A0A8L2QEI7 · A0A8L2QEI7_RAT

  • Protein
    Dual specificity mitogen-activated protein kinase kinase 2
  • Gene
    Map2k2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site101ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentearly endosome
Cellular Componentfocal adhesion
Cellular Componentlate endosome
Cellular Componentmitochondrion
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processprotein phosphorylation
Biological Processregulation of early endosome to late endosome transport
Biological Processregulation of Golgi inheritance
Biological Processregulation of stress-activated MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity mitogen-activated protein kinase kinase 2
  • EC number
  • Alternative names
    • ERK activator kinase 2
    • MAPK/ERK kinase 2

Gene names

    • Name
      Map2k2

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8L2QEI7

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain72-370Protein kinase
Region282-310Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    401
  • Mass (Da)
    44,381
  • Last updated
    2022-08-03 v1
  • Checksum
    61B082B12472C349
MLARRKPVLPALTINPTIAEGPSPTSEGASEAHLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLTNHAFIKRSEGEDVDFAGWLCRTLRLKQPSTPTRTAV

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P36506MP2K2_RATMap2k2400
A0A8I6AIR2A0A8I6AIR2_RATMap2k2366
A0A8I6AW22A0A8I6AW22_RATMap2k2376
A0A8I6A1A4A0A8I6A1A4_RATMap2k2394
A0A8I5ZPN3A0A8I5ZPN3_RATMap2k2422

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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