A0A8K1RCR8 · A0A8K1RCR8_LITCU
- ProteinNAD(P)H-quinone oxidoreductase subunit 3, chloroplastic
- GenendhC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids120 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Catalytic activity
- a plastoquinone + NADH + (n+1) H+(in) = a plastoquinol + NAD+ + n H+(out)
a plastoquinone RHEA-COMP:9562 + CHEBI:57945 + (n+1) H+ (in)CHEBI:15378= a plastoquinol RHEA-COMP:9561 + CHEBI:57540 + n H+ (out)CHEBI:15378 - a plastoquinone + NADPH + (n+1) H+(in) = a plastoquinol + NADP+ + n H+(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast thylakoid membrane | |
Cellular Component | mitochondrial membrane | |
Cellular Component | NADH dehydrogenase complex | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | quinone binding | |
Biological Process | photosynthesis, light reaction |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD(P)H-quinone oxidoreductase subunit 3, chloroplastic
- EC number
- Alternative names
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Magnoliidae > Laurales > Lauraceae > Litsea
Accessions
- Primary accessionA0A8K1RCR8
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion membrane ; Multi-pass membrane protein
Plastid, chloroplast thylakoid membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-34 | Helical | ||||
Sequence: AFLIISSVIPILAFLISGVLAPI | ||||||
Transmembrane | 62-83 | Helical | ||||
Sequence: YYMFALVFVVFDVETVFLYPWA | ||||||
Transmembrane | 89-112 | Helical | ||||
Sequence: LGVSVFIEALIFVLIPIVGSVYAW |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus.
Structure
Sequence
- Sequence statusComplete
- Length120
- Mass (Da)13,753
- Last updated2022-08-03 v1
- Checksum41A9EA5B647E0D4A