A0A8M2B3I7 · A0A8M2B3I7_DANRE
- ProteinCytosolic purine 5'-nucleotidase
- Genent5c2a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids574 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Catalytic activity
- AMP + inosine = adenosine + IMP
- CMP + inosine = cytidine + IMP
- GMP + H2O = guanosine + phosphateThis reaction proceeds in the forward direction.
- GMP + inosine = guanosine + IMP
- H2O + XMP = phosphate + xanthosineThis reaction proceeds in the forward direction.
- dGMP + H2O = 2'-deoxyguanosine + phosphateThis reaction proceeds in the forward direction.
- dGMP + inosine = 2'-deoxyguanosine + IMP
- dIMP + H2O = 2'-deoxyinosine + phosphateThis reaction proceeds in the forward direction.
- dIMP + inosine = 2'-deoxyinosine + IMP
- inosine + UMP = IMP + uridine
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 5'-nucleotidase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | transferase activity | |
Biological Process | GMP metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytosolic purine 5'-nucleotidase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA0A8M2B3I7
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length574
- Mass (Da)66,525
- Last updated2022-08-03 v1
- Checksum197CA483ECC46C0D
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
E7FC21 | E7FC21_DANRE | nt5c2a | 561 | ||
A0A8M9QJJ3 | A0A8M9QJJ3_DANRE | nt5c2a | 530 |
Keywords
- Technical term