A0A8L2RC24 · A0A8L2RC24_RAT
- ProteinKinesin light chain
- GeneKlc1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids565 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | kinesin complex | |
Cellular Component | microtubule |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameKinesin light chain
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8L2RC24
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Oligomeric complex composed of two heavy chains and two light chains.
Structure
Family & Domains
Features
Showing features for coiled coil, compositional bias, region, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 89-151 | |||||
Sequence: MMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLEFM | ||||||
Compositional bias | 156-178 | Basic and acidic residues | ||||
Sequence: KYDDDISPSEDKDSDSSKEPLDD | ||||||
Region | 156-203 | Disordered | ||||
Sequence: KYDDDISPSEDKDSDSSKEPLDDLFPNDEDDPGQGIQQQHSSAAAAAQ | ||||||
Compositional bias | 187-201 | Polar residues | ||||
Sequence: PGQGIQQQHSSAAAA | ||||||
Repeat | 297-330 | TPR | ||||
Sequence: AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKV |
Sequence similarities
Belongs to the kinesin light chain family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length565
- Mass (Da)64,029
- Last updated2022-08-03 v1
- ChecksumC8FF08149EFEBD93
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P37285 | KLC1_RAT | Klc1 | 560 | ||
A0A140TAB3 | A0A140TAB3_RAT | Klc1 | 552 | ||
A0A8L2QTG3 | A0A8L2QTG3_RAT | Klc1 | 551 | ||
A0A8I5ZN87 | A0A8I5ZN87_RAT | Klc1 | 593 | ||
A0A8I5ZU72 | A0A8I5ZU72_RAT | Klc1 | 585 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 156-178 | Basic and acidic residues | ||||
Sequence: KYDDDISPSEDKDSDSSKEPLDD | ||||||
Compositional bias | 187-201 | Polar residues | ||||
Sequence: PGQGIQQQHSSAAAA |
Keywords
- Technical term