A0A8M2BBD6 · A0A8M2BBD6_DANRE

Function

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentmonoatomic ion channel complex
Cellular Componentplasma membrane
Molecular Functioninward rectifier potassium channel activity
Molecular Functionmonoatomic ion channel activity
Molecular Functionpotassium channel activity
Molecular Functionvoltage-gated potassium channel activity
Biological Processheart contraction
Biological Processmembrane repolarization during cardiac muscle cell action potential
Biological Processpotassium ion transmembrane transport
Biological Processregulation of heart contraction
Biological Processregulation of heart rate by cardiac conduction
Biological Processregulation of ventricular cardiac muscle cell membrane repolarization

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Potassium voltage-gated channel subfamily H member 6 isoform X1

Gene names

    • Name
      kcnh6a
    • Synonyms
      erg
      , kcnh2
      , kcnh6

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M2BBD6

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane372-396Helical
Transmembrane512-538Helical
Transmembrane583-599Helical
Transmembrane611-635Helical

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region213-256Disordered
Compositional bias237-256Basic and acidic residues
Domain714-814Cyclic nucleotide-binding
Region845-875Disordered
Region1052-1185Disordered
Compositional bias1054-1068Pro residues
Compositional bias1074-1096Polar residues
Compositional bias1107-1133Polar residues

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,185
  • Mass (Da)
    132,198
  • Last updated
    2022-08-03 v1
  • Checksum
    35425945AAF00F70
MPVRRGHVALQNTYLDTIIRKFDGQNRKFLIANAQMKNCGIIYCNEGFCQMFGFSRAEIMQQSCTCQFLVGPGTMKSALGQLAQALLGSEERKVEILYYSKEGTCRPCLIDVIPVKNEEGVVIMFILNFQELLDPSMKKGGLKQRMANSWLRAGQRRRMHLRMPSLRVKRQPSLPKDHFEGVVVDYLQPSHEEVALKDLQMSPDSCLKSETQALIQQTPSSCELSPPPSRPSDRLEPSGPLLKHSHSRESMHSLRRASSLHDIDGMRDQWSDLKPSNLNSTSDSDLMRHRTIGRIPQVTISFGSDRLRPPSPTEIEIIAPSKIKDRSQNVSEKVTQVTQVLSLGADVLPEYKLQAPRIHKWTILHYSPFKAVWDWIILLLVLYTAVFTPYSAAFLLNEQEDERRRTCGYTCNPLNVVDLVVDVMFIIDILINFRTTYVNHNDEVVSNPARIAQHYFKGWFLIDIVAAIPFDLLIFRSGSDEPQTTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMERTSSARIGGMKIGWLDNLADQIGKQYNDSNSFSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNPEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPGGLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQNCKAFRGASKGCLRALAMRFRTTHAPPGDTLVHSGDVLTALYFISRGSIEILRDDVVVAILGKNDIFGEPISLYARPGKSSADVRALTYCDLHKILRDDLLEVLDMYPDFSDNFWSNLEITFNLRDVDRIMHPTPSEDSDCGYRRPRHRRNPLRRNRPDGMDRDGMDTYPVQPCSPVGNHRGAIPLSQWDELCSDGSPASLSSEEDMKPLVSGQGDMYSLGTEMQEFSPSAVSLMPSAHSTASAMAGPLTGAHQYTAPLNISGVYSYLSDRRASEYSESQRRSSAVQACYHHHSPCVGDRPNQLQARLELLQSQLNRLETRMTADINVILQLLQRQMAPVPPAYSAVSPDPLAHPAPPAHPTSLYTTAAHNTTPSLQITDASSPGKSPDVDSLKEKSPDSLSSGIHLTVASTDTMSMSPETELSVPSAGPLLQPPGLLCSSLRFPSLPDSLEGPGTLEGSPEIQRHVSDPVLPGS

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q8JH78Q8JH78_DANREkcnh6a1186
A0A8M3AQY1A0A8M3AQY1_DANREkcnh6a856
A0A8M2BBB6A0A8M2BBB6_DANREkcnh6a915

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias237-256Basic and acidic residues
Compositional bias1054-1068Pro residues
Compositional bias1074-1096Polar residues
Compositional bias1107-1133Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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