A0A8L7SWF6 · A0A8L7SWF6_BRUMA
- Proteinreceptor protein-tyrosine kinase
- GeneBm1_42855
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1105 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 719 | ATP (UniProtKB | ChEBI) | |||
Active site | 827 | Proton acceptor | |||
Binding site | 831 | ATP (UniProtKB | ChEBI) | |||
Binding site | 832 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 845 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | receptor complex | |
Cellular Component | synapse | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | transmembrane receptor protein tyrosine kinase activity | |
Molecular Function | Wnt-protein binding | |
Biological Process | anatomical structure morphogenesis | |
Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | |
Biological Process | positive regulation of kinase activity | |
Biological Process | positive regulation of neuron projection development | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namereceptor protein-tyrosine kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Spiruromorpha > Filarioidea > Onchocercidae > Brugia
Accessions
- Primary accessionA0A8L7SWF6
Proteomes
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 493↔516 | ||||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 34-67 | Disordered | |||
Domain | 101-194 | Ig-like | |||
Domain | 279-421 | FZ | |||
Domain | 445-521 | Kringle | |||
Region | 654-673 | Disordered | |||
Domain | 685-962 | Protein kinase | |||
Region | 967-1025 | Disordered | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,105
- Mass (Da)123,427
- Last updated2022-08-03 v1
- Checksum2588821782D8EB9F
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8L7SWH3 | A0A8L7SWH3_BRUMA | Bm1_42855 | 1042 | ||
A0A8L7SWL6 | A0A8L7SWL6_BRUMA | Bm1_42855 | 1050 | ||
A0A8L7SWE6 | A0A8L7SWE6_BRUMA | Bm1_42855 | 987 |
Keywords
- Technical term