A0A8M3AQY6 · A0A8M3AQY6_DANRE
- Proteinnon-specific serine/threonine protein kinase
- Genedclk2a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids801 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | microtubule cytoskeleton | |
Cellular Component | nucleus | |
Cellular Component | synaptic vesicle | |
Molecular Function | ATP binding | |
Molecular Function | protein kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | hyperosmotic response | |
Biological Process | intracellular signal transduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M3AQY6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-22 | Basic and acidic residues | ||||
Sequence: MSSRNIEWEHFEEREKGHRSPR | ||||||
Region | 1-37 | Disordered | ||||
Sequence: MSSRNIEWEHFEEREKGHRSPRGSGGSHSGSRGNGIV | ||||||
Domain | 64-150 | Doublecortin | ||||
Sequence: KKVRFYRNGDKYFKGLVYAVSGDRFRSFDALLMELTRSLSDNVNLPQGVRSIYTADGGKKITSLDDLVEGESYVCASNEPFRKVDYT | ||||||
Domain | 191-274 | Doublecortin | ||||
Sequence: KLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGAVKRLYTLEGKQIICLQDFFGDDDVFIACGPEKYRYAQDD | ||||||
Region | 293-398 | Disordered | ||||
Sequence: SAPPVRYSGSKSPGTGRRSKSPGSARRTAGHFSTNSQSPVKSPINGAPNSQITTPKSAKSSSSSPTSPRSMRNFKIPTHHSSAGNVNGSSETPQHHNNSLSPEVNG | ||||||
Compositional bias | 304-398 | Polar residues | ||||
Sequence: SPGTGRRSKSPGSARRTAGHFSTNSQSPVKSPINGAPNSQITTPKSAKSSSSSPTSPRSMRNFKIPTHHSSAGNVNGSSETPQHHNNSLSPEVNG | ||||||
Domain | 411-668 | Protein kinase | ||||
Sequence: YKIGKVIGDGNFAVVKECVERSTGKEFALKIIDKNKCRGKEHLIENEVAVLRRVKHPNIIMLIEEVDTPAELYLVMELVKGGDLFDAITSSTKYTEKDASVMVFDLAAALKYLHRMCIVHRDIKPENLLVCEYPNGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAESGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILLGHLEFPSPFWDNISDSAKELIGHMLQVNVEARYTAEDVLSHPWV | ||||||
Region | 712-801 | Disordered | ||||
Sequence: DKETIQLSHRRQDRNPPRPEKRPSSTNPERRRSNRGRSSVQSEDSRSAAPIEPATSANPSAPAALPSDPSPQFHECNTESEASKDLLKEE | ||||||
Compositional bias | 715-750 | Basic and acidic residues | ||||
Sequence: TIQLSHRRQDRNPPRPEKRPSSTNPERRRSNRGRSS | ||||||
Compositional bias | 751-765 | Polar residues | ||||
Sequence: VQSEDSRSAAPIEPA |
Family and domain databases
Sequence
- Sequence statusComplete
- Length801
- Mass (Da)88,575
- Last updated2022-08-03 v1
- Checksum0521BC9ADA4B882B
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-22 | Basic and acidic residues | ||||
Sequence: MSSRNIEWEHFEEREKGHRSPR | ||||||
Compositional bias | 304-398 | Polar residues | ||||
Sequence: SPGTGRRSKSPGSARRTAGHFSTNSQSPVKSPINGAPNSQITTPKSAKSSSSSPTSPRSMRNFKIPTHHSSAGNVNGSSETPQHHNNSLSPEVNG | ||||||
Compositional bias | 715-750 | Basic and acidic residues | ||||
Sequence: TIQLSHRRQDRNPPRPEKRPSSTNPERRRSNRGRSS | ||||||
Compositional bias | 751-765 | Polar residues | ||||
Sequence: VQSEDSRSAAPIEPA |
Keywords
- Technical term