A0A8L2UMW0 · A0A8L2UMW0_RAT

  • Protein
    mitogen-activated protein kinase kinase
  • Gene
    Map2k7
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionJUN kinase kinase activity
Molecular Functionmagnesium ion binding
Molecular FunctionMAP kinase activity
Molecular Functionprotein kinase binding
Molecular Functionprotein phosphatase binding
Biological Processcellular response to interleukin-1
Biological Processcellular response to lipopolysaccharide
Biological Processpositive regulation of DNA-templated transcription
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of JNK cascade
Biological Processpositive regulation of JUN kinase activity
Biological Processpositive regulation of telomere maintenance
Biological Processprotein phosphorylation
Biological Processregulation of motor neuron apoptotic process
Biological Processresponse to heat
Biological Processresponse to osmotic stress
Biological Processresponse to tumor necrosis factor
Biological Processresponse to UV
Biological Processresponse to wounding
Biological Processstress-activated MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    mitogen-activated protein kinase kinase
  • EC number

Gene names

    • Name
      Map2k7

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8L2UMW0

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain120-380Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    452
  • Mass (Da)
    50,972
  • Last updated
    2022-08-03 v1
  • Checksum
    51A0E503A6C0A73F
MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPTLQLPLANDGGSRSPSSESSPQHPTPPSRPRHMLGLPSTLFTPRSMESIEIDQKLQEIMKQTGYLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKHYETLEVDVASWFKDVMAKTESPRTSGVLSQHHLPFFSGSLEESPTSLPFPKSFPLSPAIPLAQAEWVLGR

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q4KSH7MP2K7_RATMap2k7419
A6KQ64A6KQ64_RATMap2k7435

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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