A0A8M3B0D1 · A0A8M3B0D1_DANRE
- ProteinTensin-1-like isoform X2
- Genetns1a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1687 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | focal adhesion | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoprotein phosphatase activity | |
Biological Process | fibroblast migration |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M3B0D1
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 41-88 | Phorbol-ester/DAG-type | ||||
Sequence: SHTFKAKSFKKAKSCAVCKQALTKEGLVCKVCKLSCHKKCEVKVATAC | ||||||
Compositional bias | 89-109 | Polar residues | ||||
Sequence: ESNPTTNPNQNQQASTKSPNM | ||||||
Region | 89-114 | Disordered | ||||
Sequence: ESNPTTNPNQNQQASTKSPNMDLKRR | ||||||
Domain | 122-294 | Phosphatase tensin-type | ||||
Sequence: MQTLEENNEVDLLYITERIIALSFPGGTEENKYSVHLREVTSMLRSKHQQHYLMLNLSERRHDITKQNPRVLDFGWPDHHAPALDKICSICKAMDTWLNADPHNVVVLHNKGNWGRTGVVVGAYMHYSNISASADQALDRFAMKRFYEDKAMPVGQPSQRRYVQYFAGLLSGH | ||||||
Domain | 299-425 | C2 tensin-type | ||||
Sequence: NKPLFLHHVIMHGIPNFESIGGCRPFLKIYQAMQPVYTSGIYNVKGDSHTSICITIEPGLLLKGDILLKCYHKRYQNPSRDVIFRVQFHTCALHNLALVFTKNDLDDTFKDERFPEYGKVEFIFSFD | ||||||
Compositional bias | 530-570 | Polar residues | ||||
Sequence: ALSVSSDSGNSTASVKTDRTDDAQQSLSSSGPVSQAPPGTV | ||||||
Region | 530-572 | Disordered | ||||
Sequence: ALSVSSDSGNSTASVKTDRTDDAQQSLSSSGPVSQAPPGTVIS | ||||||
Region | 621-663 | Disordered | ||||
Sequence: GAERETGIIDDELPESQVGDNSAGSLGTLSSFEGQDTPADSKT | ||||||
Compositional bias | 638-663 | Polar residues | ||||
Sequence: VGDNSAGSLGTLSSFEGQDTPADSKT | ||||||
Region | 798-825 | Disordered | ||||
Sequence: PSHTPVPKSQSAPPGENISAFHPPFGQT | ||||||
Compositional bias | 846-909 | Polar residues | ||||
Sequence: LSSSASFGQSSQRSSPAYPITPTSDHQRGYPQTPQTPQTPYSPIYQQDPYSIRGGSVTTPSPTL | ||||||
Region | 846-916 | Disordered | ||||
Sequence: LSSSASFGQSSQRSSPAYPITPTSDHQRGYPQTPQTPQTPYSPIYQQDPYSIRGGSVTTPSPTLTLPSPIK | ||||||
Compositional bias | 930-951 | Polar residues | ||||
Sequence: PDLQGTFPGPQKSYSASSSPLP | ||||||
Region | 930-960 | Disordered | ||||
Sequence: PDLQGTFPGPQKSYSASSSPLPPVTLAKEPE | ||||||
Region | 1001-1041 | Disordered | ||||
Sequence: SYSFSGSHSRTVTPDEAMPTVRRRTTSESQYLSSQHDSAAH | ||||||
Compositional bias | 1023-1040 | Polar residues | ||||
Sequence: RRTTSESQYLSSQHDSAA | ||||||
Region | 1111-1187 | Disordered | ||||
Sequence: PAEALVQQNSSDSDSSDEMEEPHGFVGTGIREGGFISPLHHPYSPASERPVPPAHTFSPPQPVNNTSSDGFGNQRAF | ||||||
Compositional bias | 1155-1169 | Pro residues | ||||
Sequence: PASERPVPPAHTFSP | ||||||
Compositional bias | 1170-1185 | Polar residues | ||||
Sequence: PQPVNNTSSDGFGNQR | ||||||
Region | 1227-1347 | Disordered | ||||
