A0A8M3AV33 · A0A8M3AV33_DANRE

Function

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Features

Showing features for active site, binding site.

1886100200300400500600700800
Type
IDPosition(s)Description
Active site131Proton donor
Active site277
Active site371Proton donor
Active site389
Binding site475Ca2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum quality control compartment
Cellular Componentmembrane
Molecular Functioncalcium ion binding
Molecular Functionmannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Biological Processcarbohydrate metabolic process
Biological Processendoplasmic reticulum mannose trimming
Biological Processmannose trimming involved in glycoprotein ERAD pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    alpha-1,2-Mannosidase
  • EC number

Gene names

    • Name
      edem3

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M3AV33

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-28
ChainPRO_503544000029-886alpha-1,2-Mannosidase

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain665-756PA
Region788-886Disordered
Compositional bias813-834Polar residues

Sequence similarities

Belongs to the glycosyl hydrolase 47 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    886
  • Mass (Da)
    99,464
  • Last updated
    2022-08-03 v1
  • Checksum
    10E6C0D92229EF53
MWMLHSATMLPAFWLLFFMGTCIRLSETMSRDEKSKLRIQVLEMFDHAYRNYMDHAYPADELMPLTCRGRVRGLEPSRGDVDDALGKFSLTLIDTLDTLALLNKTVEFEEAVRRVVKDVRLDNDIVVSVFETNIRVLGGLLGGHSMAVMLKENGQMVWYQNELLHMAKDLGLRLLPAFNTSSGLPYPRVNLRHGVHGPETRTGTETETCTACAGTIILEFAALSRFTGDPTFEAHARRALDFLWEKRQRNSNLVGTTINIHSGEWVRRDSGVGAGIDSYYEYLMKAYILLGDDQLLLRFNTHYASIMKYISQPPLLLDVHIHKPLLPARTWMDSLLAFFPGLQVLKGDIRPAIETHEMLYQVTKKHNFLPEAFTTDFRVHWAQHPLRPEFAESTYFLYKATRDPYYLEVGRTVLENLNRFARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLFLLFAEEEDLPFNVEDYVFTTEAHLLPLSLSTASNSPAPPVINSVVIEELDDLNFEWTCPNTRLLFPDPAFPRNFREPIRSAVDKSCLRPIAHREPGMGRPPLRAQDFMANNPEHLELLRRMGVSLIHLKDGRVQLVQHATQAVSAVAAEDGMRFMQEMMELSSQQQKEQLPPRAVQIVSHPFFGRVVLTAGPAQFGMDLSKSSSGVRGFVTVAEPYNGCSELSNGEIVAGRIALLQRGQCMFAEKARHVQKAGAIGGIVIDDNEGSSSDTAPLFQMAGDGRNTDDVTLPLLFLFHKEGNILLEALKEYKEVEVLLSDKARDREAIFKGKALPGALLDGNGAEEEDCSTEERDHSSPAPSEPVDQSQVTTQEQTAGDSESVQPAEGLGSYVSVDAGEEPPADEDSNNQSVDSLMADWQEDLEAFKQMEKDEL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M2BEF7A0A8M2BEF7_DANREedem3888
A0A8N7T766A0A8N7T766_DANREedem3870
A0A8M2BE98A0A8M2BE98_DANREedem3872

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias813-834Polar residues

Keywords

Sequence databases

Similar Proteins

Disclaimer

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