A0A8L2QED5 · A0A8L2QED5_RAT

  • Protein
    Histone acetyltransferase
  • Gene
    Bckdk
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Catalytic activity

Features

Showing features for active site.

152350100150200250300350400450500
TypeIDPosition(s)Description
Active site415Proton donor/acceptor

GO annotations

AspectTerm
Cellular Componentkinetochore
Cellular Componentmitochondrion
Cellular ComponentMLL1 complex
Cellular ComponentMSL complex
Cellular ComponentNSL complex
Cellular Componentnuclear matrix
Molecular Functionenzyme binding
Molecular Functionhistone H4K16 acetyltransferase activity
Molecular Functionhistone H4K5 acetyltransferase activity
Molecular Functionhistone H4K8 acetyltransferase activity
Molecular Functionmetal ion binding
Molecular Functionpromoter-specific chromatin binding
Molecular Functionprotein propionyltransferase activity
Molecular FunctionRNA polymerase II-specific DNA-binding transcription factor binding
Molecular Functiontranscription coactivator activity
Biological Processdosage compensation by inactivation of X chromosome
Biological Processmyeloid cell differentiation
Biological Processnegative regulation of DNA-templated transcription
Biological Processnegative regulation of epithelial to mesenchymal transition
Biological Processnegative regulation of type I interferon production
Biological Processneurogenesis
Biological Processoogenesis
Biological Processpositive regulation of skeletal muscle satellite cell differentiation
Biological Processpositive regulation of transcription initiation by RNA polymerase II
Biological Processpost-embryonic hemopoiesis
Biological Processregulation of autophagy
Biological Processregulation of mitochondrial transcription
Biological Processregulation of mRNA processing
Biological Processtranscription initiation-coupled chromatin remodeling

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Histone acetyltransferase
  • EC number

Gene names

    • Name
      Bckdk
    • Synonyms
      Kat8

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8L2QED5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-47Polar residues
Region1-48Disordered
Region81-116Disordered
Domain239-512MYST-type HAT

Sequence similarities

Belongs to the MYST (SAS/MOZ) family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    523
  • Mass (Da)
    59,679
  • Last updated
    2022-08-03 v1
  • Checksum
    BA675E84F663A50F
MSSKRKRNQIGPISSNNSPTEYALLNKTLPRHNLPTSNTQTMPAPTDPELKTSLCLIARITSGTAMAAQGATAAVAATTSGIVGEGEPGPGENTSVEGPARSPGRVSPPTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKFEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q00972BCKD_RATBckdk412
A0A0H2UHR5A0A0H2UHR5_RATBckdk459

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-47Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help