Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A8M2B4J8 · A0A8M2B4J8_DANRE

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Functionsequence-specific DNA binding
Biological Processangiogenesis
Biological Processblood vessel morphogenesis
Biological Processregulation of DNA-templated transcription
Biological Processregulation of transcription by RNA polymerase II
Biological Processvasculogenesis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Fli-1 proto-oncogene, ETS transcription factor b isoform X7

Gene names

    • Name
      fli1rs
    • Synonyms
      fli1b
      , zgc:5777174

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M2B4J8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-97Disordered
Compositional bias22-41Polar residues
Compositional bias48-95Polar residues
Domain87-173PNT
Region204-238Disordered
Region251-281Disordered
Compositional bias264-281Polar residues
Domain288-368ETS

Sequence similarities

Belongs to the ETS family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    457
  • Mass (Da)
    51,681
  • Last updated
    2022-08-03 v1
  • MD5 Checksum
    9F8DBDAF9F8D472541A5453EA6045CC8
MHMKAEIGSPAVFRQASEESIEPTEPDWSGSAAQNSAKRAEHINGTSHESPVDCSVTKRTRHMSNSDGGQLSYQASYPEPRSSPQTATPPSSTTEEKRVIVPADPEVWTQDHVRQWVDWAIKEYALSDVDVSLFQTLDGKALCKLSKEDMMRITSAYNTDILLSHLNYLRESSPTFSYPTNPTNTQPQPRVQVKAENSFEEIGRRNSWSSSGLPAVPKGSPIEHQHNTRITEPPPRLPQDPYQALGSISSRLANPEAKPIHTKNRTTKQNSSHLPVSSTDRTVGSGQIQLWQFLLELLSDSNNSTIITWEGTNGEFKMTDPDEVAKRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFQGISQSHQNHSTEGSVYKFQTEGSYMQSYHSHQPKMNFISPHSTPMSVTTSNFFTPQSTYWNSATSVVYPSSPMPRHPSTHTHLNTYY

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M3ATP1A0A8M3ATP1_DANREfli1rs496
A0A8M2B4J0A0A8M2B4J0_DANREfli1rs429
A0A8M2B4K4A0A8M2B4K4_DANREfli1rs458
A0A8M3AID3A0A8M3AID3_DANREfli1rs468
A0A8M3B1W4A0A8M3B1W4_DANREfli1rs467
A0A8M2B528A0A8M2B528_DANREfli1rs486
A0A8M3AQV9A0A8M3AQV9_DANREfli1rs495
Q5MBG6Q5MBG6_DANREfli1rs458

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias22-41Polar residues
Compositional bias48-95Polar residues
Compositional bias264-281Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help