A0A8M2BKP3 · A0A8M2BKP3_DANRE
- ProteinStromal interaction molecule 1 isoform X1
- Genestim1a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids808 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | plasma membrane | |
Molecular Function | calcium channel regulator activity | |
Molecular Function | calcium ion binding | |
Biological Process | axon extension involved in axon guidance | |
Biological Process | intracellular calcium ion homeostasis | |
Biological Process | store-operated calcium entry |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M2BKP3
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 208-226 | Helical | ||||
Sequence: FMLVVSIVIGMGGCWFAYI |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MEFSGLVTFWIACICFLLQCRA | ||||||
Chain | PRO_5035426862 | 23-808 | ||||
Sequence: DKLNPVNTDPLPADNGVSELCRIDEPLCQDENAILSFEAIRSIHKQMDDDDNGNVDVLETDGFLREDLNYHDPKGKHNTFHGDDQFISVEDLWNAWKSSEVYNWTVDEVVKWLIDYVELTQYVEAIKKLNFSGTAMPRLAVKNNTLTQTVLKILDRSHVQKLQLKALDTVLFGAPMMNRHNHLKDFMLVVSIVIGMGGCWFAYIQNRHSKDHMKKMMKDLDSLQRAEQSLHDLQQKLQIAQEEHRSVEVEKVNLEQKLRDEINTAKQEAQRLKELREGTENELSRQKYAEEELEQVRMALKKAEKELESRSSWSPPEALQKWLQLTHEVEVQYYNIKKQNAERQLQVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILAAKQALGEVTAALRERLHRWQQIELLTGFTLVHNPGLPSLASALNLDPSFMGGRGTPQHFMSDDMDDMDEDIVPPGTLQYAAWLMGRRASDLWSLNSDCQSFWKNSAPSMMSLRQRHIDPQMALGSQRLVESCLALGGQEGEGSLYSSRPRTAMRQARSQSFGQFEALGLPPLSSAMSHPAIYSASSSHIPHSSSVAPHASHYHSSHFQPMDTIPDLPYDASPERPRHCGSHGDLNRSDSDSSLCISQTGEQLRLSYSSKGFPVKPTSLLHGPHSRSEEGAQSHTHNGGNRVHDGGPSPDGVPDSPILMKKLYGIEKSASMSEIHGSQAAMSMSESSRSLSPNSTEPDTPSPTGLTGGKAGNRIPQISSKKSPLEEDSGSTGEDTDSAASRKKHTFKIFKKQKK |
Structure
Family & Domains
Features
Showing features for coiled coil, domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 238-332 | |||||
Sequence: MMKDLDSLQRAEQSLHDLQQKLQIAQEEHRSVEVEKVNLEQKLRDEINTAKQEAQRLKELREGTENELSRQKYAEEELEQVRMALKKAEKELESR | ||||||
Domain | 335-435 | Stromal interaction molecule Orai1-activating region | ||||
Sequence: WSPPEALQKWLQLTHEVEVQYYNIKKQNAERQLQVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILAAKQALGEVTAALRERLHRWQQIELLTGFTL | ||||||
Compositional bias | 589-612 | Polar residues | ||||
Sequence: ASSSHIPHSSSVAPHASHYHSSHF | ||||||
Region | 589-648 | Disordered | ||||
Sequence: ASSSHIPHSSSVAPHASHYHSSHFQPMDTIPDLPYDASPERPRHCGSHGDLNRSDSDSSL | ||||||
Compositional bias | 625-639 | Basic and acidic residues | ||||
Sequence: ASPERPRHCGSHGDL | ||||||
Region | 661-711 | Disordered | ||||
Sequence: YSSKGFPVKPTSLLHGPHSRSEEGAQSHTHNGGNRVHDGGPSPDGVPDSPI | ||||||
Compositional bias | 727-779 | Polar residues | ||||
Sequence: EIHGSQAAMSMSESSRSLSPNSTEPDTPSPTGLTGGKAGNRIPQISSKKSPLE | ||||||
Region | 727-808 | Disordered | ||||
Sequence: EIHGSQAAMSMSESSRSLSPNSTEPDTPSPTGLTGGKAGNRIPQISSKKSPLEEDSGSTGEDTDSAASRKKHTFKIFKKQKK |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length808
- Mass (Da)90,503
- Last updated2022-08-03 v1
- ChecksumECC69D137D36276E
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M2BKR0 | A0A8M2BKR0_DANRE | stim1a | 781 | ||
Q1LY88 | Q1LY88_DANRE | stim1a | 676 | ||
A0A2R8RIM0 | A0A2R8RIM0_DANRE | stim1a | 703 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 589-612 | Polar residues | ||||
Sequence: ASSSHIPHSSSVAPHASHYHSSHF | ||||||
Compositional bias | 625-639 | Basic and acidic residues | ||||
Sequence: ASPERPRHCGSHGDL | ||||||
Compositional bias | 727-779 | Polar residues | ||||
Sequence: EIHGSQAAMSMSESSRSLSPNSTEPDTPSPTGLTGGKAGNRIPQISSKKSPLE |
Keywords
- Technical term