered | ||||
Sequence: EKGRKRLSVPPSPGRHRQPTTDESKTSALESSPRNPSPVVPNGDKEDRHLNTFPSSSGSSSLLQLPSPAEQPSDVITSGPSFPDQDSVSNP | ||||||
Compositional bias | 1610-1624 | Polar residues | ||||
Sequence: SKTSALESSPRNPSP | ||||||
Compositional bias | 1638-1674 | Polar residues | ||||
Sequence: TFPSSSGSSSLLQLPSPAEQPSDVITSGPSFPDQDSV | ||||||
Compositional bias | 1767-1805 | Polar residues | ||||
Sequence: AKTGGDDTSQTISAGESRVKNSPAKPSDNSMSQLSRSSV | ||||||
Region | 1767-1827 | Disordered | ||||
Sequence: AKTGGDDTSQTISAGESRVKNSPAKPSDNSMSQLSRSSVDADPLKEPESADKQKKQTGNPH | ||||||
Domain | 1780-2103 | PIPK | ||||
Sequence: AGESRVKNSPAKPSDNSMSQLSRSSVDADPLKEPESADKQKKQTGNPHIELQFSDANAKFYCRIYYAEEFHKMREEIMESTEDDFVRSLSHCVNWQARGGKSGAVFYATEDDRFILKQMPRLEVQSFLDFAPHYFTYITGAVHLKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDQGKESCEVVLLDENLLKLVHDNPLYIRSHCKAILRAAIHSDALFLSSHLIIDYSLLVGRDDSTDELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYF | ||||||
Compositional bias | 1807-1824 | Basic and acidic residues | ||||
Sequence: ADPLKEPESADKQKKQTG |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,117
- Mass (Da)238,813
- Last updated2022-08-03 v1
- Checksum41BBB8231857B8CC
Computationally mapped potential isoform sequences
There are 10 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M3AW30 | A0A8M3AW30_DANRE | pikfyve | 2121 | ||
B2KTE1 | B2KTE1_DANRE | pikfyve | 2100 | ||
B2KTE2 | B2KTE2_DANRE | pikfyve | 2084 | ||
B2KTE3 | B2KTE3_DANRE | pikfyve | 2091 | ||
B2KTE4 | B2KTE4_DANRE | pikfyve | 2075 | ||
A0A8M3B5N9 | A0A8M3B5N9_DANRE | pikfyve | 2105 | ||
A0A8M3B2P6 | A0A8M3B2P6_DANRE | pikfyve | 2095 | ||
A0A8M3AW23 | A0A8M3AW23_DANRE | pikfyve | 2112 | ||
A0A8M3AW35 | A0A8M3AW35_DANRE | pikfyve | 1838 | ||
A0A8M2BF26 | A0A8M2BF26_DANRE | pikfyve | 2104 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-19 | Polar residues | ||||
Sequence: MAADDKASSSSSVMDWSSE | ||||||
Compositional bias | 83-109 | Polar residues | ||||
Sequence: SVTEKSQSASSSPQGPRRNWSSPSHSI | ||||||
Compositional bias | 110-140 | Basic and acidic residues | ||||
Sequence: HGSETHRKHPELLRRTSAASEGRRKSEAPLG | ||||||
Compositional bias | 329-362 | Polar residues | ||||
Sequence: KRSASVTNLSLDRSGSSMVPAYESSVSPQNSRAL | ||||||
Compositional bias | 468-487 | Polar residues | ||||
Sequence: TEFSETPSPDSDSVNSLEGH | ||||||
Compositional bias | 940-959 | Basic and acidic residues | ||||
Sequence: TTLREEDETSGERESQDNDE | ||||||
Compositional bias | 990-1004 | Basic and acidic residues | ||||
Sequence: PSTSESSHKDGESPR | ||||||
Compositional bias | 1005-1035 | Polar residues | ||||
Sequence: INKNASITSFSGGEEENIKTSTPLSSFSSTF | ||||||
Compositional bias | 1610-1624 | Polar residues | ||||
Sequence: SKTSALESSPRNPSP | ||||||
Compositional bias | 1638-1674 | Polar residues | ||||
Sequence: TFPSSSGSSSLLQLPSPAEQPSDVITSGPSFPDQDSV | ||||||
Compositional bias | 1767-1805 | Polar residues | ||||
Sequence: AKTGGDDTSQTISAGESRVKNSPAKPSDNSMSQLSRSSV | ||||||
Compositional bias | 1807-1824 | Basic and acidic residues | ||||
Sequence: ADPLKEPESADKQKKQTG |
Keywords
- Technical term