A0A8M3AZ17 · A0A8M3AZ17_DANRE

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Features

Showing features for active site, binding site.

159250100150200250300350400450500550
TypeIDPosition(s)Description
Active site328Nucleophile
Binding site328Mg2+ (UniProtKB | ChEBI)
Active site330Proton donor
Binding site330Mg2+ (UniProtKB | ChEBI)
Binding site556Mg2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular Functionmetal ion binding
Molecular Functionprotein tyrosine phosphatase activity
Biological Processadenohypophysis development
Biological Processcell differentiation
Biological Processear morphogenesis
Biological Processinner ear morphogenesis
Biological Processnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Biological Processotic vesicle morphogenesis
Biological Processotolith development
Biological Processpositive regulation of DNA repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Eyes absent homolog
  • EC number

Gene names

    • Name
      eya1
    • Synonyms
      wu:fc13c10
      , zgc:100770

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M3AZ17
  • Secondary accessions
    • E9QJ32

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-55Disordered
Compositional bias9-55Polar residues
Compositional bias67-88Polar residues
Region67-91Disordered
Compositional bias237-286Polar residues
Region237-321Disordered
Compositional bias287-307Basic and acidic residues

Sequence similarities

Belongs to the HAD-like hydrolase superfamily. EYA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    592
  • Mass (Da)
    64,759
  • Last updated
    2022-08-03 v1
  • Checksum
    7C329AABF4823141
MEMQDLASPHSRVSGSSESPNGPNIDNSHINNNSMTPNGTEVKTEPMSSSEIATSVADGSLDSFSGSAIGTSGFSPRQTHQFSPQIYPSNRPYPHILPTPSAQNMAAYGQTQYTTGMQQAAAYGTYPQPGQPYGISAYGPLWAGIKTEGGLTQAQSPGQSGFLSYSSSFSTPQTGQAPYSYQMQGGSFTTTSGLYAGSNSLTNSTGFNSTQQDYPSYPTFGQSQYAQYYNSSPYTSPYMTSNNTSPTTPSTTATYTLQEPPSGITSQALTEQPTGEYSTIHSPSTPIKDSDSDRLRRASDVKARGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRFGRDPPTSVSLGLRMEEMIFNLADTHFFFNDLEECDQVHIDDVSSDDNGQDLSTYNFSTDGFHAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSRSNCVNILVTTTQLIPALAKVLLYGLGVVFPIENIYSATKIGKESCFERVIQRFGRKVVYVVVGDGVEEEQGSKKHNMPFWRISSHSDLMALHHALDLEYL

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M6YVK2A0A8M6YVK2_DANREeya1614
Q9W6E8Q9W6E8_DANREeya1609
A0A8M3AP55A0A8M3AP55_DANREeya1613
A0A8M2B9H5A0A8M2B9H5_DANREeya1586
Q6DBY3Q6DBY3_DANREeya1587

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias9-55Polar residues
Compositional bias67-88Polar residues
Compositional bias237-286Polar residues
Compositional bias287-307Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX510326
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CR450806
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CT573498
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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