A0A8L7SWF6 · A0A8L7SWF6_BRUMA

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site, active site.

111051002003004005006007008009001,0001,100
Type
IDPosition(s)Description
Binding site719ATP (UniProtKB | ChEBI)
Active site827Proton acceptor
Binding site831ATP (UniProtKB | ChEBI)
Binding site832Mg2+ (UniProtKB | ChEBI)
Binding site845Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentreceptor complex
Cellular Componentsynapse
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functiontransmembrane receptor protein tyrosine kinase activity
Molecular FunctionWnt-protein binding
Biological Processanatomical structure morphogenesis
Biological Processcell surface receptor protein tyrosine kinase signaling pathway
Biological Processpositive regulation of kinase activity
Biological Processpositive regulation of neuron projection development
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • Name
      Bm1_42855

Organism names

  • Taxonomic identifier
  • Strain
    • FR3
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Brugia

Accessions

  • Primary accession
    A0A8L7SWF6

Proteomes

Subcellular Location

Membrane
; Single-pass type I membrane protein
Synapse

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond493↔516

Keywords

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region34-67Disordered
Domain101-194Ig-like
Domain279-421FZ
Domain445-521Kringle
Region654-673Disordered
Domain685-962Protein kinase
Region967-1025Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,105
  • Mass (Da)
    123,427
  • Last updated
    2022-08-03 v1
  • Checksum
    2588821782D8EB9F
MDDLSSIENVNHKKVLVKLDKMALKPITKKESVQKLNDLKSGRKPQQEDAGTKIAKQRKSESDMVPKPYDDLFIEPAGDYDIVYADYNMTMEDGSSPSKRPYIRLTSFLNNVTKNAGDEVRFKCEAAGSPLPLQFSWLKNHAPVEKNRKLKIKNREYWSRLVITDLEVLDSGYYQCVVSNSLASVNTTAVLRVSNVLDGKSSNINKLKGKSTSRISNFQNEEYFEEDFEGPGSSMSGGLGRLQSEEESEDSLWNVPNNAAGPGYAPIAPSDRWLDGLNANVGDCIVYRGEACREYLTGRHVMIVSDNREDMYDVDRNLRAAMMFINSSPVISAQCKHYSHAVACYHMYKICDRGPGTDYRATSGMPNILTICRKDCDALQADLCPKELALAAEHDLVGDDPKALLPKCQSLNPKAEYCIPIISVADQSEGNTDLSPDFPKELPHWCYMDSGKTYEGNASLTKSGKRCMNWTQSSSREFNIDRYPSLRTSRNHCRNPGGKKSSPWCFTHPNGQEEYCDISQCPPSMYPYLRDREVMGTIDDDGSIIGDISDIWSNLSSPWQLAILGGFGFFIFSLILLCCYCCCRRRRSEAASSSAIKKNGLQNCNGCSIASSAVNSTYYRKLNGTANTDPNNAAFELSSLIQAPTNSTTFMQHHHSGSYAQYSPRPSTEPSVEPYQIPEIQSSQLQIGDLIGEGQFGMIHNGSWHGSLLNGEPIQVAVKSLKSGSSAVERQNFEEEIRTIAPFDHPNVVRLLGVCYFDTQQLSAVFEYMVHGDLHDFLLLRAPKTNGYEQVIDQERIIADNEDFLRIALQIAYGMKYLSSMNFVHRDLAARNCLVADQRVIKIADFGLVRNCYEKDYYKVMHRTWLPVRWMSQEAIQCGRFNEATDVWSFGVTLWEIYSYGRQPYESYSNQDVIELICVRSLLECPQNCPTNIYSLMVECWHEHPERRPTFSELYSRLQTWSLTSPSQSVLSHQQNHPGSSHSDSSAAANRGSRQSSSTPSLSLLRGTTGNTSLGTAPSMATTAFSVPSPAPMQTMMTLNGVHPYQVGSTHLVSGGNHNRSPKTRLQNTATRTSNNTMTTASLMRHQGTSHFNYSGDDAASEESD

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8L7SWH3A0A8L7SWH3_BRUMABm1_428551042
A0A8L7SWL6A0A8L7SWL6_BRUMABm1_428551050
A0A8L7SWE6A0A8L7SWE6_BRUMABm1_42855987

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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