A0A8M3AR84 · A0A8M3AR84_DANRE

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 3 Ca2+ ions per subunit. The ions are bound to the C2 domain.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site184Ca2+ 1 (UniProtKB | ChEBI)
Binding site185Ca2+ 1 (UniProtKB | ChEBI)
Binding site191Ca2+ 1 (UniProtKB | ChEBI)
Binding site193a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) (UniProtKB | ChEBI)
Binding site243a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) (UniProtKB | ChEBI)
Binding site244Ca2+ 1 (UniProtKB | ChEBI)
Binding site245Ca2+ 1 (UniProtKB | ChEBI)
Binding site246Ca2+ 2 (UniProtKB | ChEBI)
Binding site250Ca2+ 1 (UniProtKB | ChEBI)
Binding site252Ca2+ 3 (UniProtKB | ChEBI)
Binding site353-361ATP (UniProtKB | ChEBI)
Binding site376ATP (UniProtKB | ChEBI)
Active site471Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functiondiacylglycerol-dependent serine/threonine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionzinc ion binding
Biological Processintracellular signal transduction
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein kinase C
  • EC number

Gene names

    • Name
      prkcab
    • Synonyms
      si:ch73-374l24.1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M3AR84

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain34-84Phorbol-ester/DAG-type
Domain99-149Phorbol-ester/DAG-type
Domain156-273C2
Domain347-605Protein kinase
Domain606-676AGC-kinase C-terminal

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    681
  • Mass (Da)
    78,049
  • Last updated
    2022-08-03 v1
  • Checksum
    55467CDB5DBAD066
MADHLIQINDSSAGVNRFARKGALRQKNVHEVKNHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVSFSCPGADKGPDTDDPRSKHKFKIHSYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVMNVPSLCGTDHTERRGRIFMKIEVSGDRLHVTVGEARNLIPMDPNGLSDPYVKLKLIPDPKNETKQKTRTIRSSLNPTWNESFIFKLKASDKERRLSVEVWDWDRTTRNDFMGSMSFGVSELIKAPVSGWYKMLNQEEGEYYNVPIPEENDINLELRQKFEACQFNIHLLKKAKLGPGKKVITPTDHRRFSLPSGNMDKVRLNDFHFLALLGKGSFGKVMLAEMKSTEELYAIKILKKDVVIQDDDVECTMVEKRVLAQREKPPFLTQLHSCFQTVDRLYFVMEYINGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHRKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENMYEGMTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLTKEAVSICKGLMTKHPSKRLGCGAEGERDIKEQAFFRRIDWDRLANREIQPPFKPKVCGKAAENFDKFFTRTQPMLTPPDQLVIANIDQSEFAGFSFINPEFIHPASIHSVV

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M3B1B9A0A8M3B1B9_DANREprkcab671

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp