A0A8M2BJY4 · A0A8M2BJY4_DANRE

Function

function

Catalyzes the deimination of arginine residues of proteins.

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Features

Showing features for active site.

167550100150200250300350400450500550600650
TypeIDPosition(s)Description
Active site358
Active site479
Active site481
Active site657

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functioncalcium ion binding
Molecular Functionhistone arginine deiminase activity
Molecular Functionprotein-arginine deiminase activity
Biological Processvasculature development

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-arginine deiminase
  • EC number

Gene names

    • Name
      padi2
    • Synonyms
      sb:cb968
      , zgc:66317

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M2BJY4

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-108Protein-arginine deiminase (PAD) N-terminal
Domain110-281Protein-arginine deiminase (PAD) central
Domain292-672Protein-arginine deiminase C-terminal

Sequence similarities

Belongs to the protein arginine deiminase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    675
  • Mass (Da)
    76,190
  • Last updated
    2022-08-03 v1
  • Checksum
    D07FCE662105048A
MVSRRSLTIDTEKATKTTYVLGTTLTVNLIRCAPPQSKSFSIRCTPNVHYKITPPITDKNALPYPLGPNTILLITMDTVSETAFDSKLSVRYYGEKTETLGDAILHLTAVEISLDVDADRDGVVEKNNPNKASWKWGPNGHGAILLVNCDSESIYDKKPDNENSDIGKVSDLKDMSKMVLRTNGPSQLPEGYKLSMHISQSTSESVRVFRPRTNTKTENLWKYQLLKLFLKDFLMVVGTDTLTQEVPYLGGSSELEFHVEGLRFPDKDFDGLVTINLSLLEPCGKGFPETPIFTDKVVFRVSPWIMTPNTLKPVEVYVCSTEDNYSFLKSIRNLVEKSGYKLKICHEYMNRGDRWMQDELEFGYIDSPHHRFPVVLDSPRDGDLQDFPYDALLGPDFGYVTRNALNEEVSSLDSFGNLEVSPPVTVNGKNYPLGRIIIGVAFPTARKGRNMTKVVQDFLWAQKVQEPIALYSDWLFVGHVDEFMSFVPAPDRKKFRLLLASPDAGYKVFKSLQNSGLGKAEMFPGKEEAISVNDLLSDKKLQAENRYVQNCIDWNRDVLKKELGLDDEDIIDLPILFKVMEEKNEDSVPRAVAYYPDMVNMIVLGDQLGIPKPFGPQVKGVCALEKEMCSLLEPLGLKCTFIDDFAPYHKLLGEVHCGSNVLREPFTVRWWNLEL

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M2BJD0A0A8M2BJD0_DANREpadi2701
Q6PFK7Q6PFK7_DANREpadi2647

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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