A0A8M2B598 · A0A8M2B598_DANRE

Function

Features

Showing features for active site.

128222004006008001,0001,2001,4001,6001,8002,0002,2002,4002,6002,800
TypeIDPosition(s)Description
Active site2791Glycyl thioester intermediate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionRNA binding
Molecular Functionubiquitin binding
Molecular Functionubiquitin-ubiquitin ligase activity
Molecular Functionzinc ion binding
Biological Processpositive regulation of canonical Wnt signaling pathway
Biological Processprotein polyubiquitination

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • E3 ubiquitin-protein ligase UBR5 isoform X5

Gene names

    • Name
      ubr5
    • Synonyms
      edd1
      , wu:fa16c12

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M2B598

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain, zinc finger.

Type
IDPosition(s)Description
Region79-202Disordered
Compositional bias89-103Polar residues
Compositional bias120-141Polar residues
Compositional bias356-371Basic and acidic residues
Region356-376Disordered
Region607-676Disordered
Compositional bias611-630Basic and acidic residues
Compositional bias639-660Polar residues
Region1027-1107Disordered
Compositional bias1045-1063Pro residues
Compositional bias1076-1100Polar residues
Domain1207-1275UBR-type
Zinc finger1207-1275UBR-type
Region1545-1770Disordered
Compositional bias1556-1581Polar residues
Compositional bias1593-1607Acidic residues
Compositional bias1652-1681Polar residues
Compositional bias1690-1715Polar residues
Compositional bias1729-1770Polar residues
Region1887-1916Disordered
Region2015-2052Disordered
Compositional bias2027-2046Basic and acidic residues
Region2146-2170Disordered
Compositional bias2360-2393Basic and acidic residues
Region2360-2414Disordered
Domain2400-2477PABC
Region2493-2523Disordered
Compositional bias2495-2514Basic and acidic residues
Domain2538-2822HECT

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,822
  • Mass (Da)
    310,224
  • Last updated
    2022-08-03 v1
  • Checksum
    4E6E1B08ABE7FB21
MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNCNSHPHLIPLEQAKLKQCVVGPNHAGFLLEDGRICRISFAVQPDRLELGKPDGNDGSKLSSVSGAGRSSRPGRTSDPPWFLSGSDTLGRLAGNTLGTRWSSGVNGGGSGGGGSSGGGAGGGSGSGGGAGGGTGGGGSSGRSSTAARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSELLRERESVLRLRERRWLDGASFDAERGSTSREGEPSLDKKSVPLQSPVTLGEELQWWPDKDYVTKFVSIGALYSELVAVSTKGELYQWKWNEPEPYRNAQNPSIHHPRVPFLGLTNEKITHLSANSIRATVATENNKVATWVDETLSTVAAKLEHGAQTFPELQGERIVSLHCCALYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSIPNITVGTQVCLRNNPLYHAGAVAFSVNAGIPKVGVLLESVWNMNDSCRFQLRSPESLKNMEKNTKTQETKTESKPELVKTEMGPPPSPASTCSDTSSIASSASLPYKRRRSTPAPKEEEKVNEEQWPLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGTSSSVSSQSAAPTDSDPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIPEKAEILAVNVDSKGVHAVLKTGSWVRYCVFDLATGKAEQENHFPTSNLAFLGQSERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPIASLGMGVHSLANLPSNSTIKKKAAIIIMAVEKQTLMQHVLRCDYEACRQYLISLEQAMLLEQNPHALDTLLGHRCDGNRNVLHACVSVCFPVSNKETKEEEEAERSERNTFAERLSAVEAIANAISVVSSNSSGNRTGSSSSRGLRLREMMRRSLRAAGLGRHESGPSSSDHQDPVSPPIAPPSWVPDPPPMDPDGDIDFILAPAVGSLTTASTGTSQGPSTSTIPGPSSEPSVVESKDRKANAHLILKLMCDSIVLRPHLRELLSAKDARGMTPFMLAVSGRAYPAAITVLEAAQKIAKGEPGLGEKEDTASVFMEMICPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKAARLDLLYRLLTTTNLVTTPNSRGEHILLFLVQTVARQSVEHCQYRPPRIREDRNRKAASAEDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIAHLLPEEQMYLNQQSGTIRLDCFTHCLIVKCAPDITFIDTLLGTLVKELQNKYTPGRREEAINVTRRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCRRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAVQGSEELFSVEPLPPRPSPDQSSSSSQSASSYIIRNPQPRRSSQSQTARGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDDQEEQGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQSDDVDQETFLLDEPLERTTGSAHANSAAQAPRSMQWAVRTTPSQRSGGGAPSSSSAPAASSTGLIYIDPSNLRRSSAISTSAAAAAAALEASNSSSYLTSASSLARAYSIVIRQISDLMSLIPKYNHLVYSQYPAAVKLTYQDAVNLQNFVEDKLIPTWNWMVSIMDSTEAQLRYGSALSSAGDPGHPSHPLHASQHAGRRERMTAREEASLRTLEGRRRAATLLTARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNLQTTLDTTQIDRKRNRELLELGLDNEDSEHENDEDTNQSSTLQDKDEEPVPAETGQHHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSYMASKGLTDLTVDMNCLQILPTKMSYSANMKNVMSMESRQRGGEEQPVAEQEMDVSKPGPSPHDLAAQLKSSLLAEIGLTESDGPPLPTFIPHCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNLQSRDLALEVDRDREQLIQQTMRQLNAHFGRRCTTTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNDKLPNLDCVQSVSKGMQASNLMQRLRNRDRERERRSGGLRAASRRDRDRDSRRQLSIDTRPFRPASEGNPSDEPEPLPAHRQALGERLYPRVHAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVEEAMELLITHGRENGADSILDLGLLDTPEKAQQENRKRHGSTRSVVDMELDDPDDGDDNAPLFYQPGKRGFYSPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLIRHSQTEEAEAVFAAMDLAFAIDLCKEEGAGQVELLSGGVNMPVTPLNVYEYVRRYAEHRMLVVAEQPLHAMRKGLLDVLPKNALEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9PJ96A0A8M9PJ96_DANREubr52833
A0A8M9PM86A0A8M9PM86_DANREubr52822
A0A8M1NV16A0A8M1NV16_DANREubr52794
A0A8M9PJA4A0A8M9PJA4_DANREubr52793
A0A8M9P7S4A0A8M9P7S4_DANREubr52828
A0A8M2B4T2A0A8M2B4T2_DANREubr52816
A0A8M9NZ45A0A8M9NZ45_DANREubr52832
A0A8M9PCY7A0A8M9PCY7_DANREubr52827

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias89-103Polar residues
Compositional bias120-141Polar residues
Compositional bias356-371Basic and acidic residues
Compositional bias611-630Basic and acidic residues
Compositional bias639-660Polar residues
Compositional bias1045-1063Pro residues
Compositional bias1076-1100Polar residues
Compositional bias1556-1581Polar residues
Compositional bias1593-1607Acidic residues
Compositional bias1652-1681Polar residues
Compositional bias1690-1715Polar residues
Compositional bias1729-1770Polar residues
Compositional bias2027-2046Basic and acidic residues
Compositional bias2360-2393Basic and acidic residues
Compositional bias2495-2514Basic and acidic residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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