A0A8K1NCY4 · A0A8K1NCY4_HEMLE

  • Protein
    Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 1 [2Fe-2S] cluster.
[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Note: Binds 1 [3Fe-4S] cluster.
[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionelectron transfer activity
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity
Biological Processrespiratory electron transport chain
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • EC number

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Scorpiones > Iurida > Scorpionoidea > Hemiscorpiidae

Accessions

  • Primary accession
    A0A8K1NCY4

Subcellular Location

Mitochondrion inner membrane
; Peripheral membrane protein

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain67-1602Fe-2S ferredoxin-type
Domain203-2334Fe-4S ferredoxin-type

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    289
  • Mass (Da)
    33,175
  • Last updated
    2022-08-03 v1
  • Checksum
    28C750FE820B35A1
LAEREEFRKIYLSIFRCCEFGQCWKMSLTSLNKTLTFASLFKVAKRTSIRTAQTAAAVSPDTHSRIKKFSIYRYDPDKADEKPRMQTYEVDLNACGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCAMNIAGINTLACICKIDSDTSKATKIYPLPHMYVIKDLVPDMNNFYEQYRSIQPWLQKKDEGTVGQKQNLQSIDDRKKLDGLYECILCACCSTSCPSYWWNGDRYLGPAALMQAYRWVIDSRDQSTAERLDRLKDPFSVYRCHTIMNCTRTCPKGLNPGKY

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue289

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MZ151894
EMBL· GenBank· DDBJ
UDB72871.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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