A0A8L7TH03 · A0A8L7TH03_BRUMA

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site, active site.

1734100200300400500600700
Type
IDPosition(s)Description
Binding site397Zn2+ (UniProtKB | ChEBI); catalytic
Active site398
Binding site401Zn2+ (UniProtKB | ChEBI); catalytic
Binding site407Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processmembrane protein ectodomain proteolysis
Biological ProcessNotch signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    ADAM 17-like protease

Organism names

  • Taxonomic identifier
  • Strain
    • FR3
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Brugia

Accessions

  • Primary accession
    A0A8L7TH03

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane668-687Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain222-465Peptidase M12B
Domain466-561Disintegrin

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    734
  • Mass (Da)
    83,002
  • Last updated
    2022-08-03 v1
  • MD5 Checksum
    227B1348BBD4C8AAFC3C83BC62FC403C
MLLLLLFFWRQIIIIVSFHFQFYTCLLINDAFTINGDKKINLNERLKYYEIIEINRRIEKRGIVDNNISYNKQQRLTFRAFNRFFDIYLTPKKGILHANFKCREIDGYGYEKLCTVNPDEYFGGHLHGVANSIVAISYSDEGSLLGTVQSDGEIYIFEPAKIHFETAHPWQILAYRNSDLKFNFELNNRSFCSSILIGNSNNITFSQSMRFKRLSALPTTKNRCSLRVVADYRFFRTIGNGSQAFSARYLINVIDRINTLYTVTDWGIDEDGRRLINMGFMIKEMIIHTSPTVNQPNHYNSNINTKRNVKAILDNFSRNQGSDKYCLVHLFTAQSFENGVLGLAYISSPELDAAGGICSIQNRDRLGVVYYNTALSSTKATHGVTVVSREADIVTAHELGHNWGATHDDLSVECSPPYSLGGSYIMNTFSVSGYDENNNRFSPCSRRLIGKVLSRKANICFEPEMNAFCGNGKVENDTNGFAEECDVGSLLSGITDQCCTSDCRFKPNAICSPKNSPCCSSNCQFLPSTHLCLHENRFQCKLSSYCTGNSGECPEPGFVQDGTPCIEDGECLNGHCLTFCEKPSVNKKPCMCSREAVACLRCCRSENGTCEPYSYDPKYILKDGTRCIHGTCLRAICIKEVADVISHFWSIIENIDEKNFWKFVGDNLVGIIAAIVLIIWIPASIIIHKIDKAREIAAINESENRIEIVGEKSIYKYIINSYSEEDDIDRNSRY

Keywords

Genome annotation databases

Similar Proteins

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