A0A8M2BD93 · A0A8M2BD93_DANRE
- ProteinCholine transporter-like protein 2
- Geneslc44a2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids847 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- choline(out) + n H+(in) = choline(in) + n H+(out)
- ethanolamine(out) + n H+(in) = ethanolamine(in) + n H+(out)
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | mitochondrial outer membrane | |
Cellular Component | plasma membrane | |
Molecular Function | antiporter activity | |
Molecular Function | transmembrane transporter activity | |
Biological Process | transmembrane transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCholine transporter-like protein 2
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M2BD93
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Mitochondrion outer membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 34-55 | Helical | ||||
Sequence: ILCCILFILALLGYFAVGILAW | ||||||
Transmembrane | 234-254 | Helical | ||||
Sequence: WHWILLGLVIAMLISLIFILL | ||||||
Transmembrane | 261-279 | Helical | ||||
Sequence: VMVWVMIIMVIIVIGYGIF | ||||||
Transmembrane | 317-338 | Helical | ||||
Sequence: WLAFMIILCIVEAVILLLLIFL | ||||||
Transmembrane | 359-382 | Helical | ||||
Sequence: VMSSLFYPLLTYALMSLVIAYWAI | ||||||
Transmembrane | 454-481 | Helical | ||||
Sequence: LFFWCVNFVIALGQVTLAGAFASYYWAF | ||||||
Transmembrane | 502-524 | Helical | ||||
Sequence: YHTGTLAFGSLILAIVQVIRVVL | ||||||
Transmembrane | 602-625 | Helical | ||||
Sequence: FLLFLGKLLIVGIVGICSFFFFTG | ||||||
Transmembrane | 637-664 | Helical | ||||
Sequence: LNYYWVPILTVVFGAYLIAHGFFSVYAM |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 742-847 | Disordered | ||||
Sequence: DQEEETPLNQETHIEEAPQETQTQAPEASAVAEEKPEEQVTAQEHEPTQATPQQNGPQEVDAEDKEEPGAQAEPPQAENLQAPEPEEPKPQENGPQESDTLLTPQE | ||||||
Compositional bias | 753-769 | Polar residues | ||||
Sequence: THIEEAPQETQTQAPEA | ||||||
Compositional bias | 784-799 | Polar residues | ||||
Sequence: QEHEPTQATPQQNGPQ |
Sequence similarities
Belongs to the CTL (choline transporter-like) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length847
- Mass (Da)95,339
- Last updated2022-08-03 v1
- ChecksumE77F104FA84FC5BC
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8M9PMF6 | A0A8M9PMF6_DANRE | slc44a2 | 847 | ||
A0A8M9Q038 | A0A8M9Q038_DANRE | slc44a2 | 845 | ||
A0A8N7T6P0 | A0A8N7T6P0_DANRE | slc44a2 | 845 | ||
A0A8M2BD10 | A0A8M2BD10_DANRE | slc44a2 | 717 | ||
E7F1Z8 | E7F1Z8_DANRE | slc44a2 | 717 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 753-769 | Polar residues | ||||
Sequence: THIEEAPQETQTQAPEA | ||||||
Compositional bias | 784-799 | Polar residues | ||||
Sequence: QEHEPTQATPQQNGPQ |
Keywords
- Technical term