A0A8L7TBK0 · A0A8L7TBK0_BRUMA

Function

Catalytic activity

  • 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O = 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • 1-O-alkyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O = 1-dodecanoyl-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O = 1-tetradecanoyl-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • H2O + sn-glycerol 3-phosphocholine = glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
    EC:3.1.4.38 (UniProtKB | ENZYME | Rhea)
  • H2O + sphing-4-enine-phosphocholine = H+ + phosphocholine + sphing-4-enine
    This reaction proceeds in the forward direction.
  • a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.
  • glycero-2-phosphocholine + H2O = glycerol + H+ + phosphocholine
    This reaction proceeds in the forward direction.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

GO annotations

AspectTerm
Cellular Componentmembrane
Biological Processlipid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glycerophosphocholine cholinephosphodiesterase
  • EC number
  • Alternative names
    • Choline-specific glycerophosphodiester phosphodiesterase
    • Ectonucleotide pyrophosphatase/phosphodiesterase family member 6

Gene names

    • Name
      Bm1_06255

Organism names

  • Taxonomic identifier
  • Strain
    • FR3
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Brugia

Accessions

  • Primary accession
    A0A8L7TBK0

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane445-468Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-17
ChainPRO_503547540618-472glycerophosphocholine cholinephosphodiesterase

Keywords

Family & Domains

Sequence similarities

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    472
  • Mass (Da)
    54,980
  • Last updated
    2022-08-03 v1
  • Checksum
    3A5957A4C8CA4680
MWYCQYIFCIIAHFVAATEKIPCGQNLIVFIIDGYGKALLNQSDIGFRLLTQNGVYSDFLKPVYPTHNYPNWMSLVTGLYAENHGFGANYMWDRVKNRRFWKGETNRVGDSWWPDGVVPAWYTTGKSNVDVHCYWMPGCDLPYQDIIVQVPQERKYNASLPEQTDALMSYFPEIIERITKYQPYRQQFFLIRYAGVQAALETFGLRSDELKQALINVDLSLLLLQQKLDAEKLFESTNLMVISTHGLYTVEQEEQFFIEECLTDYSKIQKVVNHHAMMMIFTNPDEANEVFFELKLCDQWAPMGDYDENEQPLVSVYQTTELPDRFHWKNFQYMPEIVLITRPGATVLTRELPSLPPHDEQERDILLTGGWDNENLNMHGIFFARGPAFKEDYEASDINVVDIYQVMMNIFGIEPPHRHNGTWSNVEDFLSSGWETRSVPENMRAFTVTSCQISLMCFTILISSFMIYDQFL

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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