A0A8M2B421 · A0A8M2B421_DANRE

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin (UniProtKB | Rhea| CHEBI:59560 )

FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

heme b (UniProtKB | Rhea| CHEBI:60344 )

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentnucleus
Cellular Componentplasma membrane
Molecular Functioncalmodulin binding
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionFMN binding
Molecular Functionmetal ion binding
Molecular Functionnitric-oxide synthase activity
Biological Processarginine catabolic process
Biological Processdefense response to bacterium
Biological Processinflammatory response
Biological Processinflammatory response to wounding
Biological Processnegative regulation of blood pressure
Biological Processnitric oxide biosynthetic process
Biological Processnitric oxide mediated signal transduction
Biological Processresponse to hormone
Biological Processresponse to lipopolysaccharide
Biological Processresponse to wounding
Biological Processswimming behavior

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    nitric-oxide synthase (NADPH)
  • EC number

Gene names

    • Name
      nos2b
    • Synonyms
      inosb

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M2B421

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain96-234Flavodoxin-like
Domain283-527FAD-binding FR-type

Sequence similarities

Belongs to the NOS family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    687
  • Mass (Da)
    77,231
  • Last updated
    2022-08-03 v1
  • Checksum
    5FAA4513F9C95F22
MQHMEMEVRLRGGCPADWVWLVPPMSGSLTPVFHQEMLNYILSPFFYYQPEAWLTHKWKDMKRKARRCTISFKGLIRVVLFSQALIKLAMAKRVCCTVLYATETGKSQTFAKKLNGIMNCCFSSRVVCMEDYNVSELEKESLLIVVTSTFGNGDCPGNGESFKKQLLSLKTLRTKVRYCVFGLGSRMYPHFCAFAHALDAMFASLGAIRVSSTGEGDELKGQEESFSSWACTAFKDACKEFNVQGQLPGTDCLVDSWDSQRYRVQNDSCTVDRITALSTLHSKAVVPMKLKRRQNLQSAKSSCATILVELEMEGNTEPLNFTPGDHVGIFAGNSPGLVAGILKHLSNANPINQSLQLEFLSAHADGERWQRDERIPPCSLAQALTYYLDVTSPPSQSLLRKLSKIARQEDHRQHLLALASDFQVYTTWKDFFKPTFLEVLEEFPSLELSAAFLLSQLPLLKPRLYSISSSPDLHPQELHLTVAVISYYTQEGKGPLHFGLCSNWLNTIKEGDTVPCFLHSSDWFHLPSDPNAPCILVGVGSGIAPFRSFWQQQFHDMNKTGLKGNPMTLVFGCRSSDTDHLYKEEILDMRDNGTLSSITTAYSRQTGQAKVYVQDILREQLNDKIFEVLHHNSGHVYVCGGVNMACDVAATVKEILVNQMGITVAQAEEYLSRLKNEKRYHEDIFGY

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A9JNR5A9JNR5_DANREnos2b1077
A0A8M3AHD3A0A8M3AHD3_DANREnos2b939
F1QML0F1QML0_DANREnos2b1077

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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