Sequence: NTLHRTVATNTPPSPALQRRLGGPSSPAFGRRITTANSGSEPTTPNSPLLGRSGKFIPPSPVLDRHPSPAPVASSPDHKVLPRGQATPDERHGAQSRQSITSTVQPGHATPTFPIEQSSSP | ||||||
Compositional bias | 1228-1242 | Polar residues | ||||
Sequence: TLHRTVATNTPPSPA | ||||||
Compositional bias | 1256-1276 | Polar residues | ||||
Sequence: GRRITTANSGSEPTTPNSPLL | ||||||
Compositional bias | 1317-1347 | Polar residues | ||||
Sequence: RHGAQSRQSITSTVQPGHATPTFPIEQSSSP | ||||||
Domain | 1407-1516 | SH2 | ||||
Sequence: WYKPEITREQAICILKDREPGAFVIRDSNSFRGAYGLAMKVASPPPTVQQNKKVGDITNELVRHFLIETSAKGVRLKGCPNEPYFGCLSALVYQHAITPLALPCKLMIPT |
Sequence similarities
Belongs to the PTEN phosphatase protein family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,687
- Mass (Da)184,511
- Last updated2022-08-03 v1
- Checksum4F27258CC07B6D4A
Computationally mapped potential isoform sequences
There are 12 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M3B3C3 | A0A8M3B3C3_DANRE | tns1a | 1688 | ||
A0A8N7UR56 | A0A8N7UR56_DANRE | tns1a | 1580 | ||
A0A8M6YYV2 | A0A8M6YYV2_DANRE | tns1a | 1686 | ||
A0A8M9PKB4 | A0A8M9PKB4_DANRE | tns1a | 529 | ||
A0A8M9Q1Z4 | A0A8M9Q1Z4_DANRE | tns1a | 422 | ||
A0A8M9PRC6 | A0A8M9PRC6_DANRE | tns1a | 528 | ||
A0A8M9PYL1 | A0A8M9PYL1_DANRE | tns1a | 530 | ||
A0A8M3ATA5 | A0A8M3ATA5_DANRE | tns1a | 1662 | ||
A0A8M3ATB1 | A0A8M3ATB1_DANRE | tns1a | 1687 | ||
A0A8M9P960 | A0A8M9P960_DANRE | tns1a | 529 | ||
A0A8M3B3C8 | A0A8M3B3C8_DANRE | tns1a | 1443 | ||
A0A8M3BAB4 | A0A8M3BAB4_DANRE | tns1a | 1679 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 89-109 | Polar residues | ||||
Sequence: ESNPTTNPNQNQQASTKSPNM | ||||||
Compositional bias | 530-570 | Polar residues | ||||
Sequence: ALSVSSDSGNSTASVKTDRTDDAQQSLSSSGPVSQAPPGTV | ||||||
Compositional bias | 638-663 | Polar residues | ||||
Sequence: VGDNSAGSLGTLSSFEGQDTPADSKT | ||||||
Compositional bias | 846-909 | Polar residues | ||||
Sequence: LSSSASFGQSSQRSSPAYPITPTSDHQRGYPQTPQTPQTPYSPIYQQDPYSIRGGSVTTPSPTL | ||||||
Compositional bias | 930-951 | Polar residues | ||||
Sequence: PDLQGTFPGPQKSYSASSSPLP | ||||||
Compositional bias | 1023-1040 | Polar residues | ||||
Sequence: RRTTSESQYLSSQHDSAA | ||||||
Compositional bias | 1155-1169 | Pro residues | ||||
Sequence: PASERPVPPAHTFSP | ||||||
Compositional bias | 1170-1185 | Polar residues | ||||
Sequence: PQPVNNTSSDGFGNQR | ||||||
Compositional bias | 1228-1242 | Polar residues | ||||
Sequence: TLHRTVATNTPPSPA | ||||||
Compositional bias | 1256-1276 | Polar residues | ||||
Sequence: GRRITTANSGSEPTTPNSPLL | ||||||
Compositional bias | 1317-1347 | Polar residues | ||||
Sequence: RHGAQSRQSITSTVQPGHATPTFPIEQSSSP |
Keywords
- Technical term