A0A8L2QDI9 · A0A8L2QDI9_RAT
- ProteinColony stimulating factor 1
- GeneCsf1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids593 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Glires (Rodents and rabbits) > Rodentia (rodent) > Myomorpha (mice and others) > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8L2QDI9
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 536-558 | Helical | ||||
Sequence: FVFWVLGIILVLLAVGGLLFYSW |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-32 | |||||
Sequence: MTARGAAGRCPSSTWMGSRLLLVCLLVSRSVA | ||||||
Chain | PRO_5035431935 | 33-593 | ||||
Sequence: EVSEHCSHMIGNGHLQILQQLIDSQMETACLIEYKFVDQEQLDDPVCYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSCFIKDYKEQNEHSLDRRHSVDPEDILGTRNSPSHPYSEACVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNCNDSFAKCSSRDVVTKPDCNCLYPKATPSSDLASASPHQPPAPSMAPLADLAWDDSQRTEGSSLLPSDLPLRIEDPGSAKQRPPRSTCQTLESTEQPNHEDPQPHPSAGAPIPGVEDIIESSMGTNWVLEEASGEASEGFLTQERKFSPSNPVGGSIQAETDRPWARSASSPFPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTDGSSTLREDQQEPRSPHFATLNPQRVGNSATPYAKLLPPKSHSWGIVLPLGELEGKKSTRDRRSPAELKGGPASEGAARPVAQSTRDRRSPAELKGGPASEGAARPVARFNSIPLTDTGSSIQDPQTSAFVFWVLGIILVLLAVGGLLFYSWKRRSHRDPRTLDSSVGRPEGSSLAQDEDRQVELPV | ||||||
Disulfide bond | 38↔121 | |||||
Sequence: CSHMIGNGHLQILQQLIDSQMETACLIEYKFVDQEQLDDPVCYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSC | ||||||
Disulfide bond | 62 | Interchain | ||||
Sequence: C | ||||||
Disulfide bond | 79↔197 | |||||
Sequence: CYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSCFIKDYKEQNEHSLDRRHSVDPEDILGTRNSPSHPYSEACVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNC | ||||||
Disulfide bond | 160↔204 | |||||
Sequence: CVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNCNDSFAKC | ||||||
Disulfide bond | 215 | Interchain | ||||
Sequence: C | ||||||
Disulfide bond | 217 | Interchain | ||||
Sequence: C |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 224-444 | Disordered | ||||
Sequence: PSSDLASASPHQPPAPSMAPLADLAWDDSQRTEGSSLLPSDLPLRIEDPGSAKQRPPRSTCQTLESTEQPNHEDPQPHPSAGAPIPGVEDIIESSMGTNWVLEEASGEASEGFLTQERKFSPSNPVGGSIQAETDRPWARSASSPFPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTDGSSTLREDQQEPRSPHFATLNPQRVGNSATPYAKLLP | ||||||
Compositional bias | 278-297 | Polar residues | ||||
Sequence: RPPRSTCQTLESTEQPNHED | ||||||
Compositional bias | 339-353 | Polar residues | ||||
Sequence: QERKFSPSNPVGGSI | ||||||
Compositional bias | 369-407 | Polar residues | ||||
Sequence: FPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTD | ||||||
Compositional bias | 421-435 | Polar residues | ||||
Sequence: SPHFATLNPQRVGNS | ||||||
Region | 461-511 | Disordered | ||||
Sequence: GKKSTRDRRSPAELKGGPASEGAARPVAQSTRDRRSPAELKGGPASEGAAR | ||||||
Region | 565-593 | Disordered | ||||
Sequence: DPRTLDSSVGRPEGSSLAQDEDRQVELPV |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length593
- Mass (Da)65,271
- Last updated2022-08-03 v1
- Checksum56F9DBEF828798D8
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q8JZQ0 | CSF1_RAT | Csf1 | 566 | ||
A0A0G2K4Q6 | A0A0G2K4Q6_RAT | Csf1 | 551 | ||
A0A8I6AN73 | A0A8I6AN73_RAT | Csf1 | 581 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 278-297 | Polar residues | ||||
Sequence: RPPRSTCQTLESTEQPNHED | ||||||
Compositional bias | 339-353 | Polar residues | ||||
Sequence: QERKFSPSNPVGGSI | ||||||
Compositional bias | 369-407 | Polar residues | ||||
Sequence: FPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTD | ||||||
Compositional bias | 421-435 | Polar residues | ||||
Sequence: SPHFATLNPQRVGNS |
Keywords
- Technical